國家衛生研究院 NHRI:Item 3990099045/1112

NHRI > Institute of Biotechnology and Pharmaceutical Research > Shiow-Ju Lee > Periodical Articles > Item 3990099045/1112

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/1112

Title:	Cytotoxic styrylpyrones from Goniothalamus amuyon
Authors:	Lan, YH;Chang, FR;Yu, JH;Yang, YL;Chang, YL;Lee, SJ;Wu, YC
Contributors:	Division of Biotechnology and Pharmaceutical Research
Abstract:	Two new styrylpyrones, (6R,7R,8R)-8-methoxygoniodiol (1) and (6R,7R,8R)-8-chlorogoniodiol (2), together with seven known styrylpyrones and eight other known compounds, were isolated from the leaves and/or stems of Goniothalamus amuyon. The structures of 1 and 2 were elucidated by spectral data interpretation, and the absolute stereochemistry of styrylpyrones in the diol and triol series was confirmed by X-ray crystallographic analysis and CD spectral data. Compound 2 demonstrated significant selective cytotoxicity toward the HONE-1 cancer cell line.
Keywords:	Plant Sciences;Chemistry, Applied;Chemistry, Medicinal;Pharmacology & Pharmacy
Date:	2003-04
Relation:	Journal of Natural Products. 2003 Apr;66(4):487-490.
Link to:	http://dx.doi.org/10.1021/np020441r
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0163-3864&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000182562800006
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0038674623
Appears in Collections:	[Shiow-Ju Lee] Periodical Articles

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