Research has reported heterogeneity in longitudinal wheezing patterns arising in childhood. Data-driven approaches have also identified 4 wheezing trajectory phenotypes in childhood asthma in 2 longitudinal cohorts when the types of transient early and prolonged early wheezing were grouped together. However, a large-scale study following patients from birth to the age of 10 years revealed 3 asthma trajectory phenotypes.
Date:
2018-12
Relation:
Pediatric Allergy and Immunology. 2018 Dec;29(8):873-877.