國家衛生研究院 NHRI:Item 3990099045/10766

NHRI > National Institute of Environmental Health Sciences > Yu-Cheng Chen > Periodical Articles > Item 3990099045/10766

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/10766

Title:	PM2.5 components and outpatient visits for asthma: A time-stratified case-crossover study in a suburban area
Authors:	Jung, CR;Young, LH;Hsu, HT;Lin, MY;Chen, YC;Hwang, BF;Tsai, PJ
Contributors:	National Institute of Environmental Health Sciences
Abstract:	The effects of fine particles (PM2.5) on asthma have been widely confirmed by epidemiological research studies. However, a limited number of studies have investigated the relationship between exposure to different PM2.5 components and asthma. We characterized the PM2.5 components in a suburban site of central Taiwan and conducted a time-stratified case-crossover study to elaborate the effects of daily concentration of each PM2.5 component on asthma outpatient visits. We retrieved asthma outpatient claims for individuals less than 20 years old with a residential address in the Shalu district, Taiwan, from the National Health Insurance Research Database during 2000-2010. Multiple linear regression models were used to back extrapolate the historic concentration of individual components of PM2.5 from 2000 through to 2010, including black carbon (BC) and eight ions, namely, sulfate, nitrate (NO3-), ammonium, chloride, potassium (K+), magnesium, calcium, sodium. The odds ratio (OR) with a 95% confidence interval (CI) of individual PM2.5 components on asthma was estimated by conditional logistic regression. A total of 887 asthma outpatient visits with individuals who have an average age of 7.96+/-3.88 years were selected. After adjusting for confounders, we found an interquartile range (IQR) increase in BC level, an IQR increase in NO3- level, and an IQR increase in K+ level that were all associated with the increased risk of asthma outpatient visits from the current day (OR = 1.18, 95% CI: 1.05-1.34; OR = 1.11, 95% CI: 1.01-1.21; and OR = 1.16, 95% CI: 1.04-1.30, respectively). The effects of these components on asthma were stronger in the cold season than in the warm season. However, we did not find any lagging effects. The results suggest that exposure to NO3-, BC, and K+ derived from industry-related combustion or motor vehicles emission sources may increase the risk of asthma outpatient visits, particularly during the cold season.
Date:	2017-09-12
Relation:	Environmental Pollution. 2017 Sep 12;231(Pt 1):1085-1092.
Link to:	http://dx.doi.org/10.1016/j.envpol.2017.08.102
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0269-7491&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000414881000110
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85029183672
Appears in Collections:	[Yu-Cheng Chen] Periodical Articles

Files in This Item:

File	Description	Size	Format
PUB28922715.pdf		1006Kb	Adobe PDF	382	View/Open

Loading...