國家衛生研究院 NHRI:Item 3990099045/1115
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    题名: Coumarinolignans from the root of Formosan Antidesma pentandrum var. barbatum
    作者: Chen, YC;Cheng, MJ;Lee, SJ;Dixit, AK;Ishikawa, T;Tsai, IL;Chen, IS
    贡献者: Division of Biotechnology and Pharmaceutical Research
    摘要: Four new coumarinolignans, antidesmanin A (=7-(1,1-dimethylallyl)-2,3-dihydro-3-(4-hydroxy-3,5-dimethoxvphenyl)-10-methoxy-2-methyl-6H-1,4,5-trioxaphenanthren-6-one; 1), antidesmanin B (=3,7-bis(1,1-dimethylallyl)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-10-methoxy-6H-1,4,5-trioxaphenanthren-6-one; 2), antidesmanin C (=2,7-bis-(1,1-dimethylallyl)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-10-methoxy-6H-1,4,5-trioxaphenanthren-6-one; 3) and antidesmanin D (=2-(3,4-dihydroxyphenyl)-3,7-bis(1,1-dimethylallyl)2,3-dihydroxy-10-methoxy-6H-1,4,5-trioxaphenanthren-6-one or 3-(3,4-dihydroxyphenyl)-2,7-bis(1,1-dimethylallyl)-2,3-dihydro-10-methoxy-6H-1,4,5-trioxaphenanthren-6-one; 4) have been isolated from the root of the Formosan Antidesma pentandrum var. barbatum. The structures of these new compounds were elucidated by spectroscopic data. Compounds 1-3 exhibited marginal cytotoxicity against MCF-7 (breast) and SF-268 (CNS) cancer cell lines in vitro.
    关键词: Chemistry, Multidisciplinary
    日期: 2004
    關聯: Helvetica Chimica Acta. 2004;87(11):2805-2811.
    Link to: http://dx.doi.org/10.1002/hlca.200490251
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0018-019X&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000225653800007
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=11144326763
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