國家衛生研究院 NHRI:作者相关文件

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"Chao, YS"的相关文件

类别	日期	题名	關聯
[黃嘯谷] 期刊論文	2013-06	A common environmental pollutant, 4-nonylphenol, promotes allergic lung inflammation in a murine model of asthma	-
[謝興邦] 期刊論文	2013-01	3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor	-
[謝興邦] 期刊論文	2012-12	An efficient, mild and scalable synthesis of bioactive compounds containing the angelicin scaffold	-
[李靜琪] 期刊論文	2016-05	N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors	-
[翁紹華] 期刊論文	2014-09	Discovery, structure-activity relationship studies, and anti-nociceptive effects of 1-phenyl-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one as novel opioid receptor agonists	-
[蔣維棠] 期刊論文	2013-06	Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	-
[李靜琪] 期刊論文	2015-07	Development and application of a fluorescent glucose uptake assay for the high-throughput screening of non-glycoside SGLT2 inhibitors	-
[蔣維棠] 期刊論文	2015-07	Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations	-
[岳嶽] 期刊論文	2013-05	Characterization of an efficient dengue virus replicon for development of assays of discovery of small molecules against dengue virus	-
[陳炯東] 期刊論文	2021-08-01	DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity	-
[鄒倫] 期刊論文	2021-01	BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy	-
[翁紹華] 期刊論文	2019-04-01	The in vivo antinociceptive and mu-opioid receptor activating effects of the combination of N-phenyl-2′,4′-dimethyl-4,5′-bi-1,3-thiazol-2-amines and naloxone	-
[陳志豪] 期刊論文	2019-04-01	A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus	-
[翁紹華] 期刊論文	2018-04	4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy	-
[李靜琪] 期刊論文	2018-01-01	Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2	-
[翁紹華] 期刊論文	2014-08	Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors	-
[陳炯東] 期刊論文	2012-09	Putative tumor metastasis-associated genes in human gastric cancer	-
[洪明秀] 期刊論文	2012-07	Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors	-
[夏克山] 期刊論文	2011-06	Hot topic: Opportunities and potential challenges for the treatment of metabolic syndrome	-
[李秀珠] 期刊論文	2011-11	Isolation and biological activities of phenanthroindolizidine and septicine alkaloids from the formosan tylophora ovata	-
[趙宇生(2002-2013)] 期刊論文	2011-01-13	Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes	-
[陳炯東] 期刊論文	2011-01	BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities	-
[趙宇生(2002-2013)] 期刊論文	2010-09-01	Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors	-
[陳新(2002-2015)] 期刊論文	2010-06-15	(2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV	-
[陳炯東] 期刊論文	2010-03	Synthesis and biological activities of 2-Amino-1-arylidenamino imidazoles as orally active anticancer agents	-
[謝興邦] 期刊論文	2010-02-01	Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor	-
[陳炯東] 期刊論文	2010-02	Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91	-
[陳志豪] 期刊論文	2009-11-01	Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors	-
[伍素瑩] 期刊論文	2009-07-23	Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity	-
[夏克山] 期刊論文	2009-07-23	Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice	-
[陳志豪] 期刊論文	2009-08-01	Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors	-
[李秀珠] 期刊論文	2009-08-14	Tylophorine arrests carcinoma cells at G1 phase by downregulating cyclin A2 expression	-
[陳新(2002-2015)] 期刊論文	2009-07-15	Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor	-
