國家衛生研究院 NHRI:Item 3990099045/11694
English  |  正體中文  |  简体中文  |  Items with full text/Total items : 12145/12927 (94%)
Visitors : 907270      Online Users : 906
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
    •  Adv. Search
    Home ‧ Login ‧ Upload ‧ Help ‧ About ‧ Administer Goto mobile version


    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/11694


    Title: Oral hygiene and the survival of head and neck cancer
    Authors: Chang, JS;Hsiao, JR
    Contributors: National Institute of Cancer Research
    Abstract: Poor oral hygiene is an established risk factor of head and neck cancer (HNC); however, its role in the survival of HNC is unclear. We investigated the association between oral hygiene habits, including regular dental visits, frequency of tooth brushing, and use of dental floss, and the overall survival (OS) of HNC using interview data collected from 740 HNC patients. We found that poor oral hygiene was significantly associated with a worse OS of HNC (hazard ratio (HR) = 1.38, 95% confidence interval (CI): 1.03-1.86). Furthermore, this relationship was modified by the single nucleotide polymorphism, rs11536889, of TLR4. A strong association between poor oral hygiene and a worse survival of HNC was observed among those with the CG or CC genotype (HR = 2.32, 95% CI: 1.41-3.82) but not among those with the GG genotype (HR = 0.95, 95% CI: 0.65-1.40). Overall, our results indicated that poor oral hygiene, a risk factor of HNC, may also be a prognostic factor of HNC. More investigations are needed to determine the biological mechanisms to explain the worse HNC survival associated with poor oral hygiene.
    Date: 2018-12
    Relation: Cancer Science. 2018 Dec;109(Suppl. 2):1437.
    Link to: https://doi.org/10.1111/cas.13904
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1347-9032&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000453773606461
    Appears in Collections:[Jeffrey Shu-Ming] Conference Papers/Meeting Abstract

    Files in This Item:

    File SizeFormat
    ISI000453773606461.pdf35KbAdobe PDF102View/Open


    All items in NHRI are protected by copyright, with all rights reserved.

    Related Items in TAIR

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback