國家衛生研究院 NHRI:Item 3990099045/15025

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Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/15025

Title:	Epidemiology and clinical impact of osteoporosis in Taiwan: A 12-year trend of a nationwide population-based study
Authors:	Lee, MT;Fu, SH;Hsu, CC;Chen, HM;Lin, JW;Tsai, KS;Hwang, JS;Lin, SC;Wu, CH;Wang, CY
Contributors:	National Center for Geriatrics and Welfare Research
Abstract:	Background: Osteoporosis increases the fracture and mortality risk of patients and has a higher disease burden than some cancers. Therefore, global concerns regarding the prevention and treatment of osteoporosis have been raised. However, fast-aging Taiwan lacks national epidemiological data on osteoporosis in recent years. We aimed to establish and update epidemiological data on osteoporosis by analyzing national data from 2008 to 2019. Methods: We estimated the prevalence and incidence of osteoporosis in patients aged ≥50 years based on claims data from Taiwan's National Health Insurance database from 2008 to 2019. We also analyzed the key parameters of fracture care (anti-osteoporosis medication use, bone mineral density examination rate, and length of hospital stay) to understand the secular trend of management and related clinical outcomes (imminent refracture rate and mortality). Results: The number of prevalent osteoporosis increased from 2008 to 2015 and remained constant until 2019; however, the age-standardized prevalence and incidence rates declined from 2008 to 2019 (3.77%–2.91% and 2.08%–1.02%, respectively). The overall incidence rates of hip and spine fractures decreased significantly by 34% and 27%, respectively. For patients with hip and spine fractures, the immanent refracture rates were 8.5% and 12.9% and the 1-year mortality rate remained stable at approximately 15% and 6%, respectively. Conclusion: The age-standardized prevalence and incidence rates decreased remarkably from 2008 to 2019, while the number of prevalent osteoporosis remained steady. Patients with hip fractures encountered a high 1-year mortality rate, while the risk of imminent refracture was notable for patients with spine fractures.
Date:	2023-05-17
Relation:	Journal of the Formosan Medical Association. 2023 May 17;122 (Suppl 1):S21-S35.
Link to:	http://dx.doi.org/10.1016/j.jfma.2023.05.001
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0929-6646&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:001087071000004
Cited Times(Scopus):	https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85159288832
Appears in Collections:	[Chen-Yu Wang] Periodical Articles [Chih-Cheng Hsu] Periodical Articles

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