國家衛生研究院 NHRI:Item 3990099045/10879

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Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/10879

Title:	Lifetime exposure to particulate air pollutants is negatively associated with lung function in non-asthmatic children
Authors:	Tsui, HC;Chen, CH;Wu, YH;Chiang, HC;Chen, BY;Guo, YL
Contributors:	National Institute of Environmental Health Sciences
Abstract:	BACKGROUND: Pulmonary function is known to be affected by acute and subacute exposure to ambient air pollution. However, the impacts of lifetime exposure to air pollution on the pulmonary function of children have been inconsistent. The present study investigated the impact of lifetime residential exposure to intermediate levels of air pollution on the pulmonary function of schoolchildren. METHODS: In 2011, a survey of children aged 6-15 years was conducted in 44 schools in Taiwan. Atopic history, residential history, and environmental factors were recorded. Spirograms were obtained from a random sample of children without asthma. A total of 535 girls and 481 boys without a history of asthma were enrolled. Lifetime residential exposure to air pollutants, including particulate matter with an aerodynamic diameter less than 10 mum (PM10), ozone (O3), sulfur dioxide (SO2), nitrogen dioxide (NO2), and carbon monoxide (CO), was estimated using the kriging method, based on monitored data from the Taiwan Environmental Protection Administration. Multiple linear regression was used to analyze the association between lifetime air pollution exposure and pulmonary function, after adjustment for potential confounders and recent exposure. RESULTS: After adjustment for 7-day average air pollutant levels, a 10 mug/m(3) increase in PM10 was related to reductions in the forced expiratory volume in 1 s (-2.00%; 95% confidence interval [CI] -3.09% to -0.90%), forced vital capacity (-1.86%; CI: -2.96% to -0.75%), and maximal midexpiratory flow (-2.28%; CI: -4.04% to -0.51%). These associations were independent of the other pollutants. CONCLUSION: Lifetime exposure to 25-85 mug/m(3) of PM10 has negative impacts on the pulmonary function of children.
Date:	2018-05
Relation:	Environmental Pollution. 2018 May;236:953-961.
Link to:	http://dx.doi.org/10.1016/j.envpol.2017.10.092
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0269-7491&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000429187500099
Cited Times(Scopus):	https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85034453608
Appears in Collections:	[Yue-Liang Guo] Periodical Articles [Hung-Che Chiang] Periodical Articles

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