國家衛生研究院 NHRI:Item 3990099045/14256
English  |  正體中文  |  简体中文  |  Items with full text/Total items : 12340/13512 (91%)
Visitors : 2256994      Online Users : 299
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
    •  Adv. Search
    Home ‧ Login ‧ Upload ‧ Help ‧ About ‧ Administer Goto mobile version


    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/14256


    Title: WNK1 kinase signaling in metastasis and angiogenesis
    Authors: Hou, CY;Ma, CY;Yuh, CH
    Contributors: Institute of Molecular and Genomic Medicine
    Abstract: With-no-lysine kinases (WNKs) are a novel family of serine/threonine protein kinases participating in ion homeostasis via the WNK-OSR1/SPAK-NKCC cascade. Recent studies of WNK1 have revealed that its related signaling pathways mediated tumor-induced angiogenesis and carcinogenesis and uncovered novel roles of WNK1 in endothelial cell migration and proliferation, tumor cell proliferation, and metastasis. Herein, we review the functions of WNK1 in cancer metastasis and angiogenesis and propose WNK1 targeting as an anti-cancer strategy.
    Date: 2022-08
    Relation: Cellular Signalling. 2022 Aug;96:Article number 110371.
    Link to: http://dx.doi.org/10.1016/j.cellsig.2022.110371
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0898-6568&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000808581500006
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85131554790
    Appears in Collections:[Chiou-Hwa Yuh] Periodical Articles

    Files in This Item:

    File Description SizeFormat
    PUB35649473.pdf8939KbAdobe PDF295View/Open


    All items in NHRI are protected by copyright, with all rights reserved.

    Related Items in TAIR

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback