國家衛生研究院 NHRI:Item 3990099045/11206
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    题名: Development of a MRI-compatible high-intensity focused ultrasound phased array transducer dedicated for breast tumor treatment
    作者: Kuo, L;Chiu, L;Lin, W;Chen, J;Dong, G;Chen, S;Chen, G
    贡献者: Institute of Biomedical Engineering and Nanomedicine
    摘要: High-intensity focused ultrasound under MRI guidance can achieve a noninvasive and precise ablation of the solid tumor. In the study, a MRI-compatible 1-MHz 16-channel ring-shaped transducer was developed to minimize the burn risk of breast skin and perform volumetric ablation for short treatment time. The measured electroacoustic conversion efficiency of the transducer was 50.90 5. The transducer could produce a point and a quasi-hollow-cylinder lesion in a thermal-sensitive phantom or an ex vivo pork by tuning the phase of each element. It may achieve volumetric ablation of 1.5 cm3 when the point lesion is located inside the hollow lesion. Ex-vivo ablation experiments showed that the transducer could cause a coagulative necrosis in the pork from the surrounded subcutaneous fat by 5 mm without fat damage. The temperature and region of the pork ablation were quantified by MRI technique. There was no MRI interference from HIFU and vice versa while both systems operated concurrently.
    日期: 2018-08
    關聯: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 2018 Aug;65(8):1423-1432.
    Link to: http://dx.doi.org/10.1109/TUFFC.2018.2841418
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0885-3010&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000440351400011
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85047985448
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