國家衛生研究院 NHRI:Item 3990099045/12542

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Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/12542

Title:	Prevalence and molecular characterizations of Staphylococcus aureus nasal colonization among patients in pediatric intensive care units in Taiwan
Authors:	Chen, YH;Huang, KA;Huang, YC;Chi, H;Lu, CY;Chang, LY;Ho, YH;Chi, CY;Liu, CC;Huang, LM;Yang, TYO;Huang, YC
Contributors:	National Institute of Infectious Diseases and Vaccinology
Abstract:	BACKGROUND: Nasal colonization of Staphylococcus aureus is a risk factor for the pathogen transmission and the development of infections. Limited information is available on the prevalence and molecular characteristics of S. aureus colonization in pediatric intensive care unit (ICU) patients. METHODS: A cross-sectional, island-wide study was conducted in 2011. Nasal swabs were collected from pediatric ICU patients at six tertiary hospitals in Taiwan. RESULTS: Of 114 patients enrolled in total, nasal colonization of S. arueus was detected in 30 (26.3%) of them, among whom 20 (17.5%) with methicillin-resistant S. arueus (MRSA). The ST59/SCCmec IV and V clones were most common and accounted for 45% of MRSA isolates, followed by ST239/SCCmec III (25%) and ST45/SCCmec IV (20%) clones. Three ST59 MRSA isolates carried the Panton-Valentine Leukocidin genes. CONCLUSIONS: The results indicated a high prevalence of S. arueus and MRSA nasal colonization among pediatric ICU patients in Taiwan. Identification of epidemic clones warrants the implement of infection control measures to reduce colonization and prevent the dissemination of MRSA in hospitals.
Date:	2020-02-27
Relation:	Antimicrobial Resistance and Infection Control. 2020 Feb 27;9:Article number 41.
Link to:	http://dx.doi.org/10.1186/s13756-020-0700-6
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=2047-2994&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000520434000001
Cited Times(Scopus):	https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85081285126
Appears in Collections:	[Chia-Yu Chi] Periodical Articles

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