國家衛生研究院 NHRI:Item 3990099045/10051
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    题名: Following changes in the axillary secretions of two patients before and after bromhidrosis surgery using liquid chromatography-mass spectrometry
    作者: Ho, WT;Lee, LJ;Pan, JY
    贡献者: National Institute of Environmental Health Sciences
    摘要: Bromhidrosis negatively affects quality of life, and many patients undergo surgery for treatment. Complete apocrine gland removal markedly reduces body malodor; however, few studies have objectively evaluated changes in apocrine secretions and the degrees of improvement after surgery. We aimed to evaluate these physiological changes in patients who were satisfied after surgery. Apocrine gland secretions contain many odorous fatty acids, including linear-saturated, linear-unsaturated, and branched-unsaturated C6-C11 acids. 1,2 Here, we measured (E)-3-methyl-2-hexenoic acid (3M2H), 3-methyl-3-hydroxyhexanoic acid (HMHA), and 3-methyl-3-sulfanylhexan-1-ol (3M3SH) using liquid chromatography–mass spectrometry (LC–MS/MS). Especially, the 3M2H, a C7 branched unsaturated fatty acid is found in human apocrine gland secretions that has a particularly strong stench, especially in Caucasians and Asians.
    日期: 2017-03
    關聯: Dermatologic Surgery. 2017 Mar;43(3):459-462.
    Link to: http://dx.doi.org/10.1097/dss.0000000000000934
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1076-0512&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000398047200024
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85015201528
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