| 2024-06 |
UHRF1P contributes to IL-17A-mediated systemic lupus erythematosus via UHRF1-MAP4K3 axis |
Journal of Autoimmunity. 2024 Jun;146:Article number 103221. |
 |
| 2024-03-27 |
Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating Lck |
Journal of Biomedical Science. 2024 Mar 27;31:Article number 33. |
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| 2024-01-15 |
The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling |
Nature Communications. 2024 Jan 15;15:Article number 532. |
|
| 2023-12-05 |
Dual-specificity phosphatase 6 deficiency attenuates arterial-injury-induced intimal hyperplasia in mice |
International Journal of Molecular Sciences. 2023 Dec 05;24(24):Article number 17136. |
|
| 2023-11-01 |
DUSP8 induces TGF-beta–stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-Alpha |
Journal of Clinical Investigation. 2023 Nov 01;133(21):Article number e166269. |
|
| 2023-08-22 |
ACE2 in chronic disease and COVID-19: Gene regulation and post-translational modification |
Journal of Biomedical Science. 2023 Aug 22;30:Article number 71. |
|
| 2023-05-01 |
DUSP8 induces TGF-Beta-stimulated IL-9 transcription and Th9-mediated immune responses by inactivating a transcriptional repressor |
Journal of Immunology. 2023 May 01;210(Suppl. 1):Abstract number 243.04. |
|
| 2023-04-22 |
DUSP6 deficiency attenuates neurodegeneration after global cerebral ischemia |
International Journal of Molecular Sciences. 2023 Apr 22;24(9):Article number 7690. |
|
| 2023-02-10 |
Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis |
BMC Medicine. 2023 Feb 10;21:Article number 46. |
|
| 2022-07-27 |
SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19 |
EMBO Molecular Medicine. 2022 Jul 27:Article number e15904. |
|
| 2022-07-18 |
MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKK beta and inducing IKK beta-mediated FoxO1 nuclear export and Foxp3 downregulation |
Theranostics. 2022 Jul 18;12(12):5744-5760. |
|
| 2022-02-18 |
Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice |
iScience. 2022 Feb 18;25(2):Article number 103738. |
|
| 2022-02 |
Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus |
Annals of the Rheumatic Diseases. 2022 Feb;81(2):243-254. |
|
| 2022-01 |
Induction of interferon-gamma and tissue inflammation by overexpression of eosinophil cationic protein in T cells and exosomes |
Arthritis and Rheumatology. 2022 Jan;74(1):92-104. |
|
| 2021-10-25 |
BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus |
Theranostics. 2021 Oct 25;11(20):9953-9966. |
|
| 2020-10-12 |
Structural insights into the active site formation of dusp22 in n-loop-containing protein tyrosine phosphatases |
International Journal of Molecular Sciences. 2020 Oct 12;21(20):Article number 7515. |
|
| 2020-08-12 |
DUSP11 attenuates lipopolysaccharide-induced macrophage activation by targeting TAK1 |
Journal of Immunology. 2020 Aug 12;205(6):1644-1652. |
|
| 2019-11-13 |
MAP4K family kinases and DUSP family phosphatases in T-Cell signaling and systemic lupus erythematosus |
Cells. 2019 Nov 13;8(11):Article number 1433. |
|
| 2019-10-22 |
MAP4K3/GLK in autoimmune disease, cancer and aging |
Journal of Biomedical Science. 2019 Oct 22;26:Article number 82. |
|
| 2019-10 |
AhR-ROR-gammat complex is a therapeutic target for MAP4K3/GLK(high)IL-17A(high) subpopulation of systemic lupus erythematosus |
FASEB Journal. 2019 Oct;3(10):11469-11480. |
|
| 2019-10 |
MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1 |
Cancer Research. 2019 Oct;79(19):4978-4993. |
|
| 2019-05-30 |
Regulation of Dual-Specificity Phosphatase (DUSP) ubiquitination and protein stability |
International Journal of Molecular Sciences. 2019 May 30;20(11):Article number 2668. |
|
| 2019-05 |
MAP4K3/GLK-induced AhR-RORyt complex is a novel therapeutic target for GLIC(high)IL-17A(high) subpopulation of SLE patients |
Journal of Immunology. 2019 May;202(1, Suppl. S):Meeting Abstract 132.2. |
|
| 2019-05 |
T-cell signaling in Th17-mediated inflammation |
Journal of Immunology. 2019 May;202(1, Suppl. S):Meeting Abstract 124.7. |
|
