國家衛生研究院 NHRI:Item 3990099045/12772

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Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/12772

Title:	Association between traffic count and cardiovascular mortality: A prospective cohort study in Taiwan
Authors:	Pan, WC;Yeh, SY;Wu, CD;Huang, YT;Chen, YC;Chen, CJ;Yang, HI
Contributors:	National Institute of Environmental Health Sciences
Abstract:	BACKGROUND: Exposure to traffic-related pollution is positively associated with cardiovascular diseases (CVD), but little was known about how different sources of traffic pollution (e.g. gasoline-powered cars, diesel-engine vehicles) contribute to CVD. Therefore, we evaluated the association between exposure to different types of engine exhaust and CVD mortality. METHODS: We recruited 12,098 participants from REVEAL-HBV cohort in Taiwan. The CVD mortality in 2000-2014 was ascertained by the Taiwan Death Certificates. Traffic pollution sources (2005-2013) were based on information provided by the Directorate General of Highway in 2005. Exposure to PM(2.5) was based on a land-use regression model. We applied Cox proportional hazard models to assess the association of traffic vehicle exposure and CVD mortality. A causal mediation analysis was applied to evaluate the mediation effect of PM(2.5) on the relationship between traffic and CVD mortality. RESULTS: A total of 382 CVD mortalities were identified from 2000 to 2014. We found participants exposed to higher volumes of small car and truck exhausts had an increased CVD mortality. The adjusted hazard ratio (HR) was 1.10 for small cars (95% confidence interval [CI], 0.94-1.27; p-value=0.23) and 1.24 for truck (95% CI, 1.03-1.51; p-value=0.03) per one unit increment of the logarithm scale. The findings were still robust with further adjustment for different types of vehicles. A causal mediation analysis revealed PM(2.5) had an over 60% mediation effect on traffic-CVD association. CONCLUSIONS: Exposure to truck exhaust or gasoline-powered cars is positively associated with CVD mortality, and air pollution may play a role in this association.
Date:	2021-05
Relation:	Journal of Epidemiology. 2021 May;31(5):343-349.
Link to:	http://dx.doi.org/10.2188/jea.JE20200082
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0917-5040&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000637546800007
Cited Times(Scopus):	https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85105939080
Appears in Collections:	[Yu-Cheng Chen] Periodical Articles

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