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http://ir.nhri.org.tw/handle/3990099045/14987
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| Title: | Dietary inflammatory patterns are associated with serum TGs and insulin in adults: A community-based study in Taiwan |
| Authors: | Chuang, SC;Wu, IC;Hsiung, CA;Chan, HT;Cheng, CW;Chen, HL;Chiu, YF;Lee, MM;Chang, HY;Hsu, CC |
| Contributors: | Institute of Population Health Sciences;National Center for Geriatrics and Welfare Research |
| Abstract: | BACKGROUND: Dietary patterns related to inflammation have become a focus of disease prevention but the patterns may vary among populations. OBJECTIVE: The study was conducted to determine Taiwanese dietary inflammatory patterns and evaluate their associations with biomarkers of lipid and glucose METHODS: Data were taken from 5,664 community-dwelling individuals aged ≥55 years old recruited in 2009 - 2013 in the Healthy Aging Longitudinal Study in Taiwan (HALST). Dietary data were obtained from a food frequency questionnaire. An empirical dietary inflammatory pattern (EDIP) was derived from reduced rank regression models that explained the serum hsCRP, plasma IL-6, and TNFR1. Cross-sectional associations between dietary scores and biomarkers of total cholesterol (TC); high-density lipoprotein cholesterol (HDLC); low-density lipoprotein cholesterol, triglyceride (TG); and ratios of TG/HDLC, TG/TC, fasting glucose, insulin, and HbA1c were analyzed via multiple linear regression and adjusted for major confounders. The false discovery rate (FDR)-adjusted p <0.05 was considered statistically significant. Abdominal obesity was defined as a waist circumference of ≥90 cm for men and ≥80 cm for women. RESULTS: Higher EDIP-HALST scores were associated with higher TG (per score increment: 1.62%, 95% CI: 0.58-2.76%; p(FDR)=0.01), TG/HDLC (2.01%, 0.67-3.37%; p(FDR)=0.01), and TG/TC (1.42%, 0.41-2.43%; p(FDR)=0.01) and nonlinearly associated with insulin, with those in the middle tertile had the highest serum insulin concentrations (means: 5.12 μIU/mL, 4.78-5.78; p(FDR) =0.04) in men, but not in women. No heterogeneity was detected between sexes. The associations with TG (1.23%, 0.19-2.23%; p(trend)=0.02), TG/HDLC (1.62%, 0.30-2.96%; p(trend)=0.02), and TG/TC (1.11%, 0.11-2.13%; p(trend)=0.03) were stronger in participants with abdominal obesity, but were borderline associated in participants with normal abdominal circumferences (all p(trend)=0.05). CONCLUSIONS: Inflammatory diets, as measured via EDIP-HALST, were associated with serum TG concentration, particularly in participants with abdominal obesity. These findings may suggest that developing disease prevention strategies using dietary inflammatory patterns may be different by populations. |
| Date: | 2023-06 |
| Relation: | Journal of Nutrition. 2023 Jun;153(6):1783-1792. |
| Link to: | http://dx.doi.org/10.1016/j.tjnut.2023.04.015 |
| JIF/Ranking 2023: | http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0022-3166&DestApp=IC2JCR |
| Cited Times(WOS): | https://www.webofscience.com/wos/woscc/full-record/WOS:001013557100001 |
| Cited Times(Scopus): | https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85158110626 |
| Appears in Collections: | [許志成] 期刊論文
[張新儀] 期刊論文
[邱燕楓] 期刊論文
[熊昭] 期刊論文
[吳易謙] 期刊論文
[莊淑鈞] 期刊論文
[其他] 期刊論文
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