| [石全(2014-2017)] 會議論文/會議摘要 |
2020-08 |
BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification |
- |
|
| [翁紹華] 會議論文/會議摘要 |
2019-07 |
Use of integrated genomic analyses in patient-derived tumor model to discover new clinical indications for the multikinase inhibitor drug candidate, DBPR216 |
- |
|
| [陳炯東] 會議論文/會議摘要 |
2019-07 |
BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy |
- |
|
| [紀雅惠] 會議論文/會議摘要 |
2019-07 |
An Aurora kinase inhibitor BPR6K471 inhibits tumor growth and reduces the cancer stem cell-like properties of small cell lung cancer |
- |
|
| [其他] 會議論文/會議摘要 |
2019-05 |
Assessment of photodynamic therapy (PDT) efficacy of X-ray activated nanoscintillators using F-18-HT in PET |
- |
|
| [翁紹華] 會議論文/會議摘要 |
2018-07 |
4-Bromophenylhydrazinyl benzenesulfonylphenylureas inhibit indoleamine 2,3-dioxygenase in vitro and in vivo |
- |
|
| [葉燈光] 會議論文/會議摘要 |
2017-04 |
Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation |
- |
|
| [楊重熙] 會議論文/會議摘要 |
2016-05 |
In Vivo PET/CT neuroimaging of radiolabeled nanocarriers following intranasal drug delivery (INDD): Validation using Ex Vivo PET/CT, gamma counting and autoradiography |
- |
|
| [羅履維] 會議論文/會議摘要 |
2016-05 |
Experimental model validation for x-ray induced luminescence imaging in tissue phantoms with europium-doped nanophosphors |
- |
|
| [郭書辰] 期刊論文 |
2015-08 |
Risk factors and outcome for colistin resistant acinetobacter nosocomialis bacteraemia in patients without previous colistin exposure |
- |
|
| [陳炯東] 會議論文/會議摘要 |
2014-10 |
YYEI motif is critical to oncogenicity of 14-3-3 proteins |
- |
|
| [謝興邦] 會議論文/會議摘要 |
2014-10 |
Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma |
- |
|
| [葉燈光] 專利 |
2014-08-15 |
Anticancer oral formulation |
- |
|
| [葉燈光] 專利 |
2014-06-04 |
抗癌口服制剂 |
- |
|
| [羅履維] 圖書 |
2014-03 |
Silica nanoparticle platform |
- |
|
| [徐祖安] 會議論文/會議摘要 |
2014-03 |
DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study |
- |
|
| [羅履維] 會議論文/會議摘要 |
2013-09-08 |
Nanoparticle-programmed self-destructive neural stem cells for targeted glioblastoma therapy |
- |
|
| [葉燈光] 專利 |
2013-06-05 |
Anticancer oral formulation |
- |
|
| [謝興邦] 會議論文/會議摘要 |
2013-04-07 |
BPR000K, a novel Aurora kinase inhibitor |
- |
|
| [葉燈光] 專利 |
2013-02-11 |
抗癌口服藥學組成物 |
- |
|
| [羅履維] 會議論文/會議摘要 |
2012-03-25 |
Biocompatible gold nanomaterials for optoacoustic imaging (OAI) |
- |
|
| [葉燈光] 專利 |
2011-09-27 |
Formulations of indol-3-yl-2-oxoacetamide compounds |
- |
|
| [陳炯東] 專利 |
2010-05-11 |
咪唑胺化合物 |
- |
|
| [陳志豪] 專利 |
2010-05-11 |
咪唑啉酮化合物 |
- |
|
| [陳炯東] 專利 |
2010-04-21 |
吲哚-3-基-2-氧乙醯胺衍生物之新化合物及其醫藥組合物與製備方法 |
- |
|
| [陳淑貞(1998-2001)] 專利 |
2010-02-16 |
Methods of 1H-indol-3-yl-2-oxoacetamide compounds |
- |
|
| [蕭子凱(2001-2004)] 專利 |
2009-08-21 |
一種定量迦瑪射線能量、高峰時間及衰減時間常數的裝置及其使用方法 |
- |
|
| [陳炯東] 專利 |
2009-08-04 |
Imidazolamino compounds |
- |
|
| [蕭子凱(2001-2004)] 專利 |
2009-06-19 |
A device and method for digitizing pet radiation events |
- |
|
| [蕭子凱(2001-2004)] 專利 |
2009-03-19 |
A device and method for digitizing gamma ray energy and characterizing peak time and decay time constant without the use of ADC |
- |
|
| [陳志豪] 專利 |
2009-03-10 |
Imidazolidinone compounds |
- |
|
| [蕭子凱(2001-2004)] 專利 |
2009-01-02 |
A device and method for digitizing gamma ray energy and characterizing peak time and decay time constant without the use Of ADC |
- |
|
| [陳炯東] 專利 |
2008-12-09 |
Imidazolamino compounds |
- |
|
| [陳炯東] 專利 |
2008-07-08 |
Use of 1H-indol-3-yl-2-oxoacetamide compounds |
- |
|
| [蕭子凱(2001-2004)] 專利 |
2008-03-11 |
Device and method for digitizing PET radiation events |
- |
|
| [陳志豪] 專利 |
2007-06-01 |
咪唑啉酮化合物 |
- |
|
| [蕭子凱(2001-2004)] 專利 |
2007-04-03 |
Device and method for digitizing gamma ray energy and characterizing peak time and decay time constant without the use of ADC |
- |
|
| [蕭子凱(2001-2004)] 專利 |
2007-02-11 |
一種數位化正子斷層掃瞄發射裝置及其使用方法 |
- |
|
| [其他] 會議論文/會議摘要 |
2007 |
A system model for pinhole SPECT simulating edge penetration, detector and pinhole response and non-uniform attenuation |
- |
|
| [陳志豪] 專利 |
2006-10-31 |
Imidazolidinone compounds |
- |
|
| [陳炯東] 專利 |
2006-09-19 |
Imidazolamino compounds |
- |
|
| [陳炯東] 專利 |
2005-03-01 |
一種用以抑制癌細胞之醫藥組合物 |
- |
|
| [謝興邦] 會議論文/會議摘要 |
2005-03 |
Design, synthesis and sar of indole-based PPAR agonists |
- |
|
| [謝興邦] 會議論文/會議摘要 |
2005-03 |
Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents |
- |
|
| [李秀珠] 會議論文/會議摘要 |
2004-07 |
Drug design for BPR0L075 as an anticancer agent |
- |
|
| [陳炯東] 會議論文/會議摘要 |
2004 |
Acellular biological tissues loaded with a novel angiogenic agent (ginsenoside Rg1) as a tissue-engineering extracellular matrix |
- |
|
| [陳炯東] 期刊論文 |
2001-06 |
Time- and concentration-dependent penetration of doxorubicin in prostate tumors |
