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| 題名: | Circulating 25-hydroxyvitamin D and physical performance in older adults: A nationwide study in Taiwan |
| 作者: | Chuang, SC;Chen, HL;Tseng, WT;Wu, IC;Hsu, CC;Chang, HY;Chen, YI;Lee, MM;Liu, K;Hsiung, CA |
| 貢獻者: | Division of Biostatistics and Bioinformatics;Division of Health Services and Preventive Medicine;Division of Geriatric Research;Division of Health Policy Translation |
| 摘要: | BACKGROUND: A previous study indicated that 31% of the elderly in Taiwan have a vitamin D deficiency. Vitamin D adequacy has been associated with physical performance in the elderly. OBJECTIVES: The first aim of the current study was to identify the determinants for vitamin D deficiency. The second aim was to evaluate the association between vitamin D status and physical performance. DESIGN: A total of 5664 community-dwelling participants aged >/=55 y were recruited since 2008. Plasma total 25-hydroxyvitamin D concentrations were originally determined by ELISA and calibrated to a chemiluminescence measurement. Physical performance was assessed by handgrip strength, the Short Physical Performance Battery, timed up and go, a 6-min walk test, and single-leg stands. Multiple linear regression and logistic regression were used to estimate the cross-sectional associations. RESULTS: Vitamin D inadequacy (<50 nmol/L) was related to higher education (P-trend < 0.01), body mass index [(BMI; in kg/m2) ORs (95% CIs) for >/=30 compared with 18.5 to <25 were 1.78 (1.14, 2.78) for men and 1.53 (1.11, 2.11) for women], and vegetable intake [fourth compared with first quartile, 1.58 (1.15, 2.18) for men and 2.38 (1.82, 3.12) for women]. Higher intakes of fish [fourth compared with first quartile, 0.44 (0.33, 0.59) for men and 0.27 (0.21, 0.36) for women] and milk [fourth compared with first quartile, 0.46 (0.31, 0.69) for men and 0.69 (0.49, 0.95) for women] were associated with lower risk of vitamin D inadequacy. Few subjects had 25-hydroxyvitamin D concentrations <30 nmol/L. Above that concentration, there was no dose-effect relation with physical performance except for single-leg stands. CONCLUSIONS: The factors associated with vitamin D inadequacy in Taiwan were higher education, higher BMI, and lower fish and milk intakes. No dose-effect relation existed between vitamin D concentration and physical performance except for single-leg stands. |
| 日期: | 2016-10-12 |
| 關聯: | American Journal of Clinical Nutrition. 2016 Oct 12;104(5):1334-1344. |
| Link to: | http://dx.doi.org/10.3945/ajcn.115.122804 |
| JIF/Ranking 2023: | http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0002-9165&DestApp=IC2JCR |
| Cited Times(WOS): | https://www.webofscience.com/wos/woscc/full-record/WOS:000386994500020 |
| Cited Times(Scopus): | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84994335510 |
| 顯示於類別: | [熊昭] 期刊論文
[張新儀] 期刊論文
[吳易謙] 期刊論文
[莊淑鈞] 期刊論文
[許志成] 期刊論文
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