國家衛生研究院 NHRI:Item 3990099045/11073
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/11073


    Title: Caged platinum nanoclusters for anticancer chemotherapeutics
    Authors: Lin, SY
    Contributors: Institute of Biomedical Engineering and Nanomedicine
    Abstract: Caged platinum nanoclusters for anticancer chemotherapeutics
    A caged platinum nanocluster complex is disclosed. The complex comprises (a) an amine-terminated dendrimer; and (b) a platinum nanocluster comprising platinum oxides, the platinum nanocluster being confined inside of the amine-terminated dendrimer. The complex exhibits cytotoxicity to cancer cells. A double-caged platinum nanocluster complex is also disclosed, which comprises polyethylene glycol (PEG) coated on the surface of a dendrimer caged platinum nanocluster complex. The double-caged caged platinum nanocluster complex comprises pH-sensitive bonds on the surface thereof. Also disclosed are methods of preparing and using the same.
    Date: 2018-02-14
    Relation: EP2958553B1/2018-02-14
    Link to: https://worldwide.espacenet.com/publicationDetails/biblio?CC=EP&NR=2958553B1&KC=B1&FT=D#
    Appears in Collections:[Shu-Yi Lin] Patents

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