- |
 |
| [陳炯東] 會議論文/會議摘要 |
2002-03 |
Sympathoinhibitory action of nociceptin in the rat spinal cord |
- |
|
| [彭汪嘉康(1996-2007)] 期刊論文 |
2002-05 |
Phase II and pharmacokinetic study of GL331 in previously treated Chinese gastric cancer patients |
- |
|
| [陳炯東] 期刊論文 |
2003-04-24 |
Synthesis and biological evaluation of N-heterocyclic indolyl glyoxylamides as orally active anticancer agents |
- |
|
| [周玉山(1996-2005)] 期刊論文 |
2004-03-19 |
Diverse cellular transformation capability of overexpressed genes in human hepatocellular carcinoma |
- |
|
| [陳炯東] 期刊論文 |
2004-02 |
A simple quantitative method for evaluation of angiogenesis activity |
- |
|
| [張俊彥] 期刊論文 |
2004-07-01 |
BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo |
- |
|
| [陳炯東] 期刊論文 |
2004-08-10 |
Inhibition of human vascular endothelial cells proliferation by terbinafine |
- |
|
| [陳炯東] 期刊論文 |
2004-04 |
Central pressor effects of CART peptides in anesthetized rats |
- |
|
| [陳炯東] 期刊論文 |
2005-03 |
Preparation of nanoparticles composed of chitosan/poly-gamma-glutamic acid and evaluation of their permeability through Caco-2 cells |
- |
|
| [陳炯東] 期刊論文 |
2005-04 |
A natural compound (ginsenoside Re) isolated from Panax ginseng as a novel angiogenic agent for tissue regeneration |
- |
|
| [陳炯東] 期刊論文 |
2005-05 |
Loading of a novel angiogenic agent, ginsenoside Rg(1) in an acellular biological tissue for tissue regeneration |
- |
|
| [蕭子凱(2001-2004)] 期刊論文 |
2005-08 |
A new approach for pulse processing in positron emission tomography |
- |
|
| [謝興邦] 期刊論文 |
2005-12-29 |
Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities |
- |
|
| [蔣維棠] 期刊論文 |
2006-01-12 |
2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV |
- |
|
| [陳炯東] 期刊論文 |
2006-03 |
Paclitaxel-loaded poly(gamma-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system for the treatment of liver cancer |
- |
|
| [陳炯東] 期刊論文 |
2006-03 |
Paclitaxel-loaded poly(gamma-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system against cultured HepG2 cells |
- |
|
| [伍素瑩] 期刊論文 |
2006-05-04 |
Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities |
- |
|
| [蔣維棠] 期刊論文 |
2006-06-15 |
Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors |
- |
|
| [陳炯東] 期刊論文 |
2006-08 |
Impaired phagocytosis of capsular serotypes K1 or K2 Klebsiella pneumoniae in type 2 diabetes mellitus patients with poor glycemic control |
- |
|
| [葉燈光] 期刊論文 |
2006-11-25 |
The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes |
- |
|
| [陳炯東] 期刊論文 |
2006-12 |
Pharmacokinetics of anti-SARS-CoV agent niclosamide and its analogs in rats |
- |
|
| [陳炯東] 期刊論文 |
2007-01 |
Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery |
- |
|
| [謝興邦] 期刊論文 |
2007-02-01 |
Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study |
- |
|
| [蔣維棠] 期刊論文 |
2007-03-01 |
3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes |
- |
|
| [陳炯東] 期刊論文 |
2007-03-14 |
Novel nanoparticles for oral insulin delivery via the paracellular pathway |
- |
|
| [陳炯東] 期刊論文 |
2007-03 |
Effects of paclitaxel and doxorubicin in histocultures of hepatocelular carcinomas |
- |
|
| [其他] 期刊論文 |
2007-05 |
An automatic MRI/SPECT registration algorithm using image intensity and anatomical feature as matching characters: application on the evaluation of Parkinson's disease |
- |
|
| [葉燈光] 期刊論文 |
2007-07 |
Biotransformation of 6-methoxy-3-(3 ',4 ',5 '-trimethoxy-benzoyl)-1-hindole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes |
- |
|
| [葉燈光] 期刊論文 |
2008-02-28 |
Shengmai San reduces hepatic lipids and lipid peroxidation in rats fed on a high-cholesterol diet |
- |
|
| [黃秀芬] 期刊論文 |
2008-03 |
Decreased expression of UK114 is related to the differentiation status of human hepatocellular carcinoma |
- |
|
| [陳炯東] 期刊論文 |
2008-06 |
Oral delivery of peptide drugs using nanoparticles self-assembled by poly(gamma-glutamic acid) and a chitosan derivative functionalized by trimethylation |
- |
|
| [陳炯東] 期刊論文 |
2008-07-09 |
Enhanced oral bioavailability of paclitaxel by D-alpha-tocopheryl polyethylene glycol 400 succinate in mice |
- |
|
| [陳炯東] 期刊論文 |
2008-09 |
Human breast tumor cells express multimodal imaging reporter genes |
- |
|
| [夏克山] 期刊論文 |
2015-03 |
Stem cell mobilizers targeting chemokine receptor CXCR4: Renoprotective application in acute kidney injury |
- |
|
| [李秀珠] 會議論文/會議摘要 |
2004-09 |
Drug design of BPR0L075 as an anticancer agent |
- |
|
| [其他] 期刊論文 |
1998-10 |
Characterization of p96(h2bk): Immunoreaction with an anti-Erk (extracellular-signal-regulated kinase) peptide antibody and activity in Xenopus oocytes and eggs |
- |
|
| [莊聲宏(1997-2004)] 期刊論文 |
2004-03 |
