國家衛生研究院 NHRI:Item 3990099045/14648
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12189/12972 (94%)
造訪人次 : 955661      線上人數 : 773
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/14648


    題名: Role of neuroinflammation in the pathophysiology of traumatic brain injury
    作者: Wu, CYC;Lee, RHC;Lee, MHH;do Couto e Silva, A;Hsieh, TH;Possoit, H;Brackett, AL;Lin, HW
    貢獻者: Institute of Cellular and Systems Medicine
    摘要: Traumatic brain injury (TBI) is a serious public health problem causing morbidity and mortality worldwide yearly. Neuroinflammation is a hallmark symptom following TBI to induce delayed secondary injury. The excessive activation of microglia, astrocytes, and other immunological mediators release pro-inflammatory cytokines causing neuronal cell death leading to neurological deficits. Currently there are no FDA-approved medications to improve cognitive function after TBI, however, the use of fatty acids has gained notoriety in recent years with the use of ω-3 polyunsaturated fatty acids (ω-3 PUFAs, i.e., DHA) providing neuroprotection against TBI-induced neuroinflammation. DHA has been extensively studied in the context of anti-inflammation, but there is a poor understanding of cerebral autoregulation in the presence of TBI. In addition, the current treatments and other potential neuroprotective compounds for TBI such as resveratrol and palmitic acid methyl ester (PAME) are discussed.
    日期: 2018-08-17
    關聯: Neuroinflammation. 2018 Aug 17:563-578.
    Link to: http://dx.doi.org/10.1016/B978-0-12-811709-5.00034-X
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85141294896
    顯示於類別:[其他] 圖書

    文件中的檔案:

    檔案 大小格式瀏覽次數
    SCP85141294896.pdf709KbAdobe PDF138檢視/開啟


    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