國家衛生研究院 NHRI:Item 3990099045/1517
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    題名: The impact of thermal wave characteristics on thermal dose distribution during thermal therapy: A numerical study
    作者: Shih, TC;Kou, HS;Liauh, CT;Lin, WL
    貢獻者: Division of Medical Engineering Research
    摘要: The aim of this study was to investigate the effects of the propagation speed of a thermal wave in terms of the thermal relaxation time on the temperature/thermal dose distributions in living tissue during thermal therapies. The temperature field in tissue was solved by the finite difference method, and the thermal dose was calculated from the formulation proposed by Sapareto and Dewey [Int. J. Radiat. Oncol. Biol. Phys. 10, 787-800 (1984)]. Under the same total deposited energy, for a rapid heating process the time lagging behavior of the peak temperature became pronounced and the level of the peak temperature was decreased with increasing the thermal relaxation time. When the heating duration was longer than the thermal relaxation time of tissues, there was no significant difference between the thermal dose distributions with/without considering the effect of the thermal relaxation time. In other words, when the heating duration is comparable to or shorter than the thermal relaxation time of tissue, the results of the wave bioheat transfer equation (WBHTE) are fully different from that of the Pennes' bioheat transfer equation (PBHTE). Besides, for a rapid heating process the dimension of thermal lesion was still significantly affected by perfusion, because this is what is predicted by the WBHTE but not by the PBHTE, i.e., the wave feature of the temperature field cannot fully be predicted by the PBHTE. (C) 2005 American Association of Physicists in Medicine.
    關鍵詞: Radiology, Nuclear Medicine & Medical Imaging
    日期: 2005-09
    關聯: Medical Physics. 2005 Sep;32(9):3029-3036.
    Link to: http://dx.doi.org/10.1118/1.2008507
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0094-2405&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000232076700032
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=25644456914
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