Expression of cytoplasmic-domain substituted epidermal growth factor receptor inhibits tumorigenicity of EGFR-overexpressed human glioblastoma multiforme |
- |
|
| [梁賡義] 期刊論文 |
2007-08 |
A randomised placebo-controlled trial of a traditional chinese herbal formula in the treatment of primary dysmenorrhoea |
- |
|
| [謝興邦] 會議論文/會議摘要 |
2006-09 |
MEDI 416-3- 2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino -3-methyl-butyr amide analogs as DPP-IV inhibitors for the treatment of type-II diabetes |
- |
|
| [謝興邦] 會議論文/會議摘要 |
2010-08 |
Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models |
- |
|
| [張文祥] 會議論文/會議摘要 |
2004 |
ALA-mediated photodynamic therapy decreases the ability of cellular invasion in CL1-5 human lung adenocarcinoma cells |
- |
|
| [張文祥] 會議論文/會議摘要 |
2004 |
ALA-mediated photodynamic therapy decreases the ability of cellular invasion in CL1-5 human lung adenocarcinoma cells |
- |
|
| [涂醒哲(2003-2004)] 期刊論文 |
2005-03 |
SARS in Taiwan: an overview and lessons learned |
- |
|
| [羅秀容] 期刊論文 |
2006-07 |
Non-lethal Candida albicans cph1/cph1 efg1/efg1 transcription factor mutant establishing restricted zone of infection in a mouse model of systemic infection |
- |
|
| [其他] 期刊論文 |
2007-06 |
Improved accuracy of brain MRI/SPECT registration using a two-cluster SPECT normalization algorithm and a combinative similarity measure: application to the evaluation of Parkinson's disease |
- |
|
| [伍素瑩] 期刊論文 |
2009-10 |
(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases |
- |
|
| [蔡世峯] 期刊論文 |
2010-02-09 |
ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway |
- |
|
| [趙宇生(2002-2013)] 期刊論文 |
2010-07 |
Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075 |
- |
|
| [林名釗] 期刊論文 |
2010-10 |
RU486-inducible recombination in the salivary glands of lactoferrin promoter-driven green fluorescent Cre transgenic mice |
- |
|
| [其他] 會議論文/會議摘要 |
2006-10 |
New ray-driven system matrix for small-animal pinhole-SPECT with detector blur, geometric response and edge penetration modeling |
- |
|
| [陳炯東] 期刊論文 |
2011-05 |
Quercetin and rutin reduced the bioavailability of cyclosporine from Neoral, an immunosuppressant, through activating P-glycoprotein and CYP 3A4 |
- |
|
| [謝興邦] 會議論文/會議摘要 |
2011-03-27 |
Design and synthesis of potent Aurora kinase inhibitors |
- |
|
| [陳炯東] 期刊論文 |
2011-10 |
Antiproliferative effects of N-heterocyclic indolyl glyoxylamide derivatives on human lung cancer cells |
- |
|
| [林嬪嬪] 期刊論文 |
2012-01 |
Mitochondrial apoptosis and FAK signaling disruption by a novel histone deacetylase inhibitor, HTPB, in antitumor and antimetastatic mouse models |
- |
|
| [陳炯東] 會議論文/會議摘要 |
2012-06 |
Involvement of transcriptional regulator Ndt80 in stress responses of Candida albicans |
- |
|
| [陳炯東] 會議論文/會議摘要 |
2011-09 |
Effects of dipeptidyl peptidase 4 inhibition with MK-0431 on syngeneic mouse islet transplantation |
- |
|
| [趙宇生(2002-2013)] 會議論文/會議摘要 |
2012-11 |
BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia |
- |
|
| [陳炯東] 期刊論文 |
2013-07 |
Andrographis paniculata extract and andrographolide modulate the hepatic drug metabolism system and plasma tolbutamide concentrations in rats |
- |
|
| [謝興邦] 會議論文/會議摘要 |
2013-04-07 |
Development drug candidate targeting EGFR kinase: DBPR112 |
- |
|
| [謝興邦] 會議論文/會議摘要 |
2013-04 |
Design and synthesis of Aurora kinase inhibitors as anticancer agents |
- |
|
| [葉燈光] 會議論文/會議摘要 |
2013-11 |
A development drug candidate targeting EGFR kinase for lung cancer: DBPR112 |
- |
|
| [羅履維] 期刊論文 |
2014-08-07 |
Significant inhibition of tumor growth following single dose nanoparticle-enhanced photodynamic therapy |
- |
|
| [羅履維] 期刊論文 |
2014-11 |
Radioluminescence characterization of in situ x-ray nanodosimeters: Potential real-time monitors and modulators of external beam radiation therapy |
- |
|
| [謝興邦] 會議論文/會議摘要 |
2014-11 |
Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent |
- |
|
| [羅履維] 會議論文/會議摘要 |
2015-05 |
Evaluation of X-ray fuorescence emission tomography for real-time assessment of photodynamic therapy effect |
- |
|
| [羅履維] 會議論文/會議摘要 |
2014-05 |
Direct x-ray luminescence tomography using selective plane illumination |
- |
|
| [羅履維] 會議論文/會議摘要 |
2014-05 |
Nanoparticle-engineered probing of neural stem cells targeted therapy for glioblastoma |
- |
|
| [陳炯東] 會議論文/會議摘要 |
2015-08 |
Zinc-dipicolylamine directed pharmaceutical delivery system (ZAPS) as an innovative cancer drug delivery platform |
- |
|
| [陳炯東] 會議論文/會議摘要 |
2016-12 |
Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST |
- |
|
| [陳炯東] 會議論文/會議摘要 |
2016-08 |
Dipeptidyl peptidase-4 inhibitor LAF-237 improves glucose tolerance and expends graft beta cell mass in diabetic mice transplanted with a sufficient number of islets |
- |
|
| [羅履維] 期刊論文 |
2017-09 |
Rapid measurement of fluorescence lifetimes using SiPM detection and waveform sampling |
- |
|
| [陳炯東] 會議論文/會議摘要 |
2016-10 |
Multifunctional nanoparticles for oral protein drug delivery |
- |
|
| [陳炯東] 會議論文/會議摘要 |
2018-01 |
Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer |
- |
|
| [郭書辰] 期刊論文 |
2018-05 |
Biofilm formation is not associated with worse outcome in Acinetobacter baumannii bacteraemic pneumonia |
- |
|
| [陳炯東] 會議論文/會議摘要 |
2015-08 |
Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia |
- |
|
| [陳炯東] 會議論文/會議摘要 |
2011-05 |
Study of glioblastoma multiforme metastatic and invasive mechanism by polycistronic imaging probe in tumor implanted animal model |
- |
|
| [徐祖安] 會議論文/會議摘要 |
2018-12 |
Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer |
- |
|
| [徐祖安] 會議論文/會議摘要 |
2018-12 |
Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer |
- |
|
| [羅履維] 期刊論文 |
2019-04 |
Highly sensitive electron paramagnetic resonance nanoradicals for quantitative intracellular tumor oxymetric images |
- |
|
| [陳炯東] 期刊論文 |
2019-07 |
Citronellol induces necroptosis of human lung cancer cells via TNF-alpha pathway and reactive oxygen species accumulation |
- |
|
| [顏婉菁] 會議論文/會議摘要 |
2019-10 |
Inhibition of Rspo-Wnt pathway facilitates checkpoint blockade therapy by anti-RSPO3 antibody (DBPR117) |
- |
|
| [蔣維棠] 期刊論文 |
2019-12 |
Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia |
- |
|
| [陳炯東] 期刊論文 |
2021-08 |
A noninvasive gut-to-brain oral drug delivery system for treating brain tumors |
- |
|
| [陳炯東] 期刊論文 |
2021-10-01 |
Engineering nano- and microparticles as oral delivery vehicles to promote intestinal lymphatic drug transport |
- |
|
| [余冠儀] 期刊論文 |
2022-05-02 |
Furin and TMPRSS2 resistant spike induces robust humoral and cellular immunity against SARS-CoV-2 lethal infection |
- |
|
| [夏克山] 期刊論文 |
2022-10-03 |
Protective effect of CXCR4 antagonist DBPR807 against ischemia-reperfusion injury in a rat and porcine model of myocardial infarction: Potential adjunctive therapy for percutaneous coronary intervention |
- |
|
| [羅履維] 期刊論文 |
2023-06-02 |
Illuminating and radiosensitizing tumors with 2DG-bound gold-based nanomedicine for targeted CT imaging and therapy |
- |
|
| [陳炯東] 期刊論文 |
2011-11 |
Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins |
- |
|
| [謝興邦] 期刊論文 |
2019-11-27 |
Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer |
- |
|
| [李秀珠] 期刊論文 |
2020-12-14 |
Inhibition of SARS-CoV-2 by highly potent broad-spectrum anti-coronaviral tylophorine-based derivatives |
- |
|
| [謝興邦] 期刊論文 |
2021-10-14 |
Discovery of BPR1R024, an orally active and selective CSF1R inhibitor that exhibits antitumor and immunomodulatory activity in a murine colon tumor model |
- |
|
| [鄒倫] 期刊論文 |
2022-06-21 |
Synthesis and evaluation of small molecule drug conjugates harnessing thioester-linked maytansinoids |
- |
|
| [蕭金福] 期刊論文 |
2012-09 |
Design and evaluation of multiregional trials with heterogeneous treatment effect across regions |
- |
|
| [鄒小蕙] 期刊論文 |
2017-09 |
A tolerance interval approach to assessing the biosimilarity of follow-on biologics |
- |
|
| [羅履維] 期刊論文 |
2010-08 |
Tri-functionalization of mesoporous silica nanoparticles for comprehensive cancer theranostics-the trio of imaging, targeting and therapy |
- |
|
| [林名釗] 圖書 |
2003 |
Functional and molecular imaging using positron emission tomography |
- |
|
| [蕭金福] 圖書 |
2018-08-21 |
Design and data analysis of multiregional clinical trials (MRCTs)—Theory and practice |
- |
|
| [蕭金福] 會議論文/會議摘要 |
2016-11-11 |
Assessing benefit and consistency of treatment effect under a discrete random effects model in multiregional clinical trials |
- |
|
| [陳炯東] 期刊論文 |
2010-11 |
Do neutrophils play a role in establishing liver abscesses and distant metastases caused by Klebsiella pneumoniae? |
- |
|
| [蕭樑基] 期刊論文 |
2011-07 |
Immune response and pathophysiological features of Klebsiella pneumoniae liver abscesses in an animal model |
- |
|
| [羅履維] 期刊論文 |
2012-12 |
Recent advances in nanoparticle-based föster resonance energy transfer for biosensing, molecular imaging and drug release profiling |
- |
|
| [羅履維] 期刊論文 |
2013-07 |
Theranostic applications of mesoporous silica nanoparticles and their organic/inorganic hybrids |
- |
|
| [陳炯東] 期刊論文 |
2012-04 |
Securin enhances the anti-cancer effects of 6-Methoxy-3-(3′,4′,5′-Trimethoxy-Benzoyl)-1H-Indole (BPR0L075) in human colorectal cancer cells |
- |
|
| [徐祖安] 期刊論文 |
2014-01-08 |
Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer |
- |
|
| [蔣維棠] 期刊論文 |
2012-06-07 |
3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) |
- |
|
| [李靜琪] 期刊論文 |
2012-09 |
Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors |
- |
|
| [羅履維] 期刊論文 |
2010-01 |