| 2018-12 |
RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell |
Biochimica et Biophysica Acta-Molecular Cell Research. 2018 Feb;1865(2):259-272. |
|
| 2018-12 |
Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation |
FASEB Journal. 2018 Dec;32(12):6760-6770. |
|
| 2018-09-12 |
GLK-IKKbeta signaling induces dimerization and translocation of the AhR-RORgammat complex in IL-17A induction and autoimmune disease |
Science Advances. 2018 Sep 12;4(9):Article number eaat5401. |
|
| 2018-09-06 |
RBM4A-SRSF3-MAP4K4 splicing cascade constitutes a molecular mechanism for regulating brown adipogenesis |
International Journal of Molecular Sciences. 2018 Sep 6;19(9):Article number 2646. |
|
| 2018 |
MAP4K3 (GLK) |
Encyclopedia of Signaling Molecules. 2018 :2947-2951. |
|
| 2017-11 |
Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration |
Oncogene. 2017 Nov;36(47):6509-6517. |
|
| 2017-01-07 |
MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes |
Journal of Biomedical Science. 2017 Jan 7;24:Article number 4. |
|
| 2016-08 |
Downregulation of the phosphatase JKAP/DUSP22 in T Cells as a potential new biomarker of systemic lupus erythematosus nephritis |
Oncotarget. 2016 Aug;7(36):57593-57605. |
|
| 2016-08 |
Roles of innate immune regulator TAPE in RIG-I signaling and antiviral defenses |
European Journal of Immunology. 2016 Aug;46(Suppl. 1):569. |
|
| 2016-08 |
Emerging roles of an innate immune regulator TAPE in Toll-like receptors, RIG-I-like receptors, and beyond |
European Journal of Immunology. 2016 Aug;46(Suppl. 1):646. |
|
| 2016-08 |
HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to T-cell-mediated type 2 diabetes |
European Journal of Immunology. 2016 Aug;46(Suppl. 1):84-85. |
|
| 2016-07 |
GLK/MAP4K3 overexpression associates with recurrence risk for non-small cell lung cancer |
Oncotarget. 2016 Jul;7(27):41748-41757. |
|
| 2016-07 |
Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase |
Oncotarget. 2016 Jul;7(31):49765-49776. |
|
| 2016-05 |
Roles of innate immune regulator TAPE in RIG-I signaling and antiviral defenses |
Journal of Immunology. 2016 May;196(1 Suppl.) :Abstract number 203.13. |
|
| 2016-05 |
Emerging roles of an innate immune regulator TAPE in Toll-like receptors, RIG-I-like receptors, and beyond |
Journal of Immunology. 2016 May;196(1 Suppl.):Meeting Abstract 202.35. |
|
| 2016-03-08 |
Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients |
Oncotarget. 2016 Mar 8;7(10):10976-10989. |
|
| 2016-01 |
MAP4K family kinases in immunity and inflammation |
Advances in Immunology. 2016 Jan;129:277-314. |
|
| 2014-09-30 |
Map kinase kinase kinase kinase 3 (MAP4K3) as a biomarker and therapeutic target for autoimmune disease, cancer, inflammation and IL-17-associated disease |
US8846311/2014-09-30 |
|
| 2014-08-06 |
HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance |
Nature Communications. 2014 Aug 6;5:Article number 4602. |
|
| 2014-04-09 |
The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck |
Nature Communications. 2014 Apr 9;5:Article number 3618. |
|
| 2014-02-15 |
Dual-specificity Phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation |
Journal of Immunology. 2014 Feb 15;192(4):1547-1557. |
|
| 2013-10 |
Germinal center kinase-like kinase overexpression in T cells as a novel biomarker in rheumatoid arthritis |
Arthritis and Rheumatism. 2013 Oct;65(10):2573-2582. |
|
| 2012-08-06 |
Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker |
BMC Medicine. 2012 Aug 6;10(1):Article number 84. |
|
| 2012-07 |
Regulation of PKC-theta function by phosphorylation in T cell receptor signaling |
Frontiers in Immunology. 2012 Jul;3:Article number 197. |
|
| 2011-10 |
The kinase GLK controls autoimmunity and NF-kappa B signaling by activating the kinase PKC-theta in T cells |
Nature Immunology. 2011 Oct;12(11):1113-1118. |
|
| 2009-06 |
Enhanced expression of vascular endothelial growth factor-A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis |
Hepatology. 2009 Jun;49(6):1962-1971. |
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