國家衛生研究院 NHRI:Item 3990099045/10065
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 12145/12927 (94%)
造访人次 : 914787      在线人数 : 1403
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻
    主页 ‧ 登入 ‧ 上传 ‧ 说明 ‧ 关于NHRI ‧ 管理 到手机版


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/10065


    题名: Age effect on the obesity paradox in functional outcome after acute ischemic stroke - only the overweight aged show the paradox
    作者: Wu, MH;Huang, CC;Wen, CP;Hu, CJ;Hsu, CY;Taiwan Stroke Registry Investigators
    贡献者: Division of Health Policy Translation
    摘要: Background and Rationale: Obesity paradox shows that obesity and overweight are associated with increased stroke risk but reduced mortality and favorable functional outcomes in acute ischemic stroke patients. We aimed to test the age effect on the obesity paradox in functional outcome after acute ischemic stroke. Methods: With the data from the Taiwan Stroke Registry (TSR), patients of acute ischemic stroke were categorized with body mass index (BMI) as underweight (BMI <18.5), normal weight (BMI 18.5–22.9), overweight (BMI 23–27.4), and obese (BMI ≥27.5 kg/m 2 ) and divided into four age groups (20–44, 45–64, 65–74, and ≥75 years). Functional outcome was defined with modified Rankin Scale (mRS) with 0–2 as favorable and 3–5 as unfavorable, and measured 3 and 6 months after acute ischemic stroke.Results: Totally there were 26955 patients recruited for analysis. As compared within four BMI categories, overweight patients had the most favorable outcome at 3 and 6 months (OR, 0.90; 95% CI, 0.82–0.99, and 0.90; 95% CI, 0.82–0.99), while underweight patients had the worst outcome at 3 and 6 months (OR, 1.65; 95% CI, 1.34–2.04, and 1.72; 95% CI, 1.38–2.14). After stratification by age, only overweight patients with the age over 75 years had the most favorable outcome 3 and 6 months (OR, 0.86; 95% CI, 0.74–0.99, and 0.82; 95% CI, 0.70–0.95), while underweight patients had the worst functional outcome with the age over 45 years. Overweight patients with the age under 75 years or obese patients with any age group did not show better functional outcome than those with normal weight.Conclusion: In consideration of age effect on obesity paradox, only the overweight aged patients have better short-term and mid-term functional outcomes than those with normal weight after acute ischemic stroke. Underweight patients sustain the most worst functional outcome among four BMI categories.
    日期: 2016-07
    關聯: Cerebrovascular Diseases. 2016 Jul;42(Suppl.):126-128.
    Link to: http://dx.doi.org/10.1159/000447732
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1015-9770&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000381107200268
    显示于类别:[溫啟邦(2001-2010)] 會議論文/會議摘要

    文件中的档案:

    档案 描述 大小格式浏览次数
    ISI000381107200268.pdf101KbAdobe PDF468检视/开启


    在NHRI中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