Enhanced photoacoustic stability of gold nanorods by silica matrix confinement |
- |
|
| [趙宇生(2002-2013)] 期刊論文 |
2012-02 |
Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents |
- |
|
| [趙宇生(2002-2013)] 期刊論文 |
2010-10-28 |
Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency |
- |
|
| [陳炯東] 期刊論文 |
2010-12 |
Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening |
- |
|
| [蔣維棠] 期刊論文 |
2011-07 |
Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) |
- |
|
| [徐祖安] 期刊論文 |
2012-01 |
BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML |
- |
|
| [夏克山] 期刊論文 |
2012-02 |
Discovery of novel stem cell mobilizers that target the CXCR4 receptor |
- |
|
| [羅履維] 期刊論文 |
2012-04-19 |
Visualizing dynamics of sub-hepatic distribution of nanoparticles using intravital multiphoton fluorescence microscopy |
- |
|
| [陳炯東] 期刊論文 |
2012-09 |
HDAC inhibitors augmented cell migration and metastasis through induction of PKCs leading to identification of low toxicity modalities for combination cancer therapy |
- |
|
| [陳炯東] 期刊論文 |
2013-05 |
H2O2 accumulation mediates differentiation capacity alteration, but not proliferative decline in senescent human fetal mesenchymal stem cells |
- |
|
| [謝興邦] 期刊論文 |
2013-05 |
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules |
- |
|
| [謝興邦] 期刊論文 |
2013-06-28 |
Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor |
- |
|
| [葉燈光] 期刊論文 |
2013-11 |
BPR0C305, an orally active microtubule-disrupting anticancer agent |
- |
|
| [陳炯東] 期刊論文 |
2014-04 |
Treatment of chemotherapy-induced neutropenia in a rat model by using multiple daily doses of oral administration of G-CSF-containing nanoparticles |
- |
|
| [羅履維] 期刊論文 |
2014-05-30 |
Enhanced plasmonic resonance energy transfer in mesoporous silica-encased gold nanorod for two-photon-activated photodynamic therapy |
- |
|
| [陳炯東] 期刊論文 |
2014-08-04 |
Effects of dipeptidyl peptidase-4 inhibition with MK-0431 on syngeneic mouse islet transplantation |
- |
|
| [劉柯俊] 期刊論文 |
2015-04 |
IL-1beta promotes malignant transformation and tumor aggressiveness in oral cancer |
- |
|
| [郭靜娟] 期刊論文 |
2015-08 |
Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway |
- |
|
| [羅履維] 期刊論文 |
2016-02 |
Dynamic in vivo SPECT imaging of neural stem cells functionalized with radiolabeled nanoparticles for tracking of glioblastoma |
- |
|
| [蕭金福] 期刊論文 |
2016-06 |
Assessing the consistency of the treatment effect under the discrete random effects model in multiregional clinical trials |
- |
|
| [蔡慧珍] 期刊論文 |
2016-10 |
BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia |
- |
|
| [謝興邦] 期刊論文 |
2016-12 |
Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation |
- |
|
| [郭書辰] 期刊論文 |
2018-06 |
Risk of mortality of Catheter-Related Bloodstream Infections caused by acinetobacter species: Is early removal of the catheters associated with a better survival outcome? |
- |
|
| [翁紹華] 期刊論文 |
2017-05 |
1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A novel opioid receptor agonist with less accompanying gastrointestinal dysfunction than morphine |
- |
|
| [羅履維] 期刊論文 |
2017-08 |
Lectin-functionalized mesoporous silica nanoparticles for endoscopic detection of premalignant colonic lesions |
- |
|
| [鄒倫] 期刊論文 |
2017-07 |
Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates |
- |
|
| [李秀珠] 期刊論文 |
2017-07 |
Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors |
- |
|
| [郭書辰] 期刊論文 |
2017-09 |
Multicenter study of the relationship between carbapenem MIC values and clinical outcome of patients with Acinetobacter Bacteremia |
- |
|
| [郭書辰] 期刊論文 |
2017-09 |
Multicenter study of clinical features of breakthrough acinetobacter bacteremia during carbapenem therapy |
- |
|
| [陳炯東] 期刊論文 |
2017-07-07 |
CCM111, the water extract of Antrodia cinnamomea, regulates immune-related activity through STAT3 and NF-kappaB pathways |
- |
|
| [郭書辰] 期刊論文 |
2018-10 |
Community-acquired bloodstream infections caused by Acinetobacter baumannii: A matched case-control study |
- |
|
| [陳炯東] 期刊論文 |
2018-04 |
Effects of female sex hormones on folic acid-induced anti-angiogenesis |
- |
|
| [夏克山] 期刊論文 |
2018-02-08 |
Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond |
- |
|
| [陳炯東] 期刊論文 |
2018-04 |
PSPC1 mediates TGF-beta1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis |
- |
|
| [陳炯東] 期刊論文 |
2018-07 |
An intestinal "Transformers"-like nanocarrier system for enhancing the oral bioavailability of poorly water-soluble drugs |
- |
|
| [陳炯東] 期刊論文 |
2019-01 |
CSC-3436 inhibits TWIST-induced epithelial-mesenchymal transition via the suppression of Twist/Bmi1/Akt pathway in head and neck squamous cell carcinoma |
- |
|
| [李靜琪] 期刊論文 |
2019-03 |
Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors |
