國家衛生研究院 NHRI:Item 3990099045/15046
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    题名: Prevalence of comorbidities and their impact on survival among older adults with the five most common cancers in Taiwan: a population study
    作者: Chien, LH;Tseng, TJ;Chen, TY;Chen, CH;Chen, CY;Jiang, HF;Tsai, FY;Ku, HY;Jiang, SS;Hsiung, CA;Liu, TW;Chang, IS
    贡献者: Institute of Population Health Sciences;National Institute of Cancer Research;Center for Biomedical Resource
    摘要: Because of the cancer incidence increase and population aging in Taiwan, we aimed to assess the cancer prevalence, to summarize the comorbidities of older patients with the five most common cancers (i.e., breast, colorectal, liver, lung, and oral), and to develop a Taiwan cancer comorbidity index (TCCI) for studying their actual prognosis. The linkage of the Taiwan Cancer Registry, Cause of Death Database, and National Health Insurance Research Database was used. We followed the standard statistical learning steps to obtain a survival model with good discriminatory accuracy in predicting death due to noncancer causes, from which we obtained the TCCI and defined comorbidity levels. We reported the actual prognosis by age, stage, and comorbidity level. In Taiwan, cancer prevalence nearly doubled in 2004–2014, and comorbidities were common among older patients. Stage was the major predictor of patients' actual prognoses. For localized and regional breast, colorectal, and oral cancers, comorbidities correlated with noncancer-related deaths. Compared with the US, the chances of dying from comorbidities in Taiwan were lower and the chances of dying from cancer were higher for breast, colorectal, and male lung cancers. These actual prognoses could help clinicians and patients in treatment decision-making and help policymakers in resource planning.
    日期: 2023-04-25
    關聯: Scientific Reports. 2023 Apr 25;13:Article number 6727.
    Link to: http://dx.doi.org/10.1038/s41598-023-29582-0
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=2045-2322&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000984494600040
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85154071317
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