國家衛生研究院 NHRI:Item 3990099045/10406

NHRI > National Institute of Cancer Research > Li-Tzong Chen > Conference Papers/Meeting Abstract > Item 3990099045/10406

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/10406

Title:	Effects of nanoliposomal irinotecan (nal-IRI;MM-398) +/- 5-fluorouracil and leucavorin (5-FU/LV) on quality of life (QoL) in patients (pts) with metastatic pancreatic adenocarcinoma (mPAC) previously treated with gemcitabine-based therapy: Results from t
Authors:	Melisi, D;Melisi, D;Siveke, JT;Blanc, J;Von Hoff, DD;Wang-Gillam, A;Chen, L;Becker, C;Mamlouk, K;De Jong, F;Hubner, R
Contributors:	National Institute of Cancer Research
Abstract:	Background: Here we report QoL results from the randomized, phase 3 NAPOLI-1 study of nal—IRI + 5—FU/LV vs 5-FU/LV alone in pts with mPDAC previously treated with gemcitabine-based therapy. Methods: QoL was assessed using the EORTC-QLQ-C30, which includes Functional, Symptom, and Global Health and QoL scales. Pts completed the questionnaire at treatment start, every 6 weeks (wks) and 30 days post-follow-up. Pts who were assessed at baseline and at ≥1 subsequent visit were included. Scores were reported in a 0–100 range after linear transformations were applied to raw scores. For each subscale, pt response was classified as improved (≥10% increase in scale of breadth at a post-baseline time point and remained above baseline for ≥6 wks), worsened (did not meet improvement criteria and died,...
Date:	2016-09
Relation:	Annals of Oncology. 2016 Sep;27(Suppl. 4):Meeting Abstract B04.
Link to:	http://dx.doi.org/10.1093/annonc/mdw333.04
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0923-7534&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000393829200053
Appears in Collections:	[Li-Tzong Chen] Conference Papers/Meeting Abstract

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