國家衛生研究院 NHRI:Item 3990099045/12740
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    题名: Immunologic aspects of characteristics, diagnosis, and treatment of coronavirus disease 2019 (COVID-19)
    作者: Chang, FY;Chen, HC;Chen, PJ;Ho, MS;Hsieh, SL;Lin, JC;Liu, FT;Sytwu, HK
    贡献者: National Institute of Infectious Diseases and Vaccinology
    摘要: On March 11, 2020, the World Health Organization declared the worldwide spread of the infectious disease COVID-19, caused by a new strain of coronavirus, SARS-CoV-2, as a pandemic. Like in all other infectious diseases, the host immune system plays a key role in our defense against SARS-CoV-2 infection. However, viruses are able to evade the immune attack and proliferate and, in susceptible individuals, cause severe inflammatory response known as cytokine storm, particularly in the lungs. The advancement in our understanding of the mechanisms underlying the host immune responses promises to facilitate the development of approaches for prevention or treatment of diseases. Components of immune system, such as antibodies, can also be used to develop sensitive and specific diagnostic methods as well as novel therapeutic agents. In this review, we summarize our knowledge about how the host mounts immune responses to infection by SARS-CoV-2. We also describe the diagnostic methods being used for COVID-19 identification and summarize the current status of various therapeutic strategies, including vaccination, being considered for treatment of the disease.
    日期: 2020-06-04
    關聯: Journal of Biomedical Science. 2020 Jun 4;27:Article number 72.
    Link to: http://dx.doi.org/10.1186/s12929-020-00663-w
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1021-7770&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000540406500001
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85085999594
    显示于类别:[司徒惠康] 期刊論文

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