國家衛生研究院 NHRI:Item 3990099045/14308
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    题名: Robust synthesis of tetra-boronate esters analogues and the corresponding boronic acids derivatives
    作者: Qiu, SB;Xiao, JH;Chen, PR;Ai, GL;Pan, KL;Chen, JK;Chen, YW;Pan, PS
    贡献者: Institute of Biomedical Engineering and Nanomedicine
    摘要: Organoboron compounds are widely used in catalytic reactions, medicinal chemistry, chemosensors, and polymer applications, because of their low toxicity, high stability, Lewis acidity, chemical versatility, and ability to form covalent bonds with their nucleophilic targets, In this report, we demonstrate how to efficiently assemble tetra boronate-containing compounds at the gram-scale via a one-pot modified microwave-assisted Ugi-4CR reaction. These boronate esters can then be transformed into the corresponding boronic acids under a reliable deprotection method, also reported herein.
    日期: 2022-08-19
    關聯: European Journal of Organic Chemistry. 2022 Aug 19;2022(31):Article number e202200379.
    Link to: http://dx.doi.org/10.1002/ejoc.202200379
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1434-193X&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000803498300001
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85130996365
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