國家衛生研究院 NHRI:Item 3990099045/12387
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/12387


    Title: Long-term ambient hydrocarbons exposure and incidence of ischemic stroke
    Authors: Zhang, HW;Kok, VC;Chuang, SC;Tseng, CH;Lin, CT;Li, TC;Sung, FC;Wen, CP;Hsiung, CA;Hsu, CY
    Contributors: Institute of Population Health Sciences
    Abstract: Exposure to air pollutants is known to have adverse effects on human health; however, little is known about the association between hydrocarbons in air and an ischemic stroke (IS) event. We investigated whether long-term exposure to airborne hydrocarbons, including volatile organic compounds, increased IS risk. This retrospective cohort study included 283,666 people aged 40 years or older in Taiwan. Cox proportional hazards regression analysis was used to fit single- and multiple-pollutant models for two targeted pollutants, total hydrocarbons (THC) and nonmethane hydrocarbons (NMHC), and estimated the risk of IS. Before controlling for multiple pollutants, hazard ratios (HRs) of IS with 95% confidence intervals for the overall population were 2.69 (2.64-2.74) at 0.16-ppm increase in THC and 1.62 (1.59-1.66) at 0.11-ppm increase in NMHC. For the multiple-pollutant models controlling for PM2.5, the adjusted HR was 3.64 (3.56-3.72) for THC and 2.21 (2.16-2.26) for NMHC. Our findings suggest that long-term exposure to THC and NMHC may be a risk factor for IS development.
    Date: 2019-12-04
    Relation: PLoS ONE. 2019 Dec 4;14(12):Article number e0225363.
    Link to: http://dx.doi.org/10.1371/journal.pone.0225363
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1932-6203&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000533987600022
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85076035849
    Appears in Collections:[Chao A. Hsiung] Periodical Articles
    [Chi-Pang Wen(2001-2010)] Periodical Articles
    [Shu-Chun Chuang] Periodical Articles

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