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分子與基因醫學研究所
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Items for Author "Shan, YS"
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Showing 123 items.
Collection
Date
Title
Relation
Bitstream
[姜乃榕] 會議論文/會議摘要
2022-10
An integrated microfluidic device for automated detection of cancer cells from bile for cholangiocarcinoma prognosis
-
[陳立宗] 會議論文/會議摘要
2022-02-01
A prospective phase II study of biweekly S-1, leucovorin and gemcitabine in elderly patients with locally advanced or metastatic pancreatic adenocarcinoma
-
[姜乃榕] 會議論文/會議摘要
2021-05
TCOG T5217 trial: A phase II randomized study of SLOG versus modified FOLFIRINOX as the first-line treatment in locally advanced or metastatic pancreatic ductal adenocarcinoma
-
[姜乃榕] 會議論文/會議摘要
2019-02
Mutational landscape by targeted next-generation sequencing in EBV-associated lymphoepithelioma-like cholangiocarcinoma
-
[陳立宗] 會議論文/會議摘要
2017-11
Subgroup analysis by prior non-liposomal irinotecan therapy in NAPOLI-1: A phase 3 study of nal-IRI65-fluorouracil/leucovorin in patients with metastatic pancreatic ductal adenocarcinoma previously treated with gemcitabine-based therapy
-
[陳立宗] 會議論文/會議摘要
2017-11
CA19-9 decrease and overall survival (OS) in the NAPOLI-1 trial of liposomal irinotecan (nal-IRI) � 5-fluorouracil and leucovorin (5-FU/LV) in metastatic pancreatic ductal adenocarcinoma (mPDAC) previously treated with gemcitabine-based therapy
-
[姜乃榕] 會議論文/會議摘要
2017-02
A phase II trial of modified gemcitabine plus S-1 combination as the first-line treatment in patients with advanced biliary tract cancer
-
[陳立宗] 會議論文/會議摘要
2016-12
Efficacy and safety of nanoliposomal irinotecan (nal-IRI, MM-398, PEP02, BAX-2398) in patients with metastatic pancreatic cancer in Asia: A subgroup analysis of the phase 3 NAPOLI-1 Study
-
[陳立宗] 會議論文/會議摘要
2016-10
Final results of NAPOLI-1: A phase 3 study of nal-IRI (MM-398) +/- 5-fluorouracil and leucovorin (5-FU/LV) vs 5-FU/LV in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based therapy
-
[陳立宗] 會議論文/會議摘要
2016-05
Updated overall survival (OS) analysis of NAPOLI-1: Phase 3 study of nanoliposomal irinotecan (nal-IRI, MM-398), with or without 5-fluorouracil and leucovorin (5-FU/LV), vs 5-FU/LV in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine
-
[陳立宗] 會議論文/會議摘要
2015-01
Expanded analyses of napoli-1: Phase 3 study of MM-398 (nal-IRI), with or without 5-fluorouracil and leucovorin, versus 5-fluorouracil and leucovorin, in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based therapy
-
[陳立宗] 會議論文/會議摘要
2014-01
Impact of ROS1, ALK, and/or MET expression level on the therapeutic efficacy of GEMOX with and without cetuximab in ABTC: A post hoc analysis of a randomized phase II trial
-
[陳立宗] 會議論文/會議摘要
2013-05
KRAS mutation status-stratified randomized phase II trial of GEMOX with and without cetuximab in advanced biliary tract cancer (ABTC): The TCOG T1210 trial
-
[蕭金福] 會議論文/會議摘要
2015-05
A phase II study of sequential capecitabine plus oxaliplatin (XELOX) followed by docetaxel plus capecitabine (TX) in patients with unresectable gastric adenocarcinoma: The TCOG T3211 trial
-
[陳立宗] 會議論文/會議摘要
2015-09
The safety and efficacy of everolimus for the treatment of progressive gastroenteropancreatic neuroendocrine tumors: A multi-institution observational study in Taiwan
-
[蕭金福] 會議論文/會議摘要
2015-12
A phase II study of sequential capecitabine plus oxaliplatin (XELOX) followed by docetaxel plus capecitabine (TX) in patients with unresectable gastric adenocarcinoma-TCOG 3211 clinical trial
-
[陳立宗] 會議論文/會議摘要
2016-02
Expanded analyses of NAPOLI-1: Phase 3 study of nal-IRI (MM-398), with or without 5-fluorouracil (5FU) and leucovorin (LV), versus 5-fluorouracil and leucovorin (5FU/LV), in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based therapy
