國家衛生研究院 NHRI:Item 3990099045/11665
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 12145/12927 (94%)
造访人次 : 859736      在线人数 : 798
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻
    主页 ‧ 登入 ‧ 上传 ‧ 说明 ‧ 关于NHRI ‧ 管理 到手机版


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/11665


    题名: Non-smoking COPD: An overlooked systemic disease, modifiable by physical activity based on studying a cohort of 386,304 subjects
    作者: Shu, CC;Su, TC;Lee, JH;Tsai, MK;Wen, CP
    贡献者: Institute of Population Health Sciences
    摘要: Background: Smoking cessation is the mainstay treatment for COPD among smokers, but, for nonsmoking COPD, effective management beyond symptomatic treatment is still unsettled. Methods: A cohort of 386,304 adults in Taiwan went through health surveillance program between 1994 and 2008, with health data collected including spirometry and medical and lifestyle history. Fully active individuals exercised 30 min/day at 4 MET intensity. A total of 16,089 COPD, 4.2% of the cohort, was defined by GOLD with FVC/FEV1 <0.70. More than half (62%) of COPD were nonsmokers. COPD deaths, 1527 out of 10,743, were identified as of 2008 from National Death File by matching with cohort IDs. Hazard ratios (HR) used Cox model. Results: Hazard ratios of non-smoking COPD were significantly increased for specific cause of death such as COPD (HR:11.86) but also from all-cause (1.44), CVD (1.68) including heart (1.55) and stroke (1.69), and Kidney diseases (2.06), a sign of systemic extra-pulmonary involvement. The significant increase of all-cause risk of COPD (1.44) became non-significant when these COPD became fully active, compared to inactive non-COPD (1.08, 95%CI: 0.9 – 1.3), implying that COPD risks could be eliminated through physical activity. Conclusions: Non-smoking COPD, a sizable majority among all COPDs in this Asian cohort, is a systemic disease with multi-system extra-pulmonary involvement. Their mortality risks disappeared in the long run by those COPDs engaged in regular exercise of at least 30 min/day of moderate intensity.
    日期: 2018-09
    關聯: European Respiratory Journal. 2018 Sep;52(Suppl. 62):Meeting Abstract PA762.
    Link to: http://dx.doi.org/10.1183/13993003.congress-2018.PA762
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0903-1936&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000455567107442
    显示于类别:[溫啟邦(2001-2010)] 會議論文/會議摘要

    文件中的档案:

    没有与此文件相关的档案.



    在NHRI中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