國家衛生研究院 NHRI:Items for Author

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Items for Author "Wu, SY"

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Showing 135 items.

Collection	Date	Title	Relation
[楊奕馨] 期刊論文	2024-12	Integrating predictive coding and a user-centric interface for enhanced auditing and quality in cancer registry data	-
[潘文涵] 期刊論文	2024-08-20	Is nutrient quality of the locally-existing, eAT-lancet-like plant-based diet better or worse than the average diet in Taiwan? An example of local translation	-
[其他] 期刊論文	2023-06-27	Lidocaine induces epithelial-mesenchymal transition and aggravates cancer behaviors in non-small cell lung cancer A549 cells	-
[姜乃榕] 會議論文/會議摘要	2023-06	Phase 1 studies of D07001-F4 and D07001-softgel capsule: Oral metronomic gemcitabine in subjects with advanced solid tumors	-
[潘文涵] 期刊論文	2023-04-19	Efficacy of dietary intervention with group activities on dietary intakes, frailty status, and working memory: A cluster-randomized controlled trial in community strongholds	-
[其他] 期刊論文	2023-03-09	Effect of BIM expression on the prognostic value of PD-L1 in advanced non-small cell lung cancer patients treated with EGFR-TKIs	-
[江士昇] 期刊論文	2023-02	ASO visual abstract: Distinct failure patterns in hypopharyngeal cancer patients receiving surgery-based versus radiation-based treatment	-
[江士昇] 期刊論文	2023-02	Distinct failure patterns in hypopharyngeal cancer patients receiving surgery-based versus radiation-based treatment	-
[潘文涵] 期刊論文	2022-12-07	Dietary characteristics of elders with frailty and with mild cognitive impairment: Cross-sectional findings and implications from the nutrition and health survey in Taiwan 2014-2017	-
[蕭金福] 會議論文/會議摘要	2022-11	BEAR study: A single-arm, phase II trial of BI-754091 and afatinib for refractory esophageal squamous cell carcinoma	-
[陳尚鴻] 期刊論文	2022-10-31	PD-L1 expression in high-risk early-stage colorectal cancer-its clinical and biological significance in immune microenvironment	-
[潘文涵] 期刊論文	2022-07-05	Healthy Taiwanese eating approach (TEA) toward total wellbeing and healthy Longevity	-
[江士昇] 期刊論文	2022-05-06	A new scoring system facilitating diagnosis of oral squamous malignancy on biopsy specimens	-
[翁紹華] 期刊論文	2022-02-05	Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design	-
[郭靜娟] 期刊論文	2021-08-12	Xanthine derivatives reveal an allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2)	-
[張新儀] 期刊論文	2021-08	Adequate protein intake in older adults in the context of frailty: Cross-sectional results of the Nutrition and Health Survey in Taiwan 2014-2017	-
[陳立宗] 期刊論文	2021-06-12	Phase 1b study of pegylated arginine deiminase (ADI-PEG 20) plus Pembrolizumab in advanced solid cancers	-
[張俊彥] 期刊論文	2021-06	Investigating the association between serum human papillomavirus type 16 E7 antibodies and risk of head and neck cancer	-
[姜乃榕] 會議論文/會議摘要	2021-05	A phase 2 study of liposomal irinotecan with 5-fluorouracil and leucovorin in squamous cell carcinoma of head and neck or esophagus after prior platinum-based chemotherapy or chemoradiotherapy	-
[陳立宗] 期刊論文	2021-04	Phase I dose-escalation study of SCB01A, a microtubule inhibitor with vascular disrupting activity, in patients with advanced solid tumors	-
[喻秋華] 期刊論文	2020-12	Low molecular weight fucoidan inhibits hepatocarcinogenesis and nonalcoholic fatty liver disease in zebrafish via ASGR/STAT3/HNF4A signaling	-
[其他] 期刊論文	2020-10-15	Phosphorylation of PDHA by AMPK drives TCA cycle to promote cancer metastasis	-
[張書銘] 期刊論文	2020-08	Investigating the health disparities in the association between lifestyle behaviors and the risk of head and neck cancer	-
[董國忠] 會議論文/會議摘要	2020-07	Evaluation of skin cell damage under UV exposure with FET sensors	-
[喻秋華] 期刊論文	2020-06-18	Low molecular weight fucoidan prevents radiation-induced fibrosis and secondary tumors in a zebrafish model	-
[喻秋華] 期刊論文	2020-06-01	Amino acid-modified PAMAM dendritic nanocarriers as effective chemotherapeutic drug vehicles in cancer treatment: A study using zebrafish as a cancer model	-
