國家衛生研究院 NHRI:Item 3990099045/14066
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    题名: Association between fine particulate air pollution and the risk of death from lung cancer in Taiwan
    作者: Tsai, SS;Chiu, YW;Weng, YH;Yang, CY
    贡献者: National Institute of Environmental Health Sciences
    摘要: Airborne fine particulate matter (PM(2.5)) has been classified as a Group I carcinogen leading to lung cancer in humans by the International Agency for Research on Cancer (IARC). In Taiwan, where there is a growing incidence of this disease, lung cancer is currently the leading cause of cancer-associated deaths in women and second leading cause of deaths in men. Because tobacco use is rare in Taiwan, especially amongst women, the high incidence of this type of cancer was suggested to be attributed to the other external contaminants, including airborne PM(2) pollution. In this ecologic study, a possible association between ambient air PM(2.5) exposure and likelihood of death attributed to lung cancer was examined in Taiwan in 66 municipalities. Annual PM(2.5) levels and age-standardized lung cancer mortality rates for male and female residents were calculated for years 2010 to 2019. Weighted-multiple regression was applied to analyze our data, adjusting for level of urbanization and physician density. For males, the adjusted risk ratios (RRs) for lung cancer mortality were 1.01 for municipalities with PM(2.5) levels 21.85-28.21 ug/m3 and 1.07 for municipalities with 28.22-31.23 ug/m3, compared to those with the lowest PM(2.5) levels. For females, these adjusted RRs were 0.99 and 1.06, respectively. Data demonstrated an association between chronic exposure to high levels of PM(2.5) and increased likelihood of death attributed to lung cancer for both men and women in Taiwan. Further studies are needed to explore the relationship between PM(2.5) air pollution exposure and risk of lung cancer histologic subtype.
    日期: 2022-05-19
    關聯: Journal of Toxicology and Environmental Health. Part A. 2022 May 09;85(10):431-438.
    Link to: http://dx.doi.org/10.1080/15287394.2022.2040672
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1528-7394&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000761111100001
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85125889086
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