-
[張書銘] 會議論文/會議摘要
2015-08
The association between periodontal disease and pancreatic cancer
-
[姜乃榕] 會議論文/會議摘要
2016-02
Results of Phase II trial of AUY922, a novel heat shock protein inhibitor in patients with metastatic gastrointestinal stromal tumor (GIST) and imatinib and sunitinib therapy
-
[姜乃榕] 會議論文/會議摘要
2016-02
Phase I trial of biweekly S-1, leucovorin, oxaliplatin, and gemcitabine (the SLOG regimen) in metastatic pancreatic adenocarcinoma (mPDAC)
-
[陳立宗] 會議論文/會議摘要
2016-02
Phase III study of nanoliposomal irinotecan (nal-IRI, MM-398), with or without 5-fluorouracil and leucovorin (5-FU/LV), versus 5-FU/LV in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based therapy
-
[洪文俊] 會議論文/會議摘要
2016-11
Role of epigenetic regulator EHMT2 in the regulation of gemcitabine resistance in pancreatic cancer
-
[陳立宗] 會議論文/會議摘要
2016-10
Time course of selected treatment emergent adverse events (TEAEs) in NAPOLI-1: A phase 3 study of nal-IRI (MM-398) +/- 5-fluorouracil and leucovorin (5-FU/LV) vs 5-FU/LV in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based ther
-
[陳立宗] 會議論文/會議摘要
2016-12
Sequential use of everolimus and sunitinib in treating WHO grade 1 and 2 pancreatic neuroendocrine tumors-retrospective multi-center study in Taiwan
-
[陳立宗] 會議論文/會議摘要
2017-06-26
CA19-9 decrease and overall survival (OS) in the NAPOLI-1 trial of liposomal irinotecan (nal-IRI) +/- 5-fluorouracil and leucovorin (5FU/LV) in metastatic pancreatic ductal adenocarcinoma (mPDAC) previously treated with gemcitabine-based therapy
-
[陳立宗] 會議論文/會議摘要
2017-06-26
Subgroup analysis by prior non-liposomal irinotecan therapy in NAPOLI-1: A phase 3 study of nal-IRI +/- 5-fluorouracil/leucovorin in patients with metastatic pancreatic ductal adenocarcinoma previously treated with gemcitabine-based therapy
-
[陳立宗] 會議論文/會議摘要
2017-09
Mutant KIT translocates into the nucleus and induces NFKBIB expression that leads to KIT expression in imatinib-resistant gastrointestinal stromal tumors
-
[蔡慧珍] 會議論文/會議摘要
2018-01
The role of aberrant mitochondrial phosphoenolpyruvate carboxykinase expression in pancreatic neuroendocrine tumors
-
[張書銘] 會議論文/會議摘要
2018-01
Environmental tobacco smoke and risk of pancreatic cancer among never smokers
-
[洪文俊] 會議論文/會議摘要
2018-12
c-Myc promotes lymphatic metastasis of pancreatic neuroendocrine tumor through VEGFC upregulation
-
[張書銘] 會議論文/會議摘要
2018-12
The epidemiology of gastric cancer in the era of H. pylori eradication: A nation-wide registry-based study in Taiwan
-
[鄒小蕙] 會議論文/會議摘要
2018-11
TCOG T1308 study: The final results of a phase II trial of modified gemcitabine plus S-1 combination as the first-line treatment in patients with advanced biliary tract cancer
-
[常慧如] 會議論文/會議摘要
2018-10
Randomized, phase III trial comparing adjuvant gemcitabine (Gem) versus Gem plus chemoradiation (CCRT) in curatively resected pancreatic ductal adenocarcinoma (PDAC): A Taiwan cooperative oncology group study
-
[姜乃榕] 會議論文/會議摘要
2018-10
Multicenter, phase II trial of biweekly S-1, leucovorin (LV), oxaliplatin and gemcitabine (SLOG) in metastatic pancreatic adenocarcinoma (mPDAC): Final report of TCOG T1211 study
-
[洪文俊] 期刊論文
2019-07
Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer
-
[陳立宗] 期刊論文
2019-09
Pancreatic stellate cells activated by mutant KRAS-mediated PAI-1 upregulation foster pancreatic cancer progression via IL-8
-
[其他] 期刊論文
2020-01
DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination
-
[蔡坤志] 期刊論文
2021-05
A multi-mode Wnt- and stemness-regulatory module dictated by FOXM1 and ASPM isoform I in gastric cancer[Erratum:Gastric Cancer. 2021 May;24(3):624-639.]
