國家衛生研究院 NHRI:作者相关文件

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"Tan, TH"的相关文件

类别	日期	题名	關聯
[譚澤華] 期刊論文	2024-11-08	Endosomes serve as signaling platforms for RIG-I ubiquitination and activation	-
[譚澤華] 會議論文/會議摘要	2024-09	The role of dual specificity phosphatase 22 (DUSP22) in rheumatoid arthritis: Mechanism and genetic investigations	-
[林文傑] 期刊論文	2024-06-14	DUSP22 inhibits lung tumorigenesis by suppression of EGFR/c-Met signaling	-
[譚澤華] 期刊論文	2024-06	UHRF1P contributes to IL-17A-mediated systemic lupus erythematosus via UHRF1-MAP4K3 axis	-
[莊懷佳] 會議論文/會議摘要	2024-05-01	Sequential regulation of Lck K63-ubiquitination and autophosphorylation by the E3 ligase UBR2 and the phosphatase DUSP22 in TCR signaling	-
[莊懷佳] 會議論文/會議摘要	2024-05-01	DUSP8 promotes IL-9 transcription by inactivating Pur-alpha leading to asthma and atopic dermatitis	-
[莊懷佳] 會議論文/會議摘要	2024-05-01	Machine learning reveals UHRF-X as a biomarker for systemic lupus erythematosus and an antagonistic protein against UHRF1 E3 ligase	-
[譚澤華] 期刊論文	2024-03-27	Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating Lck	-
[譚澤華] 期刊論文	2024-01-15	The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling	-
[林秀芳] 期刊論文	2023-12-05	Dual-specificity phosphatase 6 deficiency attenuates arterial-injury-induced intimal hyperplasia in mice	-
[譚澤華] 期刊論文	2023-11-01	DUSP8 induces TGF-beta–stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-Alpha	-
[譚澤華] 期刊論文	2023-08-22	ACE2 in chronic disease and COVID-19: Gene regulation and post-translational modification	-
[譚澤華] 專利	2023-06-11	作為用於自體免疫疾病及IL-17 相關疾病之生物標記及治療標靶之AhR-ROR-γt 複合體	-
[譚澤華] 期刊論文	2023-06	Hematopoietic progenitor kinase 1 inhibits the development and progression of pancreatic intraepithelial neoplasia	-
[譚澤華] 會議論文/會議摘要	2023-05-01	DUSP8 induces TGF-Beta-stimulated IL-9 transcription and Th9-mediated immune responses by inactivating a transcriptional repressor	-
[周文海] 期刊論文	2023-04-22	DUSP6 deficiency attenuates neurodegeneration after global cerebral ischemia	-
[莊懷佳] 期刊論文	2023-02-10	Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis	-
[譚澤華] 期刊論文	2022-07-27	SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19	-
[譚澤華] 期刊論文	2022-07-18	MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKK beta and inducing IKK beta-mediated FoxO1 nuclear export and Foxp3 downregulation	-
[陳怡榮] 期刊論文	2022-06-15	DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction	-
[譚澤華] 專利	2022-06-14	AhR-ROR-γt complex as a biomarker and therapeutic target for autoimmune disease and IL-17A-associated disease	-
[高承源] 期刊論文	2022-02-18	Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice	-
[譚澤華] 期刊論文	2022-02	Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus	-
[譚澤華] 期刊論文	2022-01	Induction of interferon-gamma and tissue inflammation by overexpression of eosinophil cationic protein in T cells and exosomes	-
[高承源] 期刊論文	2021-11-23	Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice	-
[譚澤華] 期刊論文	2021-10-25	BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus	-
[譚澤華] 期刊論文	2020-10-12	Structural insights into the active site formation of dusp22 in n-loop-containing protein tyrosine phosphatases	-
[譚澤華] 期刊論文	2020-08-12	DUSP11 attenuates lipopolysaccharide-induced macrophage activation by targeting TAK1	-
[林文傑] 期刊論文	2019-12	DUSP22 suppresses prostate cancer proliferation by targeting the EGFR-AR axis	-
[譚澤華] 期刊論文	2019-11-13	MAP4K family kinases and DUSP family phosphatases in T-Cell signaling and systemic lupus erythematosus	-
[譚澤華] 期刊論文	2019-10-22	MAP4K3/GLK in autoimmune disease, cancer and aging	-
[莊懷佳] 期刊論文	2019-10	AhR-ROR-gammat complex is a therapeutic target for MAP4K3/GLK(high)IL-17A(high) subpopulation of systemic lupus erythematosus	-
[譚澤華] 期刊論文	2019-10	MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1	-
[蘇郁文] 期刊論文	2019-07	PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency	-
[譚澤華] 期刊論文	2019-05-30	Regulation of Dual-Specificity Phosphatase (DUSP) ubiquitination and protein stability	-
[莊懷佳] 會議論文/會議摘要	2019-05	MAP4K3/GLK-induced AhR-RORyt complex is a novel therapeutic target for GLIC(high)IL-17A(high) subpopulation of SLE patients	-
[譚澤華] 會議論文/會議摘要	2019-05	T-cell signaling in Th17-mediated inflammation	-
[廖玉潔] 會議論文/會議摘要	2019-05	Control of mucosal barrier functions and gut microbiome homeostasis by DUSP6 in colitis	-
[譚澤華] 期刊論文	2019-04	MAP4K4 inhibition promotes survival of human stem cell-derived cardiomyocytes and reduces infarct size in vivo	-
[譚澤華] 期刊論文	2018-12	RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell	-
[譚澤華] 期刊論文	2018-12	Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation	-
[譚澤華] 期刊論文	2018-09-12	GLK-IKKbeta signaling induces dimerization and translocation of the AhR-RORgammat complex in IL-17A induction and autoimmune disease	-