- |
|
| [岳嶽] 期刊論文 |
2019-03 |
Mutagenesis of the dengue virus NS4A protein reveals a novel cytosolic N-terminal domain responsible for virus-induced cytopathic effects and intramolecular interactions within the N-terminus of NS4A |
- |
|
| [羅履維] 期刊論文 |
2019-11 |
A novel mouse model of sporadic colon cancer induced by combination of conditional Apc genes and chemical carcinogen in the absence of cre recombinase |
- |
|
| [伍素瑩] 期刊論文 |
2019-04-10 |
Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants |
- |
|
| [陳炯東] 期刊論文 |
2019-09 |
Effects of boschnaloside from Boschniakia rossica on dysglycemia and islet dysfunction in severely diabetic mice through modulating the action of glucagon-like peptide-1 |
- |
|
| [鄒倫] 期刊論文 |
2019-07-11 |
Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates |
- |
|
| [岳嶽] 期刊論文 |
2019-08-27 |
A dengue virus type 2 (DENV-2) NS4B-interacting host factor, SERP1, reduces DENV-2 production by suppressing viral RNA replication |
- |
|
| [岳嶽] 期刊論文 |
2019-12 |
A novel flavivirus entry inhibitor, BP34610, discovered through high-throughput screening with dengue reporter viruses |
- |
|
| [劉滄梧] 期刊論文 |
2020-02-18 |
Impacts of intralipid on nanodrug abraxane therapy and on the innate immune system |
- |
|
| [陳炯東] 期刊論文 |
2020-08 |
Artificial intelligence approach fighting COVID-19 with repurposing drugs |
- |
|
| [陳炯東] 期刊論文 |
2020-10 |
A bubble bursting-mediated oral drug delivery system that enables concurrent delivery of lipophilic and hydrophilic chemotherapeutics for treating pancreatic tumors in rats |
- |
|
| [李秀珠] 期刊論文 |
2020-08 |
Repurposing old drugs as antiviral agents for coronaviruses |
- |
|
| [徐祖安] 期刊論文 |
2020-08-20 |
Discovery of M protease inhibitors encoded by SARS-CoV-2 |
- |
|
| [蕭金福] 期刊論文 |
2021-01 |
Use of a two-sided tolerance interval in the design and evaluation of biosimilarity in clinical studies |
- |
|
| [陳炯東] 期刊論文 |
2020-11 |
Molecular profiling of afatinib-resistant non-small cell lung cancer cells in vivo derived from mice |
- |
|
| [紀雅惠] 期刊論文 |
2021-05-19 |
Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins |
- |
|
| [謝興邦] 期刊論文 |
2021-11-15 |
Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization |
- |
|
| [翁紹華] 期刊論文 |
2022-11 |
Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone |
- |
|
| [李秀珠] 期刊論文 |
2022-07-21 |
The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b |
- |
|
| [陳炯東] 期刊論文 |
2022-11-01 |
Peritoneal effluent MicroRNA profile for detection of encapsulating peritoneal sclerosis |
- |
|
| [陳炯東] 期刊論文 |
2022-10-13 |
Targeting the phosphatidylserine-immune checkpoint with a small-molecule maytansinoid conjugate |
- |
|
| [陳炯東] 期刊論文 |
2022-11-15 |
BPR0C261, an analogous of microtubule disrupting agent D-24851 enhances the radiosensitivity of human non-small cell lung cancer cells via p53-dependent and p53-independent pathways |
- |
|
| [劉士任] 期刊論文 |
2022-12-02 |
Omicron-specific mRNA vaccine induced cross-protective immunity against ancestral SARS-CoV-2 infection with low neutralizing antibodies |
- |
|
| [李秀珠] 期刊論文 |
2023-01-19 |
The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b [Erratum:Pharmaceutics. 2022 Jul 21;14(7):Article number 1511.] |
- |
|
| [李秀珠] 期刊論文 |
2023-07-20 |
Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin |
- |
|
| [吳其炘] 期刊論文 |
2024-01-25 |
Unlocking the secrets behind advanced artificial intelligence language models in deidentifying Chinese-English mixed clinical text: Development and validation study |
- |
|
| [紀雅惠] 期刊論文 |
2024-06-01 |
Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus |
- |
|
| [葉修華] 期刊論文 |
2024-07-17 |
Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia |
- |
|
| [葉修華] 期刊論文 |
2024-10-29 |
DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration |
- |
|
| [蕭子凱(2001-2004)] 會議論文/會議摘要 |
2003-10 |
A new approach for pulse processing in PET |
- |
|
| [其他] 會議論文/會議摘要 |
2004-10 |
A preliminary experimental valiadation of a new approach for pulse processing in PET |
- |
|
| [其他] 會議論文/會議摘要 |
2004 |
Modular detector systems for nuclear medicine imaging |
- |
|
| [其他] 會議論文/會議摘要 |
2006-03 |
A novel model of the geometric and detector response for limited angular sampling pinhole SPECT |
- |
|
| [林名釗] 會議論文/會議摘要 |
2005-10 |
A row-action image reconstruction of short time frame for microPET dynamic study |
- |
|
| [林名釗] 會議論文/會議摘要 |
2007-11 |
A unified segmentation method for CT image segmentation with contrast agent |
- |
|
| [其他] 會議論文/會議摘要 |
2007-10 |
Least-square pinhole SPECT calibration using a forward projector modeling misalignment |
- |
|
| [陳炯東] 期刊論文 |
2008-11-28 |
Anti-angiogenic action of 5,5-diphenyl-2-thiohydantoin-N10 (DPTH-N10) |
- |
|
| [羅履維] 期刊論文 |
2009-01-23 |
Near-infrared mesoporous silica nanoparticles for optical imaging: Characterization and in vivo biodistribution |
- |
|
| [羅秀容] 期刊論文 |
2009-03 |
Non-lethal Candida albicans cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by lethal wild-type cells |
- |
|
| [陳炯東] 期刊論文 |
2009-04 |
In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery |
- |
|
| [蔣維棠] 期刊論文 |
2009-04-01 |
Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors |
- |
|
| [蔣維棠] 期刊論文 |
2009-03-15 |
Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors |
- |
|
| [張文祥] 期刊論文 |
2009-04 |
ALA-PDT results in phenotypic changes and decreased cellular invasion in surviving cancer cells |
- |
|
| [葉燈光] 期刊論文 |
2009-07 |
Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes |
- |
|
| [伍素瑩] 期刊論文 |
2009-07-23 |
Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity |
- |
|
| [謝興邦] 期刊論文 |
2009-08-13 |
Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach |
- |
|
| [林名釗] 期刊論文 |
2010-04 |
Detection of experimentally induced pulmonary granuloma Inflammation in monocyte chemoattractant protein-1 reporter mice |
- |
|
| [蔡世峯] 期刊論文 |
2009-10-09 |
KEAP1 E3 Ligase-Mediated Downregulation of NF-kappaB Signaling by Targeting IKKbeta |
- |
|
| [林名釗] 期刊論文 |
2009-10 |
Noninvasive optical imaging for tracking gene delivery and recombination in tumor |
- |
|
| [陳炯東] 期刊論文 |
2010-09 |
Intravenous paclitaxel against metastasis of human gastric tumors of diffuse type |
- |
|
| [陳炯東] 期刊論文 |
2010-02 |
Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91 |
- |
|
| [陳炯東] 期刊論文 |
2010-02 |
Abnormal expressions of circadian-clock and circadian clock-controlled genes in the livers and kidneys of long-term, high-fat-diet-treated mice |
- |
|
| [何英剛(2006-2011)] 期刊論文 |
2010-03 |
Sex differences in high-fat diet-induced obesity, metabolic alterations and learning, and synaptic plasticity deficits in mice |
- |
|
| [陳炯東] 期刊論文 |
2010-03 |
Synthesis and biological activities of 2-Amino-1-arylidenamino imidazoles as orally active anticancer agents |
- |
|
| [羅履維] 期刊論文 |
2010-07 |
Surface charge-mediated rapid hepatobiliary excretion of mesoporous silica nanoparticles |
- |
|
| [陳新(2002-2015)] 期刊論文 |
2010-06-15 |
(2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV |
- |
|
| [陳炯東] 期刊論文 |
2010-11 |
Self-assembled pH-sensitive nanoparticles: A platform for oral delivery of protein drugs |
- |
|
| [陳炯東] 期刊論文 |
2011-01 |
BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities |
- |
|
| [趙宇生(2002-2013)] 期刊論文 |
2011-01-13 |
Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes |
- |
|
| [羅秀容] 期刊論文 |
2012-03 |
R432 is a key residue for the multiple functions of Ndt80p in Candida albicans |
- |
|
| [夏興國] 期刊論文 |
2013-02 |
Targeted endostatin-cytosine deaminase fusion gene therapy plus 5-fluorocytosine suppresses ovarian tumor growth |
- |
|
| [陳炯東] 期刊論文 |
2012-09 |
Elucidating the signaling mechanism of an epithelial tight-junction opening induced by chitosan |
- |
|
| [陳炯東] 期刊論文 |
2012-09 |
Putative tumor metastasis-associated genes in human gastric cancer |
- |
|
| [林名釗] 期刊論文 |
2012-08 |
Ferritin-red fluorescent protein fusion reporter for magnetic resonance and optical imaging |
- |
|
| [陳炯東] 期刊論文 |
2013-01-23 |
In vivo imaging of brain infarct with the novel fluorescent probe psvue 794 in a rat middle cerebral artery occlusion-reperfusion model |
- |
|
| [鄒小蕙] 期刊論文 |
2013-11 |
A 12-Year ecological study of hip fracture rates among older Taiwanese adults |
- |
|
| [陳炯東] 期刊論文 |
2013-06 |
Candida albicans ENO1 null mutants exhibit altered drug susceptibility, hyphal formation, and virulence |
- |
|
| [郭靜娟] 期刊論文 |
2017-12 |
Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells |
- |
|
| [李靜琪] 期刊論文 |
2018-01-01 |
Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2 |
- |
|
| [羅履維] 會議論文/會議摘要 |
2016-10-29 |
Rapid measurement of fluorescence lifetimes using SIPM detection and waveform sampling |
- |
|
| [陳立宗] 期刊論文 |
2018-08-24 |
BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor |
- |
|
| [陳炯東] 期刊論文 |
2019-01 |
CCM111 prevents hepatic fibrosis via cooperative inhibition of TGF-Beta Wnt and STAT3 signaling pathways |
- |
|
| [陳炯東] 期刊論文 |
2019-06-15 |
Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems |
- |
|
| [陳炯東] 期刊論文 |
2019-03-28 |
Phase-changeable nanoemulsions for oral delivery of a therapeutic peptide: Toward targeting the pancreas for antidiabetic treatments using lymphatic transport |
- |
|
| [陳志豪] 期刊論文 |
2019-04-01 |
A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus |
- |
|
| [翁紹華] 期刊論文 |
2019-04-01 |
The in vivo antinociceptive and mu-opioid receptor activating effects of the combination of N-phenyl-2′,4′-dimethyl-4,5′-bi-1,3-thiazol-2-amines and naloxone |
