國家衛生研究院 NHRI:Item 3990099045/14608
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    題名: Coarse particulate air pollution and daily mortality: A global study in 205 cities
    作者: Liu, C;Cai, J;Chen, R;Sera, F;Guo, Y;Tong, S;Li, S;Lavigne, E;Correa, PM;Ortega, NV;Orru, H;Maasikmets, M;Jaakkola, JJK;Ryti, N;Breitner, S;Schneider, A;Katsouyanni, K;Samoli, E;Hashizume, M;Honda, Y;Ng, CFS;Diaz, MH;la Cruz Valencia, C;Rao, S;Palomares, ADL;Pereira da Silva, S;Madureira, J;Holobâc, IH;Fratianni, S;Scovronick, N;Garland, RM;Tobias, A;Íñiguez, C;Forsberg, B;Åström, C;Vicedo-Cabrera, AM;Ragettli, MS;Guo, YLL;Pan, SC;Milojevic, A;Bell, ML;Zanobetti, A;Schwartz, J;Gasparrini, A;Kan, H
    貢獻者: National Institute of Environmental Health Sciences
    摘要: Rationale: The associations between ambient coarse particulate matter (PM2.5-10) and daily mortality are not fully understood on a global scale. Objectives: To evaluate the short-term associations between PM2.5-10 and total, cardiovascular, and respiratory mortality across multiple countries/regions worldwide. Methods: We collected daily mortality (total, cardiovascular, and respiratory) and air pollution data from 205 cities in 20 countries/regions. Concentrations of PM2.5-10 were computed as the difference between inhalable and fine PM. A two-stage time-series analytic approach was applied, with overdispersed generalized linear models and multilevel meta-analysis. We fitted two-pollutant models to test the independent effect of PM2.5-10 from copollutants (fine PM, nitrogen dioxide, sulfur dioxide, ozone, and carbon monoxide). Exposure-response relationship curves were pooled, and regional analyses were conducted. Measurements and Main Results: A 10 μg/m3 increase in PM2.5-10 concentration on lag 0-1 day was associated with increments of 0.51% (95% confidence interval [CI], 0.18%-0.84%), 0.43% (95% CI, 0.15%-0.71%), and 0.41% (95% CI, 0.06%-0.77%) in total, cardiovascular, and respiratory mortality, respectively. The associations varied by country and region. These associations were robust to adjustment by all copollutants in two-pollutant models, especially for PM2.5. The exposure-response curves for total, cardiovascular, and respiratory mortality were positive, with steeper slopes at lower exposure ranges and without discernible thresholds. Conclusions: This study provides novel global evidence on the robust and independent associations between short-term exposure to ambient PM2.5-10 and total, cardiovascular, and respiratory mortality, suggesting the need to establish a unique guideline or regulatory limit for daily concentrations of PM2.5-10.
    日期: 2022-09-01
    關聯: American Journal of Respiratory and Critical Care Medicine. 2022 Sep 1;206(8):999-1007.
    Link to: http://dx.doi.org/10.1164/rccm.202111-2657OC
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1535-4970&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000871243100012
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85140144957
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