國家衛生研究院 NHRI:Item 3990099045/10221
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12145/12927 (94%)
造訪人次 : 912456      線上人數 : 1204
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/10221


    題名: A microfluidic device for single cell isolation from rare samples
    作者: Yeh, CF;He, CK;Hsu, CH
    貢獻者: Institute of Biomedical Engineering and Nanomedicine
    摘要: Increasing evidence has shown that heterogeneity in physiology and pathology have important implications for the treatment of human diseases. Single cell isolation and characterization studies are crucial for unlocking the complex regulation pathways underlying various diseases like cancer. However, to date single cell isolation still faces many challenges, especially in processing rare samples. Here, we present a novel microfluidic array chip for single cell isolation for rare samples. Our design exempts the use of long tubing, thus decreases cell loss from dead volume and allows for more accurate control of flow rate using syringe pumps during the cell capture process. Our data showed that the device significantly improved single cell capture efficiency (∼ 60 %) from small numbers of (50-500) cells in a small volume (5-10 μL). The device could be used for isolating single cells from rare samples of clinical specimens, thus potentially benefit disease diagnosis and therapy.
    日期: 2016-11-24
    關聯: 2016 IEEE 16th International Conference on Nanotechnology. 2016 Nov 24:222-223.
    Link to: http://dx.doi.org/10.1109/NANO.2016.7751366
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000391840000064
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85006873804
    顯示於類別:[許佳賢] 會議論文/會議摘要

    文件中的檔案:

    檔案 大小格式瀏覽次數
    SCP85006873804.pdf246KbAdobe PDF435檢視/開啟


    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