[張堯] 期刊論文	2020-06	EBV rta-induced IL-6 promotes migration of bystander tumor cells through IL-6R/JAK/STAT3 pathway in vitro	-
[伍素瑩] 期刊論文	2020-02-10	Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors	-
[許志成] 期刊論文	2019-12-23	Individualized home-based exercise and nutrition interventions improve frailty in older adults: A randomized controlled trial [Erratum: International Journal of Behavioral Nutrition and Physical Activity. 2019 Dec;16:Article number 119.]	-
[許志成] 期刊論文	2019-12	Individualized home-based exercise and nutrition interventions improve frailty in older adults: A randomized controlled trial	-
[蔣維棠] 期刊論文	2019-12	Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia	-
[謝興邦] 期刊論文	2019-11-27	Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer	-
[葉燈光] 會議論文/會議摘要	2019-10	Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer	-
[張書銘] 期刊論文	2019-06	Validation of alcohol flushing questionnaire to identify ALDH2 status in a case-control study of head and neck cancer	-
[莊紹源] 期刊論文	2019-05	Dietary patterns and foods associated with cognitive function in Taiwanese older adults: The cross-sectional and longitudinal studies	-
[伍素瑩] 期刊論文	2019-04-10	Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants	-
[張書銘] 期刊論文	2019-04	Oral hygiene and the overall survival of head and neck cancer patients	-
[張書銘] 期刊論文	2019-02	The influence of prediagnosis alcohol consumption and the polymorphisms of ethanol metabolizing genes on the survival of head and neck cancer patients	-
[許志成] 期刊論文	2018-09	Dietary education with customised dishware and food supplements can reduce frailty and improve mental well-being in elderly people: A single-blind randomized controlled study	-
[張書銘] 期刊論文	2018-06	The interplay between oral microbiome, lifestyle factors, and genetic polymorphisms in the risk of oral squamous cell carcinoma	-
[張光裕] 會議論文/會議摘要	2018-05	A phase Ib study of ADI-PEG 20 plus pembrolizumab in advanced solid cancers	-
[翁紹華] 期刊論文	2018-04	4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy	-
[喻秋華] 期刊論文	2018-02	Radiation-sensitive dendrimer-based drug delivery system	-
[張書銘] 期刊論文	2017-10-24	Investigating the association between diet and risk of head and neck cancer in Taiwan	-
[張書銘] 期刊論文	2017-08-29	Investigating the association between alcohol and risk of head and neck cancer in Taiwan	-
[其他] 期刊論文	2017-06	Depression and self-care maintenance in patients with heart failure: A moderated mediation model of self-care confidence and resilience	-
[岳嶽] 期刊論文	2017-06	Mutagenesis of dengue virus protein NS2A revealed a novel domain responsible for virus-induced cytopathic effect and interactions between NS2A and NS2B transmembrane segments	-
[姜乃榕] 期刊論文	2017-05	A phase I dose escalation study of SCBO1A, a micro tubular inhibitor with vascular disrupting activity, in patients with advanced solid tumors refractory to standard therapy	-
[張書銘] 期刊論文	2017-04-21	Regular recreational physical activity and risk of head and neck cancer	-
[洪明秀] 會議論文/會議摘要	2016-12	Phenyl benzenesulfonylhydrazides: Selective indoleamine 2,3-dioxygenase inhibitors with potent in vivo pharmacodynamic activity and antitumor efficacy	-
[張書銘] 期刊論文	2016-10-25	A comprehensive analysis on the association between tobacco-free Betel Quid and risk of Head and Neck Cancer in Taiwanese men	-
[張書銘] 期刊論文	2016-09	Allergy symptoms, serum total immunoglobulin E, and risk of head and neck cancer	-
[伍素瑩] 期刊論文	2016-04-12	Pyrazolylamine derivatives reveal the conformational switching between type I and type II binding modes of Anaplastic Lymphoma Kinase (ALK)	-
[伍素瑩] 期刊論文	2016-01	Important hydrogen bond networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) inhibitor design revealed by crystal structures of imidazoleisoindole derivatives with IDO1	-
[翁紹華] 期刊論文	2016-01	Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy	-
[伍素瑩] 期刊論文	2015-10	Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening	-
[謝興邦] 專利	2015-07-31	作為極光激酶抑制劑的稠合雙環嘧啶化合物	-
