國家衛生研究院 NHRI:Item 3990099045/11205

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Title:	Generation of hanging drops with defined solution concentrations using a sliding hanging drop chip
Other Titles:	Proceedings IEEE Micro Electro Mechanical Systems
Authors:	Tang, CY;Fu, CC;Hsu, CH
Contributors:	Institute of Biomedical Engineering and Nanomedicine
Abstract:	Traditionally, hanging drop method has been widely used for three-dimensional (3D) cell sphere culture, which in comparison to two-dimensional (2D) cell culture provides a cell culture environment to better mimic the in vivo conditions. Recently, it has been shown that microfluidic technology can provide attractive tools for hanging drop cell culture due to its ability of handling low volume liquid and potential of building high-throughput systems. In this paper, we present a new approach which can be used to build a simplified hanging drop chip system integrated with drug testing function. Without using other external equipment, cell culture and drug application processes can be easily done by using a conventional pipette and sliding the chip.
Date:	2018-04-26
Relation:	2018 IEEE Micro Electro Mechanical Systems. 2018 Apr 26:1161-1164.
Link to:	http://dx.doi.org/10.1109/MEMSYS.2018.8346768
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000434960900303
Appears in Collections:	[Chia-Hsien Hsu] Conference Papers/Meeting Abstract

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