國家衛生研究院 NHRI:Item 3990099045/12603
English  |  正體中文  |  简体中文  |  Items with full text/Total items : 12145/12927 (94%)
Visitors : 907455      Online Users : 952
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
    •  Adv. Search
    Home ‧ Login ‧ Upload ‧ Help ‧ About ‧ Administer Goto mobile version


    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/12603


    Title: Enhancement of neurite outgrowth by warming biomaterial ultrasound treatment
    Authors: Chen, JC;Su, CM;Chen, GS;Lai, CC;Chen, CY;Lin, KM;Lin, FH;Dong, GC
    Contributors: Institute of Biomedical Engineering and Nanomedicine
    Abstract: Ultrasound is a method for enhancing neurite outgrowth because of its thermal effect. In order to reach the working temperature to enhance neurite outgrowth, long-time treatment by ultrasound is necessary, while acknowledging that the treatment poses a high risk of damaging nerve cells. To overcome this problem, we developed a method that shortens the ultrasonic treatment time with a warming biomaterial. In this study, we used Fe3O4 nanoparticle-embedded polycaprolactone (PCL) as a sonosensitized biomaterial, which has an excellent heating rate due to its high acoustic attenuation. With this material, the ultrasonic treatment time for enhancing neurite outgrowth could be effectively shortened. Ultrasonic treatment could also increase neuronal function combined with the warming biomaterial, with more promoter neuronal function than only ultrasound. Moreover, the risk of overexposure can be avoided by the use of the warming biomaterial by reducing the ultrasonic treatment time, providing better effectiveness.
    Date: 2020-03-23
    Relation: International Journal of Molecular Sciences. 2020 Mar 23;21(6):Article number 2236.
    Link to: http://dx.doi.org/10.3390/ijms21062236
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1422-0067&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000529890200332
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85082380009
    Appears in Collections:[Gin-Shin Chen] Periodical Articles
    [Kurt Ming-Chao Lin] Periodical Articles
    [Feng-Huei Lin] Periodical Articles
    [Guo-Chung Dong] Periodical Articles

    Files in This Item:

    File Description SizeFormat
    PUB32210196.pdf4381KbAdobe PDF424View/Open


    All items in NHRI are protected by copyright, with all rights reserved.

    Related Items in TAIR

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback