國家衛生研究院 NHRI:Item 3990099045/13120
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12190/12972 (94%)
造訪人次 : 1060550      線上人數 : 545
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/13120


    題名: Core commitments for field trials of gene drive organisms
    作者: Long, KC;Alphey, L;Annas, GJ;Bloss, CS;Campbell, KJ;Champer, J;Chen, CH;Choudhary, A;Church, GM;Collins, JP;Cooper, KL;Delborne, JA;Edwards, OR;Emerson, CI;Esvelt, K;Evans, SW;Friedman, RM;Gantz, VM;Gould, F;Hartley, S;Heitman, E;Hemingway, J;Kanuka, H;Kuzma, J;Lavery, JV;Lee, Y;Lorenzen, M;Lunshof, JE;Marshall, JM;Messer, PW;Montell, C;Oye, KA;Palmer, MJ;Papathanos, PA;Paradkar, PN;Piaggio, AJ;Rasgon, JL;Rašić, G;Rudenko, L;Saah, JR;Scott, MJ;Sutton, JT;Vorsino, AE;Akbari, OS
    貢獻者: National Institute of Infectious Diseases and Vaccinology
    摘要: Gene drive organisms (GDOs), whose genomes have been genetically engineered to spread a desired allele through a population, have the potential to transform the way societies address a wide range of daunting public health and environmental challenges. The development, testing, and release of GDOs, however, are complex and often controversial. A key challenge is to clarify the appropriate roles of developers and others actively engaged in work with GDOs in decision-making processes, and, in particular, how to establish partnerships with relevant authorities and other stakeholders. Several members of the gene drive community previously proposed safeguards for laboratory experiments with GDOs (1) that, in the absence of national or international guidelines, were considered essential for responsible laboratory work to proceed. Now, with GDO development advancing in laboratories (2–5), we envision similar safeguards for the potential next step: ecologically and/or genetically confined field trials to further assess the performance of GDOs. A GDO's propensity to spread necessitates well-developed criteria for field trials to assess its potential impacts (6). We, as a multidisciplinary group of GDO developers, ecologists, conservation biologists, and experts in social science, ethics, and policy, outline commitments below that we deem critical for responsible conduct of a field trial and to ensure that these technologies, if they are introduced, serve the public interest.
    日期: 2020-12-18
    關聯: Science. 2020 Dec 18;370(6523):1417-1419.
    Link to: http://dx.doi.org/10.1126/science.abd1908
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0036-8075&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000600422900001
    顯示於類別:[陳俊宏] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    PUB33335055.pdf188KbAdobe PDF257檢視/開啟


    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