國家衛生研究院 NHRI:Item 3990099045/15228
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/15228


    Title: A national case-crossover study on the risk of kidney injury requiring dialysis after sepsis
    Authors: Wong, CS;Chen, TT;Akhmetzhanov, AR;Hu, PJ;Wu, MS;Wu, MY
    Contributors: Center for Neuropsychiatric Research
    Abstract: Background: Patients with sepsis-associated acute kidney injury (AKI) are at risk of kidney damage, potentially necessitating acute temporary or chronic dialysis. Our study aims to estimate the odds ratio (OR) of preceding sepsis among patients requiring their first dialysis. Methods: A nationwide population-based case-only study was conducted using claims records from the National Health insurance database of Taiwan. All patients over 20 years of age who underwent their first dialysis between 2004 and 2016 were included in the study. The six months prior to their first dialysis served as a self-control period. Results: The study included 147,201 patients who required acute temporary and 75,031 patients who required chronic dialysis. The odds ratios for patients needing acute temporary dialysis after 1, 2, 3, and 4 weeks of exposure periods were 15.8, 10.7, 9.2, and 8.4, respectively. The ORs for patients requiring chronic dialysis were 7.0, 4.1, 4.2, and 3.7, respectively. Conclusions: Our findings indicate that sepsis was substantially associated with an increased risk of renal failure. The risk was highest during the first week following sepsis for both acute temporary and chronic dialysis cases.
    Date: 2023-07-27
    Relation: Journal of Clinical Medicine. 2023 Jul 27;12(15):Article number 4950.
    Link to: http://dx.doi.org/10.3390/jcm12154950
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=2077-0383&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:001045573500001
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85168272161
    Appears in Collections:[Others] Periodical Articles

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