[謝興邦] 期刊論文	2009-04-23	Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists	-
[伍素瑩] 期刊論文	2009-06	A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.]	-
[謝興邦] 期刊論文	2009-02-26	Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity	-
[蔣維棠] 期刊論文	2009-03-15	Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors	-
[蔣維棠] 期刊論文	2009-04-01	Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors	-
[陳志豪] 期刊論文	2009-04-01	Design, synthesis, and anti-HCV activity of thiourea compounds	-
[徐祖安] 期刊論文	2009-02	Aurintricarboxylic acid inhibits influenza virus neuraminidase	-
[李秀珠] 期刊論文	2008-10-15	Analogues of 2-phenyl-ethenesulfonic acid phenyl ester have dual functions of inhibiting expression of inducible nitric oxide synthase and activating peroxisome proliferator-activated receptor gamma	-
[夏克山] 期刊論文	2008-09-21	Bioisosteric replacement of the pyrazole 3-carboxamide moiety of rimonabant. A novel series of oxadiazoles as CB1 cannabinoid receptor antagonists	-
[夏克山] 期刊論文	2008-09-11	Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor antagonists	-
[伍素瑩] 期刊論文	2008-08	A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors	-
[翁紹華] 期刊論文	2022-11	Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone	-
[李靜琪] 期刊論文	2019-03	Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors	-
[李秀珠] 期刊論文	2017-06-22	Targeting coronaviral replication and cellular JAK2 mediated dominant NF-kappaB activation for comprehensive and ultimate inhibition of coronaviral activity	-
[趙宇生(2002-2013)] 期刊論文	2015-07	Pharmacological induction of human fetal globin gene in hydroxyurea-resistant primary adult erythroid cells	-
[洪明秀] 期刊論文	2015-05	A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis	-
[葉修華] 期刊論文	2014-12-01	Morphine drives internal ribosome entry site-mediated hnRNP K translation in neurons through opioid receptor-dependent signaling	-
[李秀珠] 期刊論文	2014-08	Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells	-
[夏克山] 期刊論文	2013-11-13	Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice	-
[葉燈光] 期刊論文	2013-11	BPR0C305, an orally active microtubule-disrupting anticancer agent	-
[謝興邦] 期刊論文	2013-06-28	Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor	-
[徐祖安] 期刊論文	2013-05	Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors	-
[謝興邦] 期刊論文	2013-05	Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules	-
[李秀珠] 期刊論文	2013-06	c-Jun-mediated anti-cancer mechanisms of tylophorine	-
[葉燈光] 期刊論文	2012-12-13	Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: Exploration of the role of tylophorine e ring on biological activity	-
[岳嶽] 期刊論文	2013-02	Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems	-
[徐祖安] 期刊論文	2012-06	EGFR and myosin II inhibitors cooperate to suppress EGFR-T790M-mutant NSCLC cells	-
[徐祖安] 期刊論文	2012-01	A High-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors	-
[夏克山] 期刊論文	2012-02	Discovery of novel stem cell mobilizers that target the CXCR4 receptor	-
[徐祖安] 期刊論文	2012-01	BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML	-
[岳嶽] 期刊論文	2012-01	Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor	-
[蔣維棠] 期刊論文	2011-07	Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	-
[李靜琪] 期刊論文	2011-07-25	The first total synthesis of cytopiloyne, an anti-diabetic, polyacetylenic glucoside	-
[趙宇生(2002-2013)] 期刊論文	2011-03	Successful propagation of flavivirus infectious cDNAs by a novel method to reduce the cryptic bacterial promoter activity of virus genomes	-