[譚澤華] 期刊論文	2018-09-06	RBM4A-SRSF3-MAP4K4 splicing cascade constitutes a molecular mechanism for regulating brown adipogenesis	-
[蘇郁文] 期刊論文	2018-08-21	DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation	-
[莊懷佳] 圖書	2018	MAP4K3 (GLK)	-
[陳怡榮] 期刊論文	2017-11	Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration	-
[譚澤華] 專利	2017-07-19	MAP4k3 as a biomarker and therapetic target for autoimmune disease, cancer, inflammation and il-17- associated disease	-
[譚澤華] 期刊論文	2017-02	Dual-specificity phosphatase 6 deficiency regulates gut microbiome and transcriptome response against diet-induced obesity in mice	-
[譚澤華] 期刊論文	2017-01-07	MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes	-
[譚澤華] 期刊論文	2016-08	Downregulation of the phosphatase JKAP/DUSP22 in T Cells as a potential new biomarker of systemic lupus erythematosus nephritis	-
[譚澤華] 會議論文/會議摘要	2016-08	Roles of innate immune regulator TAPE in RIG-I signaling and antiviral defenses	-
[譚澤華] 會議論文/會議摘要	2016-08	Emerging roles of an innate immune regulator TAPE in Toll-like receptors, RIG-I-like receptors, and beyond	-
[蘇郁文] 會議論文/會議摘要	2016-08	Serine/threonine phosphatase PP4 is required for class switch recombination through recruitment of gammaH2AX	-
[林文傑] 會議論文/會議摘要	2016-08	Molecular mechanisms of DUSP22 ablation in enhancing EGFR-mediated lung tumor development: Potential involvement of immunosuppression	-
[譚澤華] 會議論文/會議摘要	2016-08	HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to T-cell-mediated type 2 diabetes	-
[鄒小蕙] 期刊論文	2016-07	GLK/MAP4K3 overexpression associates with recurrence risk for non-small cell lung cancer	-
[譚澤華] 期刊論文	2016-07	Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase	-
[高承源] 會議論文/會議摘要	2016-05	A multi-prong global study provides insights to gut microbiota and mucosal immunity in dusp6-deficiency conferred obesity-resistance	-
[譚澤華] 會議論文/會議摘要	2016-05	Roles of innate immune regulator TAPE in RIG-I signaling and antiviral defenses	-
[譚澤華] 會議論文/會議摘要	2016-05	Emerging roles of an innate immune regulator TAPE in Toll-like receptors, RIG-I-like receptors, and beyond	-
[譚澤華] 期刊論文	2016-03-08	Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients	-
[譚澤華] 期刊論文	2016-01	MAP4K family kinases in immunity and inflammation	-
[譚澤華] 期刊論文	2016-01	TRAF2-mediated Lys63-linked ubiquitination of DUSP14/MKP6 is essential for its phosphatase activity	-
[譚澤華] 專利	2015-12-01	絲裂原蛋白激酶激酶激酶激酶３(MAP4K3)作為自體免疫疾病、癌症、發炎及IL-17相關疾病的生物標記及治療標的	-
[譚澤華] 專利	2014-09-30	Map kinase kinase kinase kinase 3 (MAP4K3) as a biomarker and therapeutic target for autoimmune disease, cancer, inflammation and IL-17-associated disease	-
[蘇郁文] 期刊論文	2014-09-12	PP4 is essential for germinal center formation and class switch recombination in mice	-
[譚澤華] 期刊論文	2014-08-06	HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance	-
[黃慶裕] 期刊論文	2014-05-07	Protein phosphatase 4 is an essential positive regulator for Treg development, function, and protective gut immunity	-
[譚澤華] 期刊論文	2014-04-09	The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck	-
[譚澤華] 期刊論文	2014-02-15	Dual-specificity Phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation	-
[譚澤華] 期刊論文	2014-02	The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1	-
[譚澤華] 期刊論文	2013-10	Germinal center kinase-like kinase overexpression in T cells as a novel biomarker in rheumatoid arthritis	-
[蘇郁文] 期刊論文	2013-07	The serine/threonine phosphatase PP4 is required for pro-B cell development through its promotion of immunoglobulin VDJ recombination	-
[譚澤華] 期刊論文	2012-10-05	Attenuation of T cell receptor signaling by serine phosphorylation-mediated lysine 30 ubiquitination of SLP-76 protein	-
[譚澤華] 期刊論文	2012-09-14	TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity	-
[譚澤華] 期刊論文	2012-08-06	Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker	-
[黃慶裕] 期刊論文	2012-07	DUSPs, to MAP kinases and beyond	-
[譚澤華] 期刊論文	2012-07	Regulation of PKC-theta function by phosphorylation in T cell receptor signaling	-
[黃慶裕] 會議論文/會議摘要	2012-05	Defective regulatory T cells function and spontaneous colitis induced by protein phosphatase 4-deficiency	-
[譚澤華] 期刊論文	2012-03	Down-regulation of B-cell receptor signaling by hematopoietic progenitor kinase 1 (HPK1)-mediated phosphorylation and Ubiquitination of the activated B cell linker protein (BLNK)	-
[譚澤華] 期刊論文	2012-02	DUSP4 deficiency enhances CD25 expression and CD4(+) T-cell proliferation without impeding T-cell development	-
[黃慶裕] 期刊論文	2011-10	The kinase GLK controls autoimmunity and NF-kappa B signaling by activating the kinase PKC-theta in T cells	-
[譚澤華] 期刊論文	2010-02	JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration	-
[陳怡榮] 期刊論文	2006-07	Biochemical and biological characterization of a neuroendocrine-associated phosphatase	-

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