國家衛生研究院 NHRI:Item 3990099045/13247
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 12145/12927 (94%)
造访人次 : 907549      在线人数 : 953
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻
    主页 ‧ 登入 ‧ 上传 ‧ 说明 ‧ 关于NHRI ‧ 管理 到手机版


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/13247


    题名: Recent seroepidemiological studies support dengue in Taiwan has not reached endemic yet
    作者: Pan, YH;Chien, YW;Ho, TS;Ko, HY;Chang, SF;Yu, CY;Shu, PY;Chao, DY;Ku, CC;King, CC
    贡献者: National Institute of Infectious Diseases and Vaccinology
    摘要: Background: Dengue epidemics in southern Taiwan have been documented for decades and most outbreaks have been triggered by imported cases from Southeast Asia. Since 1998, most local dengue outbreaks have happened in different magnitudes and scales in southern Taiwan, with the two greatest numbers of cases occurring in Kaohsiung City and Tainan City. From 2014 to 2015, there had been two largest outbreaks caused by DENV-1 and DENV-2 in two consecutive years in Kaohsiung City, while Tainan City had encountered the most severe outbreak of DENV-2 in 2015. Methods and materials:: To understand the post-outbreak herd immunity against dengue virus (DENV) infection, we investigated the seroprevalence rates of DENV infection from 5253 serum samples of older residents in Kaohsiung and Tainan Cities. Seropositive samples were verified to exclude Japanese encephalitis virus (JEV) cross-reaction and the DENV-reconfirmed samples were used to identify viral serotypes and secondary infection. Results: The overall seroprevalence rates of DENV infection was 19.27%, from 5.88% among < 50-year-old to 52.32% in age groups > 80 years. Both DENV seroprevalence rates in Kaohsiung and Tainan increased with age and were significantly lower below 50 years of age than those 70 to 79 and > 80 age groups. Additionally, DENV-1, DENV-2, and DENV-3 covered wider age groups in Kaohsiung, whereas DENV-2 was dominant in Tainan. Conclusion: Both the overall and age-specific seroprevalence rates in southern Taiwan were much lower than those in many Southeast Asian countries. Besides, the predominant DENV serotype in each of the large-scale past epidemics of dengue in Taiwan is also different from multiple DENV serotypes have been co-circulating in many dengue-endemic countries in Southeast Asia. Therefore, our seroepidemiological results plus the predominant DENV serotype causing major outbreaks verify that dengue in Taiwan has not been endemic yet.
    日期: 2020-12
    關聯: International Journal of Infectious Diseases. 2020 Dec;101(Suppl. 1):329.
    Link to: http://dx.doi.org/10.1016/j.ijid.2020.09.865
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1201-9712&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000612135101075
    显示于类别:[余佳益] 會議論文/會議摘要

    文件中的档案:

    档案 描述 大小格式浏览次数
    ISI000612135101075.pdf174KbAdobe PDF194检视/开启


    在NHRI中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