[陳炯東] 期刊論文	2010-12	Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening	-
[趙宇生(2002-2013)] 期刊論文	2010-10-28	Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency	-
[趙宇生(2002-2013)] 期刊論文	2011-01	Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay	-
[趙宇生(2002-2013)] 期刊論文	2012-02	Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents	-
[趙宇生(2002-2013)] 期刊論文	2010-10	Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists	-
[趙宇生(2002-2013)] 期刊論文	2010-11	Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus	-
[趙宇生(2002-2013)] 期刊論文	2010-08	Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein	-
[夏克山] 期刊論文	2010-09	Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist	-
[洪明秀] 期刊論文	2010-10	Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities	-
[謝興邦] 期刊論文	2010-06-15	Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification	-
[謝興邦] 期刊論文	2012-09	Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization	-
[蔣維棠] 期刊論文	2012-06-07	3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	-
[黃嘯谷] 期刊論文	2013-09-11	Environmental alkylphenols modulate cytokine expression in plasmacytoid dendritic cells	-
[徐祖安] 期刊論文	2014-01-08	Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer	-
[陳志豪] 期刊論文	2017-01	A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide	-
[翁紹華] 期刊論文	2016-01	Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy	-
[謝興邦] 會議論文/會議摘要	2012-03-25	Design, synthesis, and SAR studies of duel FLT-3 and Aurora kinase inhibitors	-
[謝興邦] 會議論文/會議摘要	2013-04-07	3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor	-
[謝興邦] 會議論文/會議摘要	2013-04	Design and synthesis of Aurora kinase inhibitors as anticancer agents	-
[謝興邦] 會議論文/會議摘要	2013-04-07	Development drug candidate targeting EGFR kinase: DBPR112	-
[趙宇生(2002-2013)] 會議論文/會議摘要	2012-11	BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia	-
[謝興邦] 會議論文/會議摘要	2011-09-23	BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo	-
[謝興邦] 期刊論文	2011-09	Inhibition of HIV-1 Tat-mediated transcription by a coumarin derivative, BPRHIV001, through the Akt pathway	-
[謝興邦] 會議論文/會議摘要	2011-03-27	Design and synthesis of potent Aurora kinase inhibitors	-
[蔣維棠] 期刊論文	2011-02	Synthesis of 3,3-dimethylglutamic acid derivatives as DPP-IV inhibitors and evaluation of their chemical stability	-
[徐祖安] 期刊論文	2011-04	Isatin-beta-thiosemicarbazones as potent herpes simplex virus inhibitors	-
[趙宇生(2002-2013)] 期刊論文	2010-07	Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075	-
[趙宇生(2002-2013)] 期刊論文	2010-02-23	Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity	-
[謝興邦] 期刊論文	2010-02-25	Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives	-
[伍素瑩] 期刊論文	2009-10	(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases	-
[徐祖安] 期刊論文	2010-01	BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses	-
[謝興邦] 會議論文/會議摘要	2007-07	Anti-influenza drug discovery	-
[謝興邦] 會議論文/會議摘要	2010-08	Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models	-
[陳炯東] 期刊論文	2008-07-09	Enhanced oral bioavailability of paclitaxel by D-alpha-tocopheryl polyethylene glycol 400 succinate in mice	-
[徐祖安] 期刊論文	2008-05	Bioassay-guided purification and identification of PPARa/gamma agonists from Chlorella sorokiniana	-
[陳怡榮] 期刊論文	2008-06-01	A cell-based high-throughput screen for epidermal growth factor receptor pathway inhibitors	-
[謝興邦] 期刊論文	2008-03-01	Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold	-