-
[姜乃榕] 會議論文/會議摘要
2021-09
A phase II trial of nivolumab and gemcitabine and S-1 as the first-line treatment in patients with advanced biliary tract cancer
-
[姜乃榕] 會議論文/會議摘要
2020-11
An integrated microfluidic platform for cholangiocarcinoma diagnosis from clinical bile juice samples by utilizing multiple affinity reagents
-
[陳立宗] 期刊論文
2022-02-24
Semaphorin 6C suppresses proliferation of pancreatic cancer cells via inhibition of the AKT/GSK3/beta-catenin/cyclin D1 pathway
-
[姜乃榕] 期刊論文
2022-06-16
Cancer-cell-derived cell-free DNA can predict distant metastasis earlier in pancreatic cancer: A prospective cohort study
-
[姜乃榕] 期刊論文
2022-10
The immune microenvironment features and response to immunotherapy in EBV-associated lymphoepithelioma-like cholangiocarcinoma
-
[陳立宗] 期刊論文
2022-06-22
Dosing pattern and early cumulative dose of liposomal irinotecan in metastatic pancreatic cancer: A real-world multicenter study
-
[姜乃榕] 期刊論文
2022-06-26
The differential clinical impacts of cachexia and sarcopenia on the prognosis of advanced pancreatic cancer
-
[陳立宗] 會議論文/會議摘要
2022-07
A phase II trial of nivolumab, gemcitabine and S-1 as the frst-line treatment in patients with biliary tract cancer
-
[陳立宗] 會議論文/會議摘要
2022-07
Improved survival with neoadjuvant chemotherapy in stage III pancreatic cancer: A single institutional experience
-
[姜乃榕] 期刊論文
2022-09-15
Predictive value of albumin combined with neutrophil-to-lymphocyte ratio for efficacy and safety profiles in patients with pancreatic ductal adenocarcinoma receiving liposomal irinotecan plus 5-fluorouracil and leucovorin
-
[姜乃榕] 會議論文/會議摘要
2022-06
Comparative genomic analysis and its prognostic impact on survival between viral hepatitis-related and non-viral hepatitis intrahepatic cholangiocarcinoma
-
[姜乃榕] 期刊論文
2022-12-15
An integrated microfluidic system for cholangiocarcinoma diagnosis from bile by using specific affinity probes
-
[蔡慧珍] 期刊論文
2022-11-06
PTEN regulates invasiveness in pancreatic neuroendocrine tumors through DUSP19-mediated VEGFR3 dephosphorylation
-
[陳立宗] 期刊論文
2023-08
The impact of preoperative waiting time in Stage II-III gastric or gastroesophageal junction cancer: A population-based cohort study
-
[姜乃榕] 會議論文/會議摘要
2023-06
Phase 1 studies of D07001-F4 and D07001-softgel capsule: Oral metronomic gemcitabine in subjects with advanced solid tumors
-
[蘇勇曄] 會議論文/會議摘要
2023-11
Single-cell RNA sequencing via Endoscopic Ultrasoundguided Fine-Needle Biopsy (EUS-FNB) Pancreatic Biopsies uncovered an aggressive subclone with a poor prognosis
-
[陳立宗] 期刊論文
2024-02-13
Germline mutations of homologous recombination genes and clinical outcomes in pancreatic cancer: A multicenter study in Taiwan
-
[陳立宗] 期刊論文
2024-10
A phase 1 study of biweekly nab-paclitaxel/oxaliplatin/S-1/LV for advanced upper gastrointestinal cancers: TCOG T1216 study
-
[蔡慧珍] 期刊論文
2024-07-11
Survival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: A nationwide registry study
-
[陳立宗] 期刊論文
2013-06-20
Selecting tyrosine kinase inhibitors for gastrointestinal stromal tumor with secondary KIT activation-loop domain mutations
-
[陳立宗] 期刊論文
2011-12
Induction chemotherapy with gemcitabine, oxaliplatin, and 5-Fluorouracil/Leucovorin followed by concomitant chemoradiotherapy in patients with locally advanced pancreatic cancer: A Taiwan cooperative oncology group phase II study
-
[蔡坤志] 期刊論文
2013-11
A gene expression signature of epithelial tubulogenesis and a role for ASPM in pancreatic tumor progression
-
[陳立宗] 期刊論文
2015-05
A KRAS mutation status-stratified randomized phase II trial of gemcitabine and oxaliplatin alone or in combination with cetuximab in advanced biliary tract cancer
-
[張書銘] 期刊論文
2015-06
Comprehensive analysis of the incidence and survival patterns of lung cancer by histologies, including rare subtypes, in the era of molecular medicine and targeted therapy: A nation-wide cancer registry-based study from Taiwan
-
[陳立宗] 期刊論文
2015-10
Epigenetic regulation in the carcinogenesis of cholangiocarcinoma
-
[陳立宗] 期刊論文
2016-01
Investigating the association between periodontal disease and risk of pancreatic cancer
-
[陳立宗] 期刊論文
2016-02
Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): A global, randomised, open-label, phase 3 trial
-
[蕭金福] 期刊論文
2016-01
A phase II study of sequential capecitabine plus oxaliplatin followed by docetaxel plus capecitabine in patients with unresectable gastric adenocarcinoma: The TCOG 3211 clinical trial
-
[其他] 期刊論文
2016-07
KIT exon 11 codons 557-558 deletion mutation promotes liver metastasis through the CXCL12/CXCR4 axis in gastrointestinal stromal tumors
-
[陳立宗] 期刊論文
2016-07
Development of nanoliposomal irinotecan (nal-IRI, MM-398, PEP02) in the management of metastatic pancreatic cancer
-
[陳立宗] 期刊論文
2016-12
The efficacy and safety of everolimus for the treatment of progressive gastroenteropancreatic neuroendocrine tumors: A multi-institution observational study in Taiwan
-
[洪文俊] 期刊論文
2016-09
The histone methyltransferase G9a as a therapeutic target to override gemcitabine resistance in pancreatic cancer
-
[蔡坤志] 期刊論文
2016-12
Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells
-
[姜乃榕] 期刊論文
2017-06-26
A microfluidic chip for detecting cholangiocarcinoma cells in human bile
-
[蔡慧珍] 期刊論文
2018-11
The incidence and survival of pancreatic cancer by histology, including rare subtypes: A nation-wide cancer registry-based study from Taiwan
-
[陳立宗] 期刊論文
2018-11-07
Survival with nal-IRI (liposomal irinotecan) plus 5-fluorouracil and leucovorin versus 5-fluorouracil and leucovorin in per-protocol and non-per-protocol populations of NAPOLI-1: Expanded analysis of a global phase 3 trial
-
[洪文俊] 期刊論文
2018-12-20
Protein arginine methyltransferase 3 enhances chemoresistance in pancreatic cancer by methylating hnRNPA1 to increase ABCG2 expression
-
[陳立宗] 期刊論文
2019-05-20
Loss of the transcriptional repressor TGIF1 results in enhanced Kras-driven development of pancreatic cancer
-
[陳立宗] 期刊論文
2019-10
The epidemiology of gastric cancers in the era of Helicobacter pylori eradication: A nation-wide cancer registry-based study in Taiwan
-
[陳立宗] 期刊論文
2019-09
Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors
-
[蔡坤志] 期刊論文
2019-12
The differential distributions of ASPM isoforms and their roles in Wnt signaling, cell cycle progression, and pancreatic cancer prognosis
-
[陳立宗] 期刊論文
2020-02
Liposomal irinotecan in metastatic pancreatic adenocarcinoma in Asian patients: Subgroup analysis of the NAPOLI-1 study
-
[蕭金福] 期刊論文
2020-05
An open-label, single-arm, two-stage, multicenter, phase II study to evaluate the efficacy of TLC388 and genomic analysis for poorly differentiated neuroendocrine carcinomas
-
[張書銘] 期刊論文
2020-05-26
Validation of genome-wide association study-identified single nucleotide polymorphisms in a case-control study of pancreatic cancer from Taiwan
-
[陳立宗] 期刊論文
2020-10
Multicentre, phase II study of gemcitabine and S-1 in patients with advanced biliary tract cancer: TG1308 study
-
[蔡慧珍] 期刊論文
2021-01
c-Myc promotes lymphatic metastasis of pancreatic neuroendocrine tumor through VEGFC upregulation
-
[楊奕馨] 期刊論文
2021-11-30
Survival outcomes of management in metastatic gastric adenocarcinoma patients
-
[陳立宗] 期刊論文
2021-11-12
The prognostic and predictive role of chromogranin a in gastroenteropancreatic neuroendocrine tumors - A single-center experience
-
[姜乃榕] 期刊論文
2022-06
Effect of previous conventional irinotecan treatment in patients with pancreatic cancer being treated with liposomal irinotecan plus 5-fluorouracil and leucovorin
-
[姜乃榕] 期刊論文
2022-04-15
The impact of spleen volume on the survival of metastatic pancreatic adenocarcinoma patients receiving nanoliposomal irinotecan
-
[陳立宗] 期刊論文
2022-05-15
Improved survival with induction chemotherapy and conversion surgery in locally advanced unresectable pancreatic cancer: A single institution experience
-
[陳立宗] 期刊論文
2022-10
Impaired chromatin remodeling predicts better survival to modified gemcitabine and S-1 plus nivolumab in advanced biliary tract Cancer: A phase II T1219 study
-
[其他] 期刊論文
2022-08-19
Phosphomimetic Dicer S1016E triggers a switch to glutamine metabolism in gemcitabine-resistant pancreatic cancer
-
[蘇勇曄] 期刊論文
2022-11-15
The impact of starting dose with or without subsequent dose escalation of liposomal irinotecan on treatment outcomes in patients with metastatic pancreatic ductal adenocarcinoma
-
[陳立宗] 期刊論文
2023-02-05
Real-world data validation of NAPOLI-1 nomogram for the prediction of overall survival in metastatic pancreatic cancer
-
[陳立宗] 期刊論文
2023-09-01
The experience of neoadjuvant chemotherapy versus upfront surgery in resectable pancreatic cancer. a cross sectional study
-
[陳立宗] 期刊論文
2023-08-15
Pancreatic cancer cell-derived semaphorin 3A promotes neuron recruitment to accelerate tumor growth and dissemination
-
[蔡坤志] 期刊論文
2012-08
Krüppel-like factor 10 expression as a prognostic indicator for pancreatic adenocarcinoma
-
[陳立宗] 期刊論文
2013-08
A multinational phase 2 study of nanoliposomal irinotecan sucrosofate (PEP02, MM-398) for patients with gemcitabine-refractory metastatic pancreatic cancer
-
[陳立宗] 期刊論文
2016-05-03
Expression levels of ROS1/ALK/c-MET and therapeutic efficacy of cetuximab plus chemotherapy in advanced biliary tract cancer
-
[姜乃榕] 期刊論文
2017-07-01
Automated selection of aptamers against cholangiocarcinoma cells on an integrated microfluidic platform
-
[姜乃榕] 期刊論文
2017-09
Screening of peptide specific to cholangiocarcinoma cancer cells using an integrated microfluidic system and phage display technology
-
[陳立宗] 期刊論文
2017-09-16
The regulatory role of aberrant Phosphatase and Tensin Homologue and Liver Kinase B1 on AKT/mTOR/c-Myc axis in pancreatic neuroendocrine tumors
-
[陳立宗] 期刊論文
2017-10-09
Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) regulates the cell metabolism of pancreatic neuroendocrine tumors (pNET) and de-sensitizes pNET to mTOR inhibitors
-
[蕭金福] 期刊論文
2018-07
The clinical impact of the novel tumor marker DR-70 in unresectable gastric cancer patients
-
[洪文俊] 期刊論文
2019-01
Beta-catenin-activated autocrine PDGF/Src signaling is a therapeutic target in pancreatic cancer
-
[陳立宗] 期刊論文
2020-01
A multicenter, phase I/II trial of biweekly S-1, leucovorin, oxaliplatin and gemcitabine in metastatic pancreatic adenocarcinoma–TCOG T1211 study
-
[姜乃榕] 期刊論文
2020-05
Exploring Circulating Tumor Cells in cholangiocarcinoma using a novel glycosaminoglycan probe on a microfluidic platform
-
[陳立宗] 期刊論文
2020-05-04
The impact of liposomal irinotecan on the treatment of advanced pancreatic adenocarcinoma: Real-world experience in a Taiwanese cohort
-
[姜乃榕] 期刊論文
2020-11-01
Aptamer probed isolation of circulating tumor cells in cholangiocarcinoma patients
-
[陳立宗] 期刊論文
2020-11-13
The impact of liposomal irinotecan on the treatment of advanced pancreatic adenocarcinoma: Real-world experience in a Taiwanese cohort [Erraturm: Scientific Reports. 2020 May 4;10:Article number 7420.]
-
[陳立宗] 期刊論文
2021-01-13
Development of possible next line of systemic therapies for gemcitabine-resistant biliary tract cancers: A perspective from clinical trials
-
[蔡坤志] 期刊論文
2021-05
A multi-mode Wnt- and stemness-regulatory module dictated by FOXM1 and ASPM isoform I in gastric cancer
-
[蕭金福] 期刊論文
2021-05
High expression of krüppel-like factor 10 or Smad4 predicts clinical benefit of adjuvant chemoradiotherapy in curatively resected pancreatic adenocarcinoma: From a randomized phase III trial
-
[蔡慧珍] 期刊論文
2021-04-12
An updated analysis of the epidemiologic trends of neuroendocrine tumors in Taiwan
-
[張書銘] 期刊論文
2021-07-15
No association between alcohol consumption and pancreatic cancer even among individuals genetically susceptible to the carcinogenicity of alcohol
-
[姜乃榕] 期刊論文
2021-11-01
Exfoliated tumor cells in bile as a promising indicator of disease status in cholangiocarcinoma
-
[蘇勇曄] 期刊論文
2021-11-20
Liposomal irinotecan pre-emptive dose reduction in patients with pancreatic ductal adenocarcinoma: 667 patients’ experience within a population-based study
-
[陳立宗] 期刊論文
2022-04
A phase II randomised trial of induction chemotherapy followed by concurrent chemoradiotherapy in locally advanced pancreatic cancer: the Taiwan Cooperative Oncology Group T2212 study
-
[姜乃榕] 期刊論文
2022-09
A prospective phase II study of biweekly S-1, leucovorin, and gemcitabine in elderly patients with locally advanced or metastatic pancreatic adenocarcinoma – The Taiwan Cooperative Oncology Group T1217 study
-
[陳立宗] 期刊論文
2023-02
The association between UGT1A1 polymorphisms and treatment toxicities of liposomal irinotecan
-
[邱燕楓] 期刊論文
2023-09
Carbohydrate antigen 19-9 response to initial adjuvant chemotherapy predicts survival and failure pattern of resected pancreatic adenocarcinoma but not which patients are suited for additional adjuvant chemoradiation therapy: From a prospective randomized study
-
[陳立宗] 期刊論文
2024-05
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