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生技與藥物研究所
張竣評
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Discovery of a long half-life AURKA...
Pulmonary delivery of remdesivir an...
Modulating the affinity and signali...
Synergistic inhibition of SARS-CoV-...
Discovery and synthesis of a pyrimi...
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2024-06-01
Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus
Molecular Cancer Therapeutics. 2024 Jun 01;23(6):766-779.
2023-12
Pulmonary delivery of remdesivir and dexamethasone encapsulated nanostructured lipid carriers for enhanced inflammatory suppression in lung
Journal of Drug Delivery Science and Technology. 2023 Dec;90:Article number 105144.
2023-01
Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists
Bioorganic Chemistry. 2023 Jan;130:Article number 106236.
2021-06-11
Synergistic inhibition of SARS-CoV-2 replication using disulfiram/ebselen and remdesivir[Erratum:ACS Pharmacology and Translational Science. 2021 Apr 9;4(2):898-907.]
ACS Pharmacology and Translational Science. 2021 Jun 11;4(3):Article number 1246.
2021-05-19
Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins
Journal of Medicinal Chemistry. 2021 May 19;64(11):7312-7330.
2021-04-09
Synergistic inhibition of SARS-CoV-2 replication using disulfiram/ebselen and remdesivir
ACS Pharmacology and Translational Science. 2021 Apr 9;4(2):898-907.
2020-12-14
Inhibition of SARS-CoV-2 by highly potent broad-spectrum anti-coronaviral tylophorine-based derivatives
Frontiers in Pharmacology. 2020 Dec 14;11:Article number 606097.
2020-10-08
Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery
Scientific Reports. 2020 Oct 8;10:Article number 16771.
2019-01-01
Fluorine-18 isotope labeling for positron emission tomography imaging. Direct evidence for DBPR211 as a peripherally restricted CB1 inverse agonist
Bioorganic and Medicinal Chemistry. 2019 Jan 1;27(1):216-223.
2018-05-10
Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition
European Journal of Medicinal Chemistry. 2018 May 10;151:533-545.
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