國家衛生研究院 NHRI:
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    近3年内发表的文件:14(21.54%)
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    日期题名關聯
    2024-09 The role of dual specificity phosphatase 22 (DUSP22) in rheumatoid arthritis: Mechanism and genetic investigations Arthritis and Rheumatology. 2024 Sep;76:75-76.
    2024-06 UHRF1P contributes to IL-17A-mediated systemic lupus erythematosus via UHRF1-MAP4K3 axis Journal of Autoimmunity. 2024 Jun;146:Article number 103221.
    2024-05-01 Sequential regulation of Lck K63-ubiquitination and autophosphorylation by the E3 ligase UBR2 and the phosphatase DUSP22 in TCR signaling Journal of Immunology. 2024 May 01;212(1, Suppl.):Meeting Abstract 0220_5352.
    2024-05-01 DUSP8 promotes IL-9 transcription by inactivating Pur-alpha leading to asthma and atopic dermatitis Journal of Immunology. 2024 May 01;212(1, Suppl.):Meeting Abstract 0608_4827.
    2024-05-01 Machine learning reveals UHRF-X as a biomarker for systemic lupus erythematosus and an antagonistic protein against UHRF1 E3 ligase Journal of Immunology. 2024 May 01;212(1, Suppl.):Meeting Abstract 020-5291.
    2024-03-27 Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating Lck Journal of Biomedical Science. 2024 Mar 27;31:Article number 33.
    2024-01-15 The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling Nature Communications. 2024 Jan 15;15:Article number 532.
    2023-12-05 Dual-specificity phosphatase 6 deficiency attenuates arterial-injury-induced intimal hyperplasia in mice International Journal of Molecular Sciences. 2023 Dec 05;24(24):Article number 17136.
    2023-11-01 DUSP8 induces TGF-beta–stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-Alpha Journal of Clinical Investigation. 2023 Nov 01;133(21):Article number e166269.
    2023-08-22 ACE2 in chronic disease and COVID-19: Gene regulation and post-translational modification Journal of Biomedical Science. 2023 Aug 22;30:Article number 71.
    2023-06-11 作為用於自體免疫疾病及IL-17 相關疾病之生物標記及治療標靶之AhR-ROR-γt 複合體 TWI804669/2023-06-11
    2023-05-01 DUSP8 induces TGF-Beta-stimulated IL-9 transcription and Th9-mediated immune responses by inactivating a transcriptional repressor Journal of Immunology. 2023 May 01;210(Suppl. 1):Abstract number 243.04.
    2023-04-22 DUSP6 deficiency attenuates neurodegeneration after global cerebral ischemia International Journal of Molecular Sciences. 2023 Apr 22;24(9):Article number 7690.
    2023-02-10 Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis BMC Medicine. 2023 Feb 10;21:Article number 46.
    2022-07-27 SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19 EMBO Molecular Medicine. 2022 Jul 27:Article number e15904.
    2022-07-18 MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKK beta and inducing IKK beta-mediated FoxO1 nuclear export and Foxp3 downregulation Theranostics. 2022 Jul 18;12(12):5744-5760.
    2022-06-14 AhR-ROR-γt complex as a biomarker and therapeutic target for autoimmune disease and IL-17A-associated disease US11360080/2022-06-14
    2022-02-18 Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice iScience. 2022 Feb 18;25(2):Article number 103738.
    2022-02 Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus Annals of the Rheumatic Diseases. 2022 Feb;81(2):243-254.
    2022-01 Induction of interferon-gamma and tissue inflammation by overexpression of eosinophil cationic protein in T cells and exosomes Arthritis and Rheumatology. 2022 Jan;74(1):92-104.
    2021-10-25 BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus Theranostics. 2021 Oct 25;11(20):9953-9966.
    2020-10-12 Structural insights into the active site formation of dusp22 in n-loop-containing protein tyrosine phosphatases International Journal of Molecular Sciences. 2020 Oct 12;21(20):Article number 7515.
    2020-08-12 DUSP11 attenuates lipopolysaccharide-induced macrophage activation by targeting TAK1 Journal of Immunology. 2020 Aug 12;205(6):1644-1652.
    2019-11-13 MAP4K family kinases and DUSP family phosphatases in T-Cell signaling and systemic lupus erythematosus Cells. 2019 Nov 13;8(11):Article number 1433.
    2019-10-22 MAP4K3/GLK in autoimmune disease, cancer and aging Journal of Biomedical Science. 2019 Oct 22;26:Article number 82.

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