國家衛生研究院 NHRI:Item 3990099045/14597

NHRI > National Institute of Infectious Diseases and Vaccinology > Shu-Chen Kuo > Periodical Articles > Item 3990099045/14597

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/14597

Title:	Contribution of testing strategies and contact tracing towards COVID-19 outbreaks control: A mathematical modeling study
Authors:	Kuo, SC;Fan, B;Zhu, H;Wu, MH;Lee, FJ;Cheng, YC;Wu, HY;Hsu, YT;Hsiung, CA;Wu, SI;Chen, WJ;Chiou, HY;Sytwu, HK;Tsou, HH
Contributors:	National Institute of Infectious Diseases and Vaccinology;Institute of Population Health Sciences;Center for Neuropsychiatric Research
Abstract:	This modeling study considers different screening strategies, contact tracing, and the severity of novel epidemic outbreaks for various population sizes, providing insight into multinational containment effectiveness of emerging infectious diseases, prior to vaccines development. During the period of the ancestral SARS-Cov-2 virus, contact tracing alone is insufficient to achieve outbreak control. Although universal testing is proposed in multiple nations, its effectiveness accompanied by other measures is rarely examined. Our research investigates the necessity of universal testing when contact tracing and symptomatic screening measures are implemented. We used a stochastic transmission model to simulate COVID-19 transmission, evaluating containment strategies via contact tracing, one-time high risk symptomatic testing, and universal testing. Despite universal testing having the potential to identify subclinical cases, which is crucial for non-pharmaceutical interventions, our model suggests that universal testing only reduces the total number of cases by 0.0009% for countries with low COVID-19 prevalence and 0.025% for countries with high COVID-19 prevalence when rigorous contact tracing and symptomatic screening are also implemented. These findings highlight the effectiveness of testing strategies and contact tracing in reducing COVID-19 cases by identifying subclinical cases.
Date:	2022-11
Relation:	Tropical Medicine and Infectious Disease. 2022 Nov;7(11):Article number 376.
Link to:	http://dx.doi.org/10.3390/tropicalmed7110376
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=2414-6366&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000895559300001
Cited Times(Scopus):	https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85149541529
Appears in Collections:	[Shu-Chen Kuo] Periodical Articles [Chao A. Hsiung] Periodical Articles [Shiow-Ing Wu] Periodical Articles [Wei-J. Chen] Periodical Articles [Hung-Yi Chiou] Periodical Articles [Huey-Kang Sytwu] Periodical Articles [Hsiao-Hui Sophie Tsou] Periodical Articles

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