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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/13409


    Title: High referral accuracy for oral cancers and oral potentially malignant disorders using telemedicine
    Authors: Haron, N;Rajendran, S;Kallarakkal, TG;Zain, RB;Ramanathan, A;Abraham, MT;Lau, SH;Cheng, LC;Chong, SMY;Mohamed Azahar, FA;Mohamad Zaini, Z;Chan, SW;Goh, YC;Lim, D;Khairi, J;Zainal Abidin, M;Abdul Rahman, ZA;Liew, CS;Fong, SC;Yang, YH;Ismail, SM;Cheong, SC
    Contributors: National Institute of Cancer Research
    Abstract: OBJECTIVE: To evaluate the accuracy of MeMoSA(®) , a mobile phone application to review images of oral lesions in identifying oral cancers and oral potentially malignant disorders requiring referral. SUBJECTS AND METHODS: A prospective study of 355 participants, including 280 with oral lesions/variants was conducted. Adults aged ≥18 treated at tertiary referral centres were included. Images of the oral cavity were taken using MeMoSA(®) . The identification of the presence of lesion/variant and referral decision made using MeMoSA(®) were compared to clinical oral examination, using Kappa statistics for intra-rater agreement. Sensitivity, specificity, concordance and F1 score were computed. Images were reviewed by an off-site specialist and inter-rater agreement was evaluated. Images from sequential clinical visits were compared to evaluate observable changes in the lesions. RESULTS: Kappa values comparing MeMoSA(®) with clinical oral examination in detecting a lesion and referral decision was 0.604 and 0.892 respectively. Sensitivity and specificity for referral decision was 94.0% and 95.5%. Concordance and F1 score were 94.9% and 93.3% respectively. Inter-rater agreement for a referral decision was 0.825. Progression or regression of lesions were systematically documented using MeMoSA(®) . CONCLUSION: Referral decisions made through MeMoSA(®) is highly comparable to clinical examination demonstrating it is a reliable telemedicine tool to facilitate the identification of high-risk lesions for early management.
    Date: 2023-03
    Relation: Oral Diseases. 2023 Mar;29(2):380-389.
    Link to: http://dx.doi.org/10.1111/odi.13892
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1354-523X&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000648978300001
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85105527142
    Appears in Collections:[楊奕馨] 期刊論文

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