- |
|
| [羅履維] 期刊論文 |
2020-05-20 |
Annealing-modulated nanoscintillators for nonconventional X-ray activation of comprehensive photodynamic effects in deep cancer theranostics |
- |
|
| [蕭金福] 期刊論文 |
2020-10 |
Operational experiences in China and statistical issues on the conduct of clinical trials during the COVID-19 pandemic |
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| [陳炯東] 期刊論文 |
2020-10-08 |
Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery |
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| [鄒倫] 期刊論文 |
2021-01 |
BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy |
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| [蔣維棠] 期刊論文 |
2021-01 |
Potent and orally active purine-based fetal hemoglobin inducers for treating Beta-thalassemia and sickle cell disease |
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| [陳主智] 期刊論文 |
2021-03 |
Projection of future temperature extremes, related mortality, and adaptation due to climate and population changes in Taiwan |
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| [陳炯東] 期刊論文 |
2021-08-01 |
DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity |
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| [李秀珠] 期刊論文 |
2021-08-13 |
Remdesivir and cyclosporine synergistically inhibit the human coronaviruses OC43 and SARS-CoV-2 |
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| [鄒倫] 期刊論文 |
2022-02-15 |
Click chemistry and multicomponent reaction for linker diversification of zinc dipicolylamine-based drug conjugates |
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| [張俊彥] 期刊論文 |
2022-03-02 |
Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy |
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| [陳炯東] 期刊論文 |
2021-12 |
Implanted islet mass influences the effects of dipeptidyl peptidase-IV inhibitor LAF237 on transplantation outcomes in diabetic mice |
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| [羅履維] 期刊論文 |
2022-07-13 |
Multimodal magnetic resonance and photoacoustic imaging of tumor-specific enzyme-responsive hybrid nanoparticles for oxygen modulation |
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| [翁紹華] 期刊論文 |
2022-12-05 |
Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation |
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| [謝興邦] 期刊論文 |
2023-02-07 |
Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer |
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| [其他] 期刊論文 |
2023-09 |
Nucleus accumbens deep brain stimulation improves depressive-like behaviors through BDNF-mediated alterations in brain functional connectivity of dopaminergic pathway |
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| [吳嘉文] 期刊論文 |
2023-09-07 |
Controlled encapsulation of gold nanoparticles into Zr-metal-organic frameworks with improved detection limitation of volatile organic compounds via surface-enhanced raman scattering |
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| [陳炯東] 期刊論文 |
2024-02-16 |
Postfermented tea extract potently alleviates glucose metabolism disorders in vitro and in vivo |
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| [陳炯東] 期刊論文 |
2013-01 |
Effects of pH on molecular mechanisms of chitosan–integrin interactions and resulting tight-junction disruptions |
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| [陳炯東] 期刊論文 |
2013-10 |
Combination therapy via oral co-administration of insulin- and exendin-4-loaded nanoparticles to treat type 2 diabetic rats undergoing OGTT |
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| [陳炯東] 期刊論文 |
2015-09 |
Self-assembling bubble carriers for oral protein delivery |
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| [陳炯東] 期刊論文 |
2013-10 |
Noninvasive imaging oral absorption of insulin delivered by nanoparticles and its stimulated glucose utilization in controlling postprandial hyperglycemia during OGTT in diabetic rats |
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| [蔣維棠] 期刊論文 |
2015-07 |
Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations |
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| [蔣維棠] 期刊論文 |
2013-06 |
Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) |
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| [李靜琪] 期刊論文 |
2016-05 |
N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors |
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| [陳炯東] 會議論文/會議摘要 |
2016-02 |
Multifunctional nanoparticles for oral protein drug delivery |
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| [羅履維] 期刊論文 |
2013-12 |
Nanoparticle-programmed self-destructive neural stem cells for glioblastoma targeting and therapy |
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