國家衛生研究院 NHRI:Item 3990099045/13220
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    题名: Boron-rich, cytocompatible block copolymer nanoparticles by polymerization-induced self-assembly
    作者: Huang, LCS;Le, D;Hsiao, IL;Fritsch-Decker, S;Hald, C;Huang, SC;Chen, JK;Hwu, JR;Weiss, C;Hsu, MH;Delaittre, G
    贡献者: Institute of Biomedical Engineering and Nanomedicine
    摘要: Core-shell nanoparticles (NPs) with a boron-rich core were synthesized by RAFT-mediated polymerization-induced self-assembly using a new methacrylic boronate ester monomer. Under specific conditions, sub-100 nm spherical NPs could be obtained at high conversions by either emulsion or dispersion RAFT polymerization using poly(oligo(ethylene glycol) methacrylate) (POEGMA) dithiobenozate-based chain transfer agents. Phenylboronic acid surface-functionalized NPs were obtained using a telechelic POEGMA. Primary data on biocompatibility is provided and suggests suitability as boron delivery agent for boron neutron capture therapy.
    日期: 2021-01
    關聯: Polymer Chemistry. 2021 Jan;12:50-56.
    Link to: http://dx.doi.org/10.1039/d0py00710b
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1759-9954&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000605451500004
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85099063518
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