[褚志斌] 期刊論文	2015-07	CR3 and Dectin-1 collaborate in macrophage cytokine response through association on lipid rafts and activation of Syk-JNK-AP-1 pathway	-
[張俊彥] 期刊論文	2015-07	Alcohol drinking obliterates the inverse association between serum retinol and risk of head and neck cancer	-
[其他] 期刊論文	2015-06-17	The ZNF304-integrin axis protects against anoikis in cancer	-
[洪文俊] 期刊論文	2015-03-25	Ras induces experimental lung metastasis through up-regulation of RbAp46 to suppress RECK promoter activity	-
[張書銘] 期刊論文	2015-03	Genetic polymorphisms in the prostaglandin pathway genes and risk of head and neck cancer	-
[張書銘] 期刊論文	2014-11	The interplay between alcohol consumption, oral hygiene, ALDH2 and ADH1B in the risk of head and neck cancer	-
[謝興邦] 專利	2014-10-29	作為極光激酶抑制劑的稠合雙環嘧啶化合物	-
[張書銘] 期刊論文	2014-10-24	Comparison of concurrent chemoradiotherapy versus neoadjuvant chemotherapy followed by radiation in patients with advanced nasopharyngeal carcinoma in endemic area: experience of 128 consecutive cases with 5year follow-up	-
[蘇益仁(2002-2015)] 期刊論文	2014-09	Autophagy-preferential degradation of MIR224 participates in hepatocellular carcinoma tumorigenesis	-
[翁紹華] 期刊論文	2014-08	Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors	-
[張書銘] 期刊論文	2014-05-05	Tea consumption and risk of head and neck cancer	-
[謝興邦] 專利	2014-03-20	Fused bicyclic pyrimidine compounds as aurora kinase inhibitors	-
[張光裕] 期刊論文	2013-10	Investigating the association between oral hygiene and head and neck cancer	-
[張俊彥] 期刊論文	2013-09	Furanylazaindoles: Potent anticancer agents in vitro and in vivo	-
[蘇益仁(2002-2015)] 期刊論文	2013-08	Autophagy suppresses tumorigenesis of hepatitis B virus-associated hepatocellular carcinoma through degradation of microRNA-224	-
[蘇益仁(2002-2015)] 期刊論文	2013-07	WW domain-containing oxidoreductase is involved in upregulation of matrix metalloproteinase 9 by Epstein-Barr virus latent membrane protein 2A	-
[楊采菱] 期刊論文	2013-06	Identification of a novel antimicrobial peptide from human hepatitis B virus core protein arginine-rich domain (ARD)	-
[張書銘] 會議論文/會議摘要	2013-06	Oral hygiene and risk of head and neck cancer	-
[謝興邦] 期刊論文	2013-05	Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules	-
[徐祖安] 期刊論文	2013-05	Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors	-
[張俊彥] 期刊論文	2013-02-01	Allergies and risk of head and neck cancer: An original study plus meta-analysis	-
[岳嶽] 期刊論文	2013-02	Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems	-
[張堯] 期刊論文	2013-02	Epstein-Barr virus Zta upregulates matrix metalloproteinases 3 and 9 that synergistically promote cell invasion in vitro	-
[徐祖安] 期刊論文	2012-08	Development of an anti-influenza drug screening assay targeting nucleoproteins with tryptophan fluorescence quenching	-
[潘秀玲(2009-2013)] 期刊論文	2012-07	Physalin F induces cell apoptosis in human renal carcinoma cells by targeting NF-kappaB and generating reactive oxygen species	-
[張堯] 期刊論文	2012-06	Epstein-Barr virus latent membrane protein 2A promotes invasion of nasopharyngeal carcinoma cells through ERK/Fra-1-mediated induction of matrix metalloproteinase 9	-
[陳炯東] 會議論文/會議摘要	2012-06	Involvement of transcriptional regulator Ndt80 in stress responses of Candida albicans	-
[謝興邦] 專利	2012-05-11	作為極光激酶抑制劑之稠合雙環嘧啶化合物	-
[于重元] 期刊論文	2012-05	The HPV E6 oncoprotein targets histone methyltransferases for modulating specific gene transcription	-
[謝興邦] 專利	2012-03-20	Fused bicyclic pyrimidine compounds as aurora kinase inhibitors	-
[夏克山] 期刊論文	2012-02	Discovery of novel stem cell mobilizers that target the CXCR4 receptor	-
[蔣維棠] 專利	2012-01-17	Pyrrolidine compounds	-
[朱清良(2005-2010)] 期刊論文	2011-11	Immunization with apoptotic phagocytes containing histoplasma capsulatum activates functional CD8(+) T cells to protect against histoplasmosis	-
[張俊彥] 期刊論文	2011-09	Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents	-
[張堯] 期刊論文	2011-07	Epstein-Barr virus Zta-Induced immunomodulators from nasopharyngeal carcinoma cells upregulate interleukin-10 production from monocytes	-
[謝興邦] 期刊論文	2011-04-28	Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents	-
[陳炯東] 期刊論文	2010-12	Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening	-
[蔣維棠] 專利	2010-10-06	吡咯烷化合物	-
[趙宇生(2002-2013)] 期刊論文	2010-10	Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists	-
[張堯] 期刊論文	2010-09	Endogenous latent membrane protein 1 in Epstein-Barr virus-infected nasopharyngeal carcinoma cells attracts T lymphocytes through upregulation of multiple chemokines	-
[張俊彥] 期刊論文	2010-09	Cancer cells acquire mitotic drug resistance properties through beta i-tubulin mutations and alterations in the expression of beta-tubulin isotypes	-
[謝興邦] 會議論文/會議摘要	2010-08	Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models	-
[謝興邦] 期刊論文	2010-06-15	Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification	-
[蔣維棠] 專利	2010-03-30	Pyrrolidine compounds	-
[張俊彥] 期刊論文	2010-03-11	5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors	-
[謝興邦] 期刊論文	2010-02-01	Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor	-
[伍素瑩] 期刊論文	2009-10	(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases	-
[謝興邦] 期刊論文	2009-08-13	Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach	-
[伍素瑩] 期刊論文	2009-07-23	Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity	-
[伍素瑩] 期刊論文	2009-06	A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.]	-
[張堯] 期刊論文	2009-05-15	Endoplasmic reticulum stress triggers XBP-1-mediated up-regulation of an EBV oncoprotein in nasopharyngeal carcinoma	-
[謝興邦] 期刊論文	2009-04-23	Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists	-
[謝興邦] 會議論文/會議摘要	2009-03	Discovery and development of novel furano-pyrimidine analogs as Aurora kinase inhibitors	-
[謝興邦] 期刊論文	2009-02-26	Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity	-
[趙宇生(2002-2013)] 專利	2009-01-22	Pyrrolidine compounds	-
[謝興邦] 期刊論文	2008-12-25	Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents	-
[伍素瑩] 期刊論文	2008-08	A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors	-
[蔣維棠] 專利	2008-07-21	吡咯啉啶化合物	-
[蔣維棠] 專利	2008-07-01	Pyrrolidine compounds	-
[張堯] 期刊論文	2008-04	Epstein-Barr virus lytic transactivator Zta enhances chemotactic activity through induction of interleukin-8 in nasopharyngeal carcinoma cells	-
[謝興邦] 期刊論文	2008-03-01	Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold	-
[伍素瑩] 期刊論文	2008	Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases	-
[伍素瑩] 會議論文/會議摘要	2007	Crystal structures and computer screened inhibitors of Helicobacter pylori undecaprenyl pyrophosphate synthase	-
[謝興邦] 期刊論文	2006-10-19	Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists	-
[伍素瑩] 期刊論文	2006-08-24	Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease	-
[張堯] 期刊論文	2006-08	Induction of the early growth response 1 gene by Epstein-Barr virus lytic transactivator Zta	-
[伍素瑩] 期刊論文	2006-06-15	Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies	-
[伍素瑩] 期刊論文	2006-05-04	Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities	-
[謝興邦] 期刊論文	2006-02-09	Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies	-
[蔣維棠] 期刊論文	2006-01-12	2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV	-
[謝興邦] 期刊論文	2005-12-29	Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities	-
[伍素瑩] 期刊論文	2005-12-15	The effect of N-terminal truncation on double-dimer assembly of goose delta-crystallin	-
[蔣維棠] 期刊論文	2005-07-01	Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors	-
[謝興邦] 會議論文/會議摘要	2005-03	Design, synthesis and sar of indole-based PPAR agonists	-
[謝興邦] 會議論文/會議摘要	2005-03	Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents	-
[周玉山(1996-2005)] 期刊論文	2002-01	Association between markers in chromosomal region 17q23 and young onset hypertension: a TDT study	-
[周玉山(1996-2005)] 會議論文/會議摘要	2000-10	Markers of lipoprotein lipase and angiotensin I converting enzyme are linked to young-onset hypertension in Taiwan	-
[周玉山(1996-2005)] 期刊論文	2000-09	Linkage analysis with candidate genes: the Taiwan young-onset hypertension genetic study	-

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Items for Author "Wu, SY"