國家衛生研究院 NHRI:Item 3990099045/13393
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/13393


    Title: Effect of dialyzer membranes on mortality in uremic patients undergoing long-term hemodialysis: A nationwide population-based study using the Taiwan dialysis registry data system 2005-2012
    Authors: Chang, CY;Wu, MS;Chang, CH;Lin, CC;Lin, HL;Kao, CC;Chen, HH;Li, A;Hsu, CC;Lin, YC
    Contributors: Institute of Population Health Sciences
    Abstract: INTRODUCTION: The characteristics in dialyzer is associated with mortality in patients with end-stage renal disease (ESRD) receiving hemodialysis (HD). This study is to investigate the effects of dialyzer membranes on 3-year mortality in ESRD patients. METHODS: From the long-term nationwide population database database. Prevalent HD patient during 2005-2012 were enrolled. Our main analysis to calculate the effect was cox regression multivariate model. RESULTS: Overall, the mean age of all population (N=73,565) was 61.0 ± 13.6 years, observation period is 2.46 years ± 0.98 within 3 years and 64.6% used polysulfone (PS), polymethyl methacrylate (PMMA) (11.6%), polyethersulfone (11.4%), and cellulose triacetate (CTA) (10.7%), EVAL (Hazard ratio [HR] 2.72, 95% confidence interval [CI] 1.71-4.33) and CTA (HR 1.35, 95% CI 1.12-1.64) were associated with higher mortality than PS, but PMMA was not. CONCLUSION: EVAL and CTA adversely affected mortality and PMMA had no protective role. Further investigations on membrane characters on HD patients are warranted. Taipei Medical University (TMU) (TMU-JIRB (No. N201804051).
    Date: 2022-02
    Relation: Therapeutic Apheresis and Dialysis. 2022 Feb;26(1):55-63.
    Link to: http://dx.doi.org/10.1111/1744-9987.13665
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1744-9979&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000651796000001
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85105920748
    Appears in Collections:[Chih-Cheng Hsu] Periodical Articles

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