[徐祖安] 期刊論文	2008-04-01	A mammalian cell-based reverse two-hybrid system for functional analysis of 3C viral protease of human enterovirus 71	-
[夏克山] 期刊論文	2008-02-07	Design, synthesis, and biological evaluation of novel alkenylthiophenes as potent and selective CB1 cannabinoid receptor antagonists	-
[李秀珠] 期刊論文	2007-11	Novel small-molecule inhibitors of transmissible gastroenteritis virus	-
[葉燈光] 期刊論文	2007-10-01	Rapid and sensitive determination of fentanyl in dog plasma by on-line solid-phase extraction integrated with a hydrophilic column coupled to tandem mass spectrometry	-
[葉燈光] 期刊論文	2007-07	Biotransformation of 6-methoxy-3-(3 ',4 ',5 '-trimethoxy-benzoyl)-1-hindole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes	-
[蔣維棠] 期刊論文	2007-03-01	3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes	-
[謝興邦] 期刊論文	2007-02-01	Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study	-
[謝興邦] 期刊論文	2006-10-19	Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists	-
[伍素瑩] 期刊論文	2006-08-24	Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease	-
[伍素瑩] 期刊論文	2006-06-15	Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies	-
[蔣維棠] 期刊論文	2006-06-15	Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors	-
[伍素瑩] 期刊論文	2006-05-04	Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities	-
[謝興邦] 期刊論文	2006-02-09	Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies	-
[蔣維棠] 期刊論文	2006-01-12	2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV	-
[謝興邦] 期刊論文	2005-12-29	Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities	-
[趙宇生(2002-2013)] 期刊論文	2004-09	Mutation in enterovirus 71 capsid protein VP1 confers resistance to the inhibitory effects of pyridyl imidazolidinone	-
[徐祖安] 期刊論文	2004-07	Inhibition of severe acute respiratory syndrome coronavirus replication by niclosamide	-
[陳炯東] 會議論文/會議摘要	2019-07	BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy	-
[謝興邦] 專利	2015-07-31	作為極光激酶抑制劑的稠合雙環嘧啶化合物	-
[謝興邦] 專利	2015-07-22	作为酪胺酸激酶抑制剂的稠合双环及多环嘧啶化合物	-
[岳嶽] 專利	2015-06-01	治療C型肝炎病毒感染之醫藥組成物	-
[陳志豪] 專利	2015-05-29	Proline derivatives	-
[謝興邦] 專利	2015-04-14	Fused multicyclic compounds as protein kinase inhibitors	-
[夏克山] 專利	2015-02-24	Pyrazole compounds	-
[夏克山] 專利	2015-02-11	吡唑類化合物	-
[夏克山] 專利	2014-11-19	咪唑-4-酮及咪唑-4-硫酮化合物	-
[謝興邦] 專利	2014-10-29	作為極光激酶抑制劑的稠合雙環嘧啶化合物	-
[謝興邦] 專利	2014-10-21	化合物於製造治療病毒感染的藥物之用途	-
[謝奉勳] 專利	2014-09-01	治療阿茲海默症或帕金森氏症之醫藥組成物	-
[葉燈光] 專利	2014-08-15	Anticancer oral formulation	-
[蔣維棠] 專利	2014-08-01	Pyrrolidine derivatives	-
[夏克山] 專利	2014-07-30	Pyrazole compounds	-
[葉燈光] 專利	2014-06-04	抗癌口服制剂	-
[蔣維棠] 專利	2014-05-12	Pyrrolidine derivatives	-
[李秀珠] 專利	2014-05-11	二苯並〔f,h〕異喹啉衍生物及其醫藥組成物	-
[蔣維棠] 專利	2014-05-08	Pyrrolidine derivatives	-
[謝興邦] 專利	2014-04-29	Quinoline compounds and their use for treating viral infection	-
[蔣維棠] 專利	2014-04-25	Pyrrolidine derivatives	-
[夏克山] 專利	2014-04-21	咪唑-4-酮及咪唑-4-硫酮化合物	-
[蔣維棠] 專利	2014-04-21	作為蛋白質激酶抑制劑之吡唑化合物及噻唑化合物、其醫藥組成物及用途	-
[李靜琪] 專利	2014-04-15	Glycoside compounds	-
[謝興邦] 專利	2014-03-20	Fused bicyclic pyrimidine compounds as aurora kinase inhibitors	-
[陳志豪] 專利	2014-03-11	脯胺酸衍生物	-
[蔣維棠] 專利	2014-02-19	Pyrrolidine derivatives	-
[蔣維棠] 專利	2013-12-18	吡咯烷化合物	-
[謝興邦] 專利	2013-11-21	治療癌症的醫藥組成物	-
[謝興邦] 專利	2013-10-01	喹啉化合物及包含其之治療病毒感染之醫藥組成物	-
[蔣維棠] 專利	2013-09-27	Pyrrolidine derivatives	-
[夏克山] 專利	2013-09-11	噻吩化合物及其醫藥組成物	-
[謝興邦] 專利	2013-08-21	Fused multicyclic compounds as protein kinase inhibitors	-
