國家衛生研究院 NHRI:Item 3990099045/1460

NHRI > Institute of Biomedical Engineering and Nanomedicine > Hsu Chang(2004-2017) > Periodical Articles > Item 3990099045/1460

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Title:	Feasibility of transrib focused ultrasound thermal ablation for liver tumors using a spherically curved 2D array: A numerical study
Authors:	Liu, HL;Chang, H;Chen, WS;Shih, TC;Hsiao, JK;Lin, WL
Contributors:	Division of Medical Engineering Research
Abstract:	The use of focused ultrasound thermal ablation to treat hepatocarcinorna and other liver tumors produces promising clinical results. However, one of the major drawbacks is the high absorption of ultrasonic energy by the rib, making partial rib removal necessary in many cases. This study numerically investigated the feasibility of using a spherical ultrasound phased array for transrib liver-tumor thermal ablation. An independently array-element activitation scheme, which switches off the transducer elements obstructed by the ribs based on feedback anatomical medical imaging, was proposed to reduce the rib-overheating problem. The numerical results showed that the proposed treatment planning strategy can effectively reduce the specific energy absorbed by the rib while maintaining the energy at the target position, which both reduces the rib-overheating problem and increases the possibility of treating a target lesion under an intact rib. The analysis also demonstrated that the target position and the ultrasound frequency play key roles in the treatment. Patients with diverse characteristics were also tested to show the generality of the proposed strategy. The proposed treatment planning strategy also provides useful information for evaluating the treatment effectiveness prior to clinically performing transrib ultrasound liver-tumor thermal ablation. (c) 2007 American Association of Physicists in Medicine.
Keywords:	Radiology, Nuclear Medicine & Medical Imaging
Date:	2007-09
Relation:	Medical Physics. 2007 Sep;34(9):3436-3448.
Link to:	http://dx.doi.org/10.1118/1.2759888
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0094-2405&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000249547200004
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=34548299721
Appears in Collections:	[Hsu Chang(2004-2017)] Periodical Articles

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