國家衛生研究院 NHRI:Item 3990099045/12334
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    题名: Changes in the relationship between ambient fine particle concentrations and childhood lung function over 5 years
    作者: Chen, BY;Chen, CH;Chuang, YC;Wu, YH;Pan, SC;Guo, YL
    贡献者: National Institute of Environmental Health Sciences
    摘要: BACKGROUND: Exposure to ambient fine particles, particulate matter with an aerodynamic diameter of </=2.5mum (PM2.5), is a public health concern. Concentrations of ambient PM2.5 have changed temporally in the past 10 years after a series of action policies for improving air quality were implemented in Taiwan. In this study, temporal changes in the relationship between PM2.5 and lung function among children were investigated. METHODS: A nationwide respiratory health survey was conducted among Taiwanese elementary and middle school students in 2011 and again in 2016-2017. A questionnaire was administered to students, for whom forced vital capacity (FVC) and forced expiratory volume in 1s (FEV1) were measured using spirometry. During the study period, monthly concentrations of ambient PM2.5 were obtained from the monitoring stations of the Environmental Protection Administration. Lung function measurements were compared with ambient PM2.5 exposure using mixed-effects models. RESULTS: In the 2011 survey (mean PM2.5: 40.6mug/m(3)), exposure to PM2.5 in the preceding 1-2 months was associated with a 2.2% decrease (95% confidence interval [CI]: -4.1%, -0.3%) in FVC and a 2.3% decrease (95% CI: -4.0%, -0.5%) in FEV1. By contrast, a significant relationship between PM2.5 concentrations and lung function was not observed in the 2016-2017 survey (mean PM2.5: 30.0mug/m(3)). CONCLUSIONS: As improvement in air quality over time, the negative relationship between PM2.5 and childhood lung function tend to be not significant.
    日期: 2019-12
    關聯: Environmental Research. 2019 Dec;179(Pt B):Article number 108809.
    Link to: http://dx.doi.org/10.1016/j.envres.2019.108809
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0013-9351&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000502685500008
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85074152442
    显示于类别:[郭育良] 期刊論文
    [陳秉鈺] 期刊論文

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