國家衛生研究院 NHRI:Item 3990099045/15709
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/15709


    Title: Age at lung cancer diagnosis in females versus males who never smoke by race and ethnicity
    Authors: Blechter, B;Wong, JYY;Chien, LH;Shiraishi, K;Shu, XO;Cai, Q;Zheng, W;Ji, BT;Hu, W;Rahman, ML;Jiang, HF;Tsai, FY;Huang, WY;Gao, YT;Han, X;Steinwandel, MD;Yang, G;Daida, YG;Liang, SY;Gomez, SL;DeRouen, MC;Diver, WR;Reddy, AG;Patel, AV;Le Marchand, L;Haiman, C;Kohno, T;Cheng, I;Chang, IS;Hsiung, CA;Rothman, N;Lan, Q
    Contributors: Institute of Population Health Sciences;National Institute of Cancer Research
    Abstract: Background: We characterized age at diagnosis and estimated sex differences for lung cancer and its histological subtypes among individuals who never smoke. Methods: We analyzed the distribution of age at lung cancer diagnosis in 33,793 individuals across 8 cohort studies and two national registries from East Asia, the United States (US) and the United Kingdom (UK). Student’s t-tests were used to assess the study population differences (Δ years) in age at diagnosis comparing females and males who never smoke across subgroups defined by race/ethnicity, geographic location, and histological subtypes. Results: We found that among Chinese individuals diagnosed with lung cancer who never smoke, females were diagnosed with lung cancer younger than males in the Taiwan Cancer Registry (n = 29,832) (Δ years = −2.2 (95% confidence interval (CI):−2.5, −1.9), in Shanghai (n = 1049) (Δ years = −1.6 (95% CI:-2.9, −0.3), and in Sutter Health and Kaiser Permanente Hawaiʽi in the US (n = 82) (Δ years = −11.3 (95% CI: −17.7, −4.9). While there was a suggestion of similar patterns in African American and non-Hispanic White individuals. the estimated differences were not consistent across studies and were not statistically significant. Conclusions: We found evidence of sex differences for age at lung cancer diagnosis among individuals who never smoke.
    Date: 2024-05
    Relation: British Journal of Cancer. 2024 May;130(8):1286-1294.
    Link to: http://dx.doi.org/10.1038/s41416-024-02592-z
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0007-0920&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:001169647200002
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85185462969
    Appears in Collections:[Chao A. Hsiung] Periodical Articles
    [I-Shou Chang] Periodical Articles

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