國家衛生研究院 NHRI:Item 3990099045/11424
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    题名: Body mass index and fat mass index in relation to atopy in school children
    作者: Lin, C;Fang, H;Tsai, Z;Chiu, C;Huang, Y;Huang, Y;Lu, K;Kao, P;Lee, W;Gau, C;Tsai, H;Yao, T
    贡献者: Institute of Population Health Sciences
    摘要: Background: It has been noticed that body mass index (BMI) may not be a good measurement to define obesity in pediatric populations compared to adult populations. In addition, the association between obesity and atopy remains unclear. In this study, we aimed to examine the associations of BMI and total body fat mass index (FMI), respectively, with atopy in school children. Method: The study included a total of 613 children born in 2010‐2011 and participated in the Longitudinal Investigation of Global Health in Taiwanese Schoolchildren (LIGHTS) cohort. We measured BMI (weight/height2) and FMI (total body fat mass/height2). BMI and FMI were transformed into Z‐scores, respectively, to enable comparison of the effect sizes between BMI and FMI. Atopy (also known as allergic sensitization) was defined as a positive Phadiatop Infant test result (≧0.35 PAU/L). We adjusted potential confounding factors such as exposure to birth weight, breast feeding, activity time, environmental tobacco smoke, maternal smoking during pregnancy, parental education, and family incomes, which were obtained from a modified International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. We applied multiple logistic regression to examine the associations of BMI or FMI with atopy. Results: The results showed higher FMI Z‐score was associated with increased risk of atopy (adjusted odds ratio (AOR) = 1.35; 95% CI = 1.08‐1.70; P = 0.009). When categorized FMI into three groups (>85th percentile; 15th‐85th percentile; and <15th percentile), children in the group of >85th percentile was significantly associated with increased risk of atopy (AOR = 1.63; 95% CI = 1.07‐2.48; P = 0.02), compared with those in the group of <15th percentile. In contrast, BMI was not associated with atopy, neither BMI Z‐score nor categorized BMI. Conclusion: The results demonstrate positive association between FMI and atopy in the study children. FMI might serve as a better indicator than BMI in childhood obesity research.
    日期: 2018-08
    關聯: Allergy. 2018 Aug;73(Suppl. 105):169.
    Link to: http://dx.doi.org/10.1111/all.13537
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0105-4538&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000441690401074
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