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Please use this identifier to cite or link to this item:
http://ir.nhri.org.tw/handle/3990099045/12424
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| Title: | Individualized home-based exercise and nutrition interventions improve frailty in older adults: A randomized controlled trial |
| Authors: | Hsieh, TJ;Su, SC;Chen, CW;Kang, YW;Hu, MH;Hsu, LL;Wu, SY;Chen, L;Chang, HY;Chuang, SY;Pan, WH;Hsu, CC |
| Contributors: | Institute of Population Health Sciences |
| Abstract: | Background Frail older adults are predisposed to multiple comorbidities and adverse events. Recent interventional studies have shown that frailty can be improved and managed. In this study, effective individualized home-based exercise and nutrition interventions were developed for reducing frailty in older adults. Methods This study was a four-arm, single-blind, randomized controlled trial conducted between October 2015 and June 2017 at Miaoli General Hospital in Taiwan. Overall, 319 pre-frail or frail older adults were randomly assigned into one of the four study groups (control, exercise, nutrition, and exercise plus nutrition [combination]) and followed up during a 3-month intervention period and 3-month self-maintenance period. Improvement in frailty scores was the primary outcome. Secondary outcomes included improvements in physical performance and mental health. The measurements were performed at baseline, 1 month, 3 months, and 6 months. Results At the 6-month measurement, the exercise (difference in frailty score change from baseline: - 0.23; 95% confidence interval [CI]: - 0.41, - 0.05; p = 0.012), nutrition (- 0.28; 95% CI: - 0.46, - 0.11; p = 0.002), and combination (- 0.34; 95% CI: - 0.52, - 0.16; p < 0.001) groups exhibited significantly greater improvements in the frailty scores than the control group. Significant improvements were also observed in several physical performance parameters in the exercise, nutrition, and combination groups, as well as in the 12-Item Short Form Health Survey mental component summary score for the nutrition group. Conclusions The designated home-based exercise and nutrition interventions can help pre-frail or frail older adults to improve their frailty score and physical performance. |
| Date: | 2019-12 |
| Relation: | International Journal of Behavioral Nutrition and Physical Activity. 2019 Dec;16:Article number 119. |
| Link to: | http://dx.doi.org/10.1186/s12966-019-0855-9 |
| JIF/Ranking 2023: | http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1479-5868&DestApp=IC2JCR |
| Cited Times(WOS): | https://www.webofscience.com/wos/woscc/full-record/WOS:000500990100001 |
| Cited Times(Scopus): | https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85075845521 |
| Appears in Collections: | [許志成] 期刊論文
[潘文涵] 期刊論文
[莊紹源] 期刊論文
[張新儀] 期刊論文
[陳麗光] 期刊論文
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| ISI000500990100001.pdf | | 861Kb | Adobe PDF | 454 | View/Open |
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