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http://ir.nhri.org.tw/handle/3990099045/11133
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| Title: | Increasing trends of anaphylaxis-related events: An analysis of anaphylaxis nationwide data in Taiwan, 2001-2013 |
| Authors: | Yao, TC;Huang, YW;Wu, HT;Tsai, YT;Wang, JY;Tsai, HJ |
| Contributors: | Institute of Population Health Sciences |
| Abstract: | RATIONALE: Anaphylaxis is a severe, potentially fatal, and systemic allergic reaction. Previous studies document increasing trends in the incidence and rates of anaphylaxis-related events in Western countries; however, few studies have been reported in Asian countries. We aimed to determine trends in incident rates of anaphylaxis-related events in Taiwan from 2001 through 2013. METHODS: We utilized medical claims data from the National Health Insurance Research Database in Taiwan. We identified anaphylaxis-related events and calculated incident rates, accordingly. Regression-based analyses were applied to examine trends and incident rates across study years. RESULTS: A total of 2,496 patients with first-time anaphylaxis were identified. The mean (standard deviation) age was 45.11 (20.64) years, and 56% of patients were male. The overall incident rate of anaphylaxis-related outpatient events was 6.94 (95% CI 5 6.77-7.22) per 100,000 person-years. When stratifying by age, significant increasing incident rates were observed among subjects aged < 18, 19-39, and 40-59 years (all p _ trend < 0.01), but not among subjects aged > 60 years. Among 2,496 patients, 1,696 (68.0%) patients were identified only from outpatient or emergency department (ED) visits, 495 (19.8%) patients were hospitalized, and 305 (12.2%) hospitalized patients were admitted to intensive care units. Furthermore, time trend of anaphylaxis-related outpatient or ED visits has increased over time ( p _trend 5 0.01), but time trend of anaphylaxisrelated hospitalization has decreased over time ( p _trend < 0.01). CONCLUSIONS: In this study, we observed the increasing incident rate of anaphylaxis-related events over time. The increasing incident rates were associated with different age groups, but not among subjects aged > 60 years. |
| Date: | 2018-02 |
| Relation: | Journal of Allergy and Clinical Immunology. 2018 Feb;141(2, Suppl.):AB153. |
| Link to: | https://doi.org/10.1016/j.jaci.2017.12.489 |
| JIF/Ranking 2023: | http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0091-6749&DestApp=IC2JCR |
| Cited Times(WOS): | https://www.webofscience.com/wos/woscc/full-record/WOS:000429306700484 |
| Appears in Collections: | [蔡慧如] 會議論文/會議摘要
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Files in This Item:
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Size | Format | |
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| ISI000429306700484.pdf | | 125Kb | Adobe PDF | 269 | View/Open |
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