[謝興邦] 專利	2013-08-13	Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors	-
[李秀珠] 專利	2013-07-16	Dibenzo[f,h]isoquinoline derivatives	-
[謝興邦] 專利	2013-07-01	做為蛋白質激酶抑制劑之稠合多環化合物	-
[葉燈光] 專利	2013-06-05	Anticancer oral formulation	-
[蔣維棠] 專利	2013-04-30	Pyrrolidine derivatives	-
[李秀珠] 會議論文/會議摘要	2013-04-13	Exploration of the role of tylophorine E ring in anti-Coronavirus activity-Tylophorine derived dibenzoquinolines impart multi-biological activities as orally active agents	-
[陳志豪] 專利	2013-04-09	Proline derivatives	-
[謝興邦] 會議論文/會議摘要	2013-04-07	BPR000K, a novel Aurora kinase inhibitor	-
[李秀珠] 會議論文/會議摘要	2013-04	Tylophorine induces c-Jun protein accumulation through two discrete prolonged pathways NF-kappaB/PKCdelta/JNK and PI3K/PDK1/PP2A/eEF2 to promote G1 arrest in carcinoma cells	-
[李秀珠] 會議論文/會議摘要	2013-04	Identification of a quinone compound inhibits human glutaminase activity and induces autophagy in carcinoma cells	-
[夏克山] 專利	2013-03-27	Thiophene compounds	-
[蔣維棠] 專利	2013-02-11	吡咯啉啶化合物	-
[葉燈光] 專利	2013-02-11	抗癌口服藥學組成物	-
[謝興邦] 專利	2013-02-11	作為酪胺酸激酶抑制劑之稠合雙環及多環嘧啶化合物	-
[夏克山] 專利	2013-01-15	Imidazol-4-one and imidazole-4-thione compounds	-
[夏克山] 專利	2012-07-04	噻吩化合物	-
[蔣維棠] 專利	2012-06-15	Pyrrolidine derivatives	-
[謝奉勳] 專利	2012-06-12	Treatment of neurodegenerative disorders with thiourea compounds	-
[謝興邦] 專利	2012-05-11	作為極光激酶抑制劑之稠合雙環嘧啶化合物	-
[蔣維棠] 專利	2012-04-21	吡咯啉啶化合物	-
[陳志豪] 專利	2012-04-11	咪唑啉酮及咪唑啉硫酮衍生物	-
[謝興邦] 專利	2012-03-20	Fused bicyclic pyrimidine compounds as aurora kinase inhibitors	-
[陳志豪] 專利	2012-03-01	C型肝炎病毒抑制劑	-
[蔣維棠] 專利	2012-01-17	Pyrrolidine compounds	-
[謝興邦] 專利	2011-11-15	Coumarin compounds and their use for treating cancer	-
[夏克山] 專利	2011-10-01	硒吩化合物及其醫藥組成物	-
[葉燈光] 專利	2011-09-27	Formulations of indol-3-yl-2-oxoacetamide compounds	-
[蔣維棠] 專利	2011-09-20	Pyrrolidine derivatives	-
[夏克山] 專利	2011-08-11	噁二唑化合物	-
[徐祖安] 專利	2011-07-26	Hepatitis C virus inhibitors	-
[徐祖安] 專利	2011-06-21	抑制冠狀病毒之醫藥組合物	-
[徐祖安] 專利	2011-06-21	抑制冠狀病毒之醫藥組合物	-
[徐祖安] 專利	2011-06-21	抑制冠狀病毒之醫藥組合物	-
[蔣維棠] 專利	2011-05-25	Pyrrolidine derivatives	-
[陳志豪] 專利	2011-05-10	Imidazolidinone and imidazolidinethione derivatives	-
[夏克山] 專利	2011-03-21	吡唑化合物及其醫藥組成物	-
[陳志豪] 專利	2011-03-01	Thiourea derivatives	-
[謝興邦] 專利	2010-12-01	吲哚化合物	-
[謝興邦] 專利	2010-12-01	抗肿瘤化合物	-
[夏克山] 專利	2010-11-16	Thiophene compounds	-
[蔣維棠] 專利	2010-10-06	吡咯烷化合物	-
[夏克山] 專利	2010-09-28	Selenophene compounds	-
[陳志豪] 專利	2010-08-21	硫尿化合物及抑制C型肝炎病毒感染之方法	-
[夏克山] 專利	2010-04-27	Oxadiazole compounds	-
[蔣維棠] 專利	2010-03-30	Pyrrolidine compounds	-
[謝興邦] 會議論文/會議摘要	2009-09	Fast-forwarding kinase drug discovery: aurora and EGFR kinase inhibitor lead development	-
[徐祖安] 專利	2009-06-09	Treatment of coronavirus infection	-
[趙宇生(2002-2013)] 專利	2009-01-22	Pyrrolidine compounds	-
[謝興邦] 專利	2008-12-11	吲哚化合物	-
[謝興邦] 專利	2008-11-25	Anti-tumor compounds	-
[謝興邦] 專利	2008-11-11	Indole compounds	-
[蔣維棠] 專利	2008-09-16	Pyrrolidine compounds	-
[蔣維棠] 專利	2008-07-21	吡咯啉啶化合物	-
[蔣維棠] 專利	2008-07-01	Pyrrolidine compounds	-
[謝興邦] 專利	2008-05-01	抗腫瘤化合物	-
[李秀珠] 會議論文/會議摘要	2007-04-18	Identification of novel small-molecule inhibitors of transmissible gastroenteritis virus	-
[謝興邦] 會議論文/會議摘要	2005-03	Promazine analogues as potential anti SARS-CoV drugs	-
[謝興邦] 會議論文/會議摘要	2005-03	Design, synthesis and sar of indole-based PPAR agonists	-
[謝興邦] 會議論文/會議摘要	2005-03	Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